Patents by Inventor Seiya Mizuno

Seiya Mizuno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR PRODUCING FUSION PROTEIN, NUCLEIC ACID, CELL, AND ANIMAL
    Publication number: 20210189404
    Abstract: A fusion protein including a Cas9 protein and a modifying peptide that modifies the Cas9 protein, in which the modifying peptide includes: a peptide composed of the amino acid sequence described in SEQ ID NO: 29; or a peptide composed of an amino acid sequence in which one or several amino acids are deleted, substituted, or added in the amino acid sequence described in SEQ ID NO: 29 and having activity to localize the Cas9 protein in the nucleus by forming a fusion protein with the Cas9 protein.
    Type: Application
    Filed: May 22, 2019
    Publication date: June 24, 2021
    Inventors: Seiya MIZUNO, Fumihiro SUGIYAMA, Satoru TAKAHASHI, Saori MIZUNO
  • T-die and method of manufacturing the same
    Patent number: 10493565
    Abstract: On at least the edge portion (9e) of the lip portion (9) of a T-die (1), a cladding layer (10) is provided. The cladding layer is formed by laser build-up welding to a base material with a powder of a corrosion resistant and wear resistant alloy comprising a nickel-based alloy or a cobalt-based alloy. The cladding layer has a metallographic structure in which metal borides are dispersed in a binder phase. The lip portion has high quality and has high durability. The manufacturing costs of the T-die can also be kept relatively low.
    Type: Grant
    Filed: September 13, 2016
    Date of Patent: December 3, 2019
    Assignee: Toshiba Kikai Kabushiki Kaisha
    Inventors: Shuhei Honma, Ryota Oke, Yosuke Ogino, Tomonori Yamaguchi, Seiya Mizuno
  • T-DIE AND METHOD OF MANUFACTURING THE SAME
    Publication number: 20170066085
    Abstract: On at least the edge portion (9e) of the lip portion (9) of a T-die (1), a cladding layer (10) is provided. The cladding layer is formed by laser build-up welding to a base material with a powder of a corrosion resistant and wear resistant alloy comprising a nickel-based alloy or a cobalt-based alloy. The cladding layer has a metallographic structure in which metal borides are dispersed in a binder phase. The lip portion has high quality and has high durability. The manufacturing costs of the T-die can also be kept relatively low.
    Type: Application
    Filed: September 13, 2016
    Publication date: March 9, 2017
    Applicant: Toshiba Kikai Kabushiki Kaisha
    Inventors: Shuhei Honma, Ryota Oke, Yosuke Ogino, Tomonori Yamaguchi, Seiya Mizuno
  • T-DIE AND METHOD OF MANUFACTURING THE SAME
    Publication number: 20150258724
    Abstract: On at least the edge portion (9e) of the lip portion (9) of a T-die (1), a cladding layer (10) is provided. The cladding layer is formed by laser build-up welding to a base material with a powder of a corrosion resistant and wear resistant alloy comprising a nickel-based alloy or a cobalt-based alloy. The cladding layer has a metallographic structure in which metal borides are dispersed in a binder phase. The lip portion has high quality and has high durability. The manufacturing costs of the T-die can also be kept relatively low.
    Type: Application
    Filed: August 30, 2013
    Publication date: September 17, 2015
    Applicant: Toshiba Kikai Kabushiki Kaisha
    Inventors: Shuhei Honma, Ryota Oke, Yosuke Ogino, Tomonori Yamaguchi, Seiya Mizuno