Patents by Inventor Seiya Yamayoshi

Seiya Yamayoshi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RECOMBINANT INFLUENZA VIRUSES WITH STABILIZED NA
    Publication number: 20240010995
    Abstract: Modified influenza virus neuraminidases are described herein that have stabilized NA tetramers which may improve vaccine production efficiency, thus improving the yield of vaccine viruses.
    Type: Application
    Filed: August 3, 2023
    Publication date: January 11, 2024
    Inventors: Yoshihiro Kawaoka, Yuri Furusawa, Seiya Yamayoshi
  • HUMAN ANTIBODY OR ANTIGEN-BINDING FRAGMENT THEREOF AGAINST CORONAVIRUS SPIKE PROTEIN
    Publication number: 20230312689
    Abstract: It is an object of the present invention to provide antibodies against coronavirus (SARS-CoV-2). It is also an object of the present invention to provide a pharmaceutical composition against coronavirus infection using the antibody. According to the present invention, an antibody or antigen-binding fragment thereof that binds to the receptor-binding domain present in the spike protein of coronavirus and is capable of neutralizing the coronavirus, and a pharmaceutical composition for the prevention or treatment of coronavirus infection containing the antibody or antigen-binding fragment, are provided.
    Type: Application
    Filed: July 9, 2021
    Publication date: October 5, 2023
    Applicants: NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY, The University of Tokyo
    Inventors: Shuzo MATSUSHITA, Yu KAKU, Takeo KUWATA, Yoshihiro KAWAOKA, Masaki IMAI, Seiya YAMAYOSHI
  • Recombinant influenza viruses with stabilized NA
    Patent number: 11739303
    Abstract: Modified influenza virus neuraminidases are described herein that have stabilized NA tetramers which may improve vaccine production efficiency, thus improving the yield of vaccine viruses.
    Type: Grant
    Filed: January 22, 2021
    Date of Patent: August 29, 2023
    Assignees: Wisconsin Alumni Research Foundation (WARF), The University of Tokyo
    Inventors: Yoshihiro Kawaoka, Yuri Furusawa, Seiya Yamayoshi
  • NUCLEIC ACID LIPID PARTICLE VACCINE
    Publication number: 20230248819
    Abstract: The present invention provides a vaccine for preventing and/or treating infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The present invention relates to a lipid particle encapsulating a nucleic acid molecule capable of expressing the S protein and/or a fragment thereof of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), wherein the lipid comprises a cationic lipid represented by general formula (Ia) or a pharmaceutically acceptable salt thereof: wherein R1 and R2 each independently represent a C1-C3 alkyl group; L1 represents a C17-C19 alkenyl group which may have one or a plurality of C2-C4 alkanoyloxy groups; L2 represents a C10-C19 alkyl group which may have one or a plurality of C2-C4 alkanoyloxy groups or a C10-C19 alkenyl group which may have one or a plurality of C2-C4 alkanoyloxy groups; and p is 3 or 4.
    Type: Application
    Filed: June 10, 2021
    Publication date: August 10, 2023
    Inventors: Yoshihiro KAWAOKA, Masaki IMAI, Seiya YAMAYOSHI, Ken ISHII, Kouji KOBIYAMA, Eiko NAMBA, Tatsuya OKA, Miyuki TOZUKA, Nao JONAI, Yoshikuni ONODERA, Fumihiko TAKESHITA, Takashi SUZUKI, Takako NIWA, Makoto KOIZUMI, Kensuke NAKAMURA
  • RECOMBINANT INFLUENZA VIRUSES WITH STABILIZED NA
    Publication number: 20210246432
    Abstract: Modified influenza virus neuraminidases are described herein that have stabilized NA tetramers which may improve vaccine production efficiency, thus improving the yield of vaccine viruses.
    Type: Application
    Filed: January 22, 2021
    Publication date: August 12, 2021
    Inventors: Yoshihiro Kawaoka, Yuri Furusawa, Seiya Yamayoshi