Patents by Inventor Seiya FUJIWARA

Seiya FUJIWARA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210222154
    Abstract: The present invention relates to a method for operating magnetic particles in a device in which gel-like medium layer and liquid layer are alternately arranged inside the hollow tube and, first liquid layer and second liquid layer are separated by gel-like medium layer, and magnetic solid with large particle size exists in the first liquid layer rather than magnetic particles and the said magnetic particles. The method of the present invention comprises the first step of moving the magnetic particles and the magnetic solid in the first liquid layer to the gel-like medium layer, the second step of moving the magnetic particles and the magnetic solid moved into the gel-like medium layer into the second liquid layer, and the third step of inverting the movement of the magnetic particles and the magnetic solid moved into the second liquid layer into the gel-like medium layer, by operating a magnetic field.
    Type: Application
    Filed: January 21, 2021
    Publication date: July 22, 2021
    Applicant: SHIMADZU CORPORATION
    Inventors: Akira MURAMATSU, Masamitsu SHIKATA, Masaki KANAI, Seiya FUJIWARA, Tetsuo OHASHI
  • Publication number: 20210129158
    Abstract: In a magnetic particle operation device 1, a plurality of liquid layers 11 and a plurality of gel-like medium layers are alternately arranged. Magnetic particles 13 are introduced into the uppermost liquid layer 11 of the magnetic particle operation device 1, and a holding magnet 60 is in contact with the outer surface of the bulging portion 21 of the container 20. Therefore, during the storage of the device 1, the magnetic particles 13 in the bulging portion 21 are aggregated and held at a position facing the holding magnet 60 in the sample introduction space by the magnetic force of the holding magnet 60. As a result, during the storage of the device 1, the magnetic particles 13 can be prevented from being brought into contact with the gel-like medium layer 12. Further, when the device 1 is used, the magnetic particles 13 can be dispersed in the liquid layer 11 by moving the holding magnet 60 away from the container 20.
    Type: Application
    Filed: April 6, 2017
    Publication date: May 6, 2021
    Inventors: Masaki KANAI, Hiroyuki JIKUYA, Tetsuo OHASHI, Seiya FUJIWARA
  • Publication number: 20200282407
    Abstract: An operation pipe and a device equipped with the operation pipe, which use a gel to perform operations such as separation, extraction, purification, elution, recovery, analysis and the like of target components that are biological components such as nucleic acids. More specifically, an operation pipe and a device, with which it is possible to perform operations such as separation, extraction, purification, elution, recovery, analysis and the like of target components in a sealable pipe by operating magnetic particles in the pipe under a magnetic field from outside of the pipe.
    Type: Application
    Filed: February 5, 2020
    Publication date: September 10, 2020
    Applicant: SHIMADZU CORPORATION
    Inventors: Masamitsu SHIKATA, Ayaka MINAMIMOTO, Akira MURAMATSU, Masaki KANAI, Seiya FUJIWARA, Tetsuo OHASHI, Hiroyuki JIKUYA
  • Patent number: 10684279
    Abstract: To provide a device for operating magnetic particles capable of treating large quantity, and retaining a gel-like medium layer stably, a vessel is formed so that an area perpendicular to a longitudinal direction in a large-diameter part packed with a liquid layer is larger than an area perpendicular to the longitudinal direction in the small-diameter part packed with a gel-like medium layer. Therefore, in the vessel, it is possible to reduce the diameter of the small-diameter part while keeping the capacity of the large-diameter part large. As a result, in the vessel, it is possible to treat large quantity in the liquid layer, and it is possible to retain the gel-like medium layer stably.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: June 16, 2020
    Assignee: SHIMADZU CORPORATION
    Inventors: Masaki Kanai, Hiroyuki Jikuya, Tetsuo Ohashi, Seiya Fujiwara
  • Publication number: 20180224442
    Abstract: To provide a device for operating magnetic particles capable of treating large quantity, and retaining a gel-like medium layer stably, a vessel is formed so that an area perpendicular to a longitudinal direction in a large-diameter part packed with a liquid layer is larger than an area perpendicular to the longitudinal direction in the small-diameter part packed with a gel-like medium layer. Therefore, in the vessel, it is possible to reduce the diameter of the small-diameter part while keeping the capacity of the large-diameter part large. As a result, in the vessel, it is possible to treat large quantity in the liquid layer, and it is possible to retain the gel-like medium layer stably.
    Type: Application
    Filed: February 8, 2018
    Publication date: August 9, 2018
    Applicant: SHIMADZU CORPORATION
    Inventors: Masaki KANAI, Hiroyuki JIKUYA, Tetsuo OHASHI, Seiya FUJIWARA