Patents by Inventor Semih Ullah Tareen

Semih Ullah Tareen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein
    Patent number: 8323662
    Abstract: Materials and methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein are provided. More specifically, methods for generating such materials include culturing in a culture medium including kifunensine a virus packaging cell with a lentiviral vector genome including a polynucleotide encoding an exogenous antigen, a polynucleotide encoding a Sindbis E2 glycoprotein that preferentially binds dendritic cells expressing DC-SIGN, and a polynucleotide encoding a Vpx protein or a Vpr protein that retains SAMHD1-inhibiting activity, followed by isolating a pseudotyped lentiviral vector particle that preferentially binds dendritic cells expressing DC-SIGN.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: December 4, 2012
    Assignee: Immune Design Corp.
    Inventors: Christopher James Nicolai, Semih Ullah Tareen