Patents by Inventor Selvi Srinivasan

Selvi Srinivasan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CELL BASED METHODS AND COMPOSITIONS FOR THERAPEUTIC AGENT DELIVERY AND TREATMENTS USING SAME
    Publication number: 20200405881
    Abstract: Provided herein are engineered cells and methods for engineering cells to deliver a therapeutic agent, e.g., a small molecule, peptide or other drug, to a cell or tissue to be treated.
    Type: Application
    Filed: March 6, 2018
    Publication date: December 31, 2020
    Applicants: UNIVERSITY OF WASHINGTON, SEATTLE CHILDREN'S RESEARCH INSTITUTE, COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
    Inventors: Patrick S. STAYTON, Anthony CONVERTINE, Debobrato DAS, Hye-Nam SON, Selvi SRINIVASAN, Katherine MONTGOMERY, Ian BLUMENTHAL, Courtney CRANE, Michael JENSEN, James MATTHAEI, John CHIEFARI, Maarten DANIAL, Fei HUANG, James MACDONALD, Almar POSTMA, Kathleen TURNER
  • Stabilized polymeric carriers for therapeutic agent delivery
    Patent number: 10709791
    Abstract: Polymeric carriers for the delivery of therapeutic agents and methods for making and using the same. The polymeric carriers include copolymers, diblock copolymers, polymeric architectures that include the copolymers and diblock copolymers, and particles assemblies comprising the copolymers, diblock copolymers, and polymeric architectures that include the copolymers.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: July 14, 2020
    Assignee: University of Washington
    Inventors: Patrick S. Stayton, Anthony J. Convertine, Daniel M. Ratner, Debobrato Das, Selvi Srinivasan
  • RANDOM COPOLYMER THERAPEUTIC AGENT CARRIERS AND ASSEMBLIES THEREOF
    Publication number: 20190365906
    Abstract: Provided herein are particles assemblies including a shell surrounding a core. The shell includes a particle-stabilizing random copolymer. The core includes a core random copolymer. The particle assemblies have a biomimetic design in which the polymeric components containing discrete chemical and biological functionalities are designed to spontaneously self-assemble into particles. Also provided herein are random copolymers having conjugated therapeutic agents that can be cleaved from the copolymers by an enzyme or water.
    Type: Application
    Filed: April 11, 2019
    Publication date: December 5, 2019
    Applicant: University of Washington through its Center for Commercialization
    Inventors: Patrick S. Stayton, Anthony Convertine, Daniel M. Ratner, Selvi Srinivasan, Debobrato Das, Fang-Yi Su, Jasmin Chen, David Yee-Shawn Chiu, Daniel Douglas Lane
  • STABILIZED POLYMERIC CARRIERS FOR THERAPEUTIC AGENT DELIVERY
    Publication number: 20180043029
    Abstract: Polymeric carriers for the delivery of therapeutic agents and methods for making and using the same. The polymeric carriers include copolymers, diblock copolymers, polymeric architectures that include the copolymers and diblock copolymers, and particles assemblies comprising the copolymers, diblock copolymers, and polymeric architectures that include the copolymers.
    Type: Application
    Filed: November 12, 2015
    Publication date: February 15, 2018
    Applicant: University of Washington
    Inventors: Patrick S. Stayton, Anthony J. Convertine, Daniel M. Ratner, Debobrato Das, Selvi Srinivasan
  • STIMULI-RESPONSIVE POLYMER DIAGNOSTIC ASSAY COMPRISING MAGNETIC NANOPARTICLES AND CAPTURE CONJUGATES
    Publication number: 20170030900
    Abstract: The present disclosure utilizes the aggregation of stimuli-responsive polymers to isolate a diagnostic target (e.g., an antigen) from a solution using magnetophoresis. Isolating the diagnostic target provides a route to identify the presence of the diagnostic target in the solution.
    Type: Application
    Filed: August 4, 2016
    Publication date: February 2, 2017
    Applicant: University of Washington through its Center for Commercialization
    Inventors: Patrick S. Stayton, Jriuan Lai, Barrett J. Nehilla, Selvi Srinivasan
  • RANDOM COPOLYMER THERAPEUTIC AGENT CARRIERS AND ASSEMBLIES THEREOF
    Publication number: 20160279251
    Abstract: Provided herein are particles assemblies including a shell surrounding a core. The shell includes a particle-stabilizing random copolymer. The core includes a core random copolymer. The particle assemblies have a biomimetic design in which the polymeric components containing discrete chemical and biological functionalities are designed to spontaneously self-assemble into particles. Also provided herein are random copolymers having conjugated therapeutic agents that can be cleaved from the copolymers by an enzyme or water.
    Type: Application
    Filed: November 12, 2014
    Publication date: September 29, 2016
    Applicant: University of Washington through its Center for Commercialization
    Inventors: Patrick S. Stayton, Anthony Convertine, Daniel M. Ratner, Selvi Srinivasan, Debobrato Das, Fang-Yi Su, Jasmin Chen, David Yee-Shawn Chiu, Daniel Douglas Lane
  • Stimuli-responsive polymer diagnostic assay comprising magnetic nanoparticles and capture conjugates
    Patent number: 9429570
    Abstract: The present disclosure utilizes the aggregation of stimuli-responsive polymers to isolate a diagnostic target (e.g., an antigen) from a solution using magnetophoresis. Isolating the diagnostic target provides a route to identify the presence of the diagnostic target in the solution.
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: August 30, 2016
    Assignee: University of Washington through its Center for Commercialization
    Inventors: Patrick S. Stayton, Jriuan Lai, Barrett J. Nehilla, Selvi Srinivasan
  • STIMULI-RESPONSIVE POLYMER DIAGNOSTIC ASSAY COMPRISING MAGNETIC NANOPARTICLES AND CAPTURE CONJUGATES
    Publication number: 20150268236
    Abstract: The present disclosure utilizes the aggregation of stimuli-responsive polymers to isolate a diagnostic target (e.g., an antigen) from a solution using magnetophoresis. Isolating the diagnostic target provides a route to identify the presence of the diagnostic target in the solution.
    Type: Application
    Filed: June 5, 2015
    Publication date: September 24, 2015
    Applicant: University of Washington through its Center for Commercialization
    Inventors: Patrick S. Stayton, Jriuan Lai, Barrett J. Nehilla, Selvi Srinivasan
  • Stimuli-responsive polymer diagnostic assay comprising magnetic nanoparticles and capture conjugates
    Patent number: 9080933
    Abstract: The present disclosure utilizes the aggregation of stimuli-responsive polymers to isolate a diagnostic target (e.g., an antigen) from a solution using magnetophoresis. Isolating the diagnostic target provides a route to identify the presence of the diagnostic target in the solution.
    Type: Grant
    Filed: May 9, 2013
    Date of Patent: July 14, 2015
    Assignee: University of Washington through its Center for Commercialization
    Inventors: Patrick S. Stayton, Jriuan Lai, Barrett J. Nehilla, Selvi Srinivasan
  • STIMULI-RESPONSIVE POLYMER DIAGNOSTIC ASSAY COMPRISING MAGNETIC NANOPARTICLES AND CAPTURE CONJUGATES
    Publication number: 20130295585
    Abstract: The present disclosure utilizes the aggregation of stimuli-responsive polymers to isolate a diagnostic target (e.g., an antigen) from a solution using magnetophoresis. Isolating the diagnostic target provides a route to identify the presence of the diagnostic target in the solution.
    Type: Application
    Filed: May 9, 2013
    Publication date: November 7, 2013
    Inventors: Patrick S. Stayton, Jriuan Lai, Barrett J. Nehilla, Selvi Srinivasan