Patents by Inventor Sen Ji

Sen Ji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Plasmin inhibitor, preparation method therefor and application thereof
    Patent number: 12649755
    Abstract: A compound of formula (I) capable of inhibiting plasmin activity, delaying fibrinolysis, and having coagulation and hemostatic activity, pharmaceutically acceptable salts, hydrates, isomers, prodrugs and mixtures thereof, wherein X, and R1 to R5 are as defined in the description.
    Type: Grant
    Filed: December 30, 2021
    Date of Patent: June 9, 2026
    Assignee: SCINNOHUB PHARMACEUTICAL CO., LTD
    Inventors: Anle Yang, Sen Ji, Zhi Wang, Hao Wang, Dewei Zhang, Xiao Wang, Huan Shen, Jie Xiang, Jialing Xian, Yan Wang, Xiao Hu, Xiaodong Zhang, Jun Tang
  • Tetrahydronaphthyridine Derivatives, Medicine Prepared Therefrom, and Applications Thereof in Preventing and Treating Adhesion-related Diseases
    Publication number: 20260151410
    Abstract: A tetrahydronaphthyridine derivative is used in preparing a medicine. The tetrahydronaphthyridine derivative is effective in preventing and treating gastrointestinal tract injury-related diseases or inhibiting gastrointestinal protein kinase.
    Type: Application
    Filed: May 29, 2023
    Publication date: June 4, 2026
    Inventors: Xiao HU, Yan WANG, Sen JI, Xiao WANG, Xiaodong ZHANG, Jun TANG
  • COMPOUND FOR REGULATING AND CONTROLLING ACTIVITY OF 15-PGDH AND PREPARATION METHOD THEREFOR
    Publication number: 20260001892
    Abstract: Provided are a compound of formula (I) having an effect of regulating and controlling the activity of 15-PGDH, a stereoisomer, a tautomer or a form of a mixture thereof, or a pharmaceutically acceptable salt thereof, or a solvate thereof, or a prodrug thereof, a pharmaceutical composition comprising same, and a preparation method therefor and the use thereof as a 15-PGDH inhibitor.
    Type: Application
    Filed: July 21, 2023
    Publication date: January 1, 2026
    Inventors: Sen JI, Hao WANG, Wenqing ZHANG, Xiao WANG, Nan LI, Jing WANG, Yuanqing TANG, Xiaodong ZHANG, Jun TANG
  • USE OF TETRAHYDRONAPHTHYRIDINE DERIVATIVE FOR PREPARING PRODUCT FOR IMPROVING HYPERPIGMENTATION
    Publication number: 20250325526
    Abstract: A compound represented by formula I, a pharmaceutically acceptable salt, a hydrate, an isomer, a prodrug, or a mixture thereof are suitable for preparing a product for improving hyperpigmentation. The compound may be effective in treating melasma.
    Type: Application
    Filed: May 29, 2023
    Publication date: October 23, 2025
    Inventors: Xiao HU, Yan WANG, Sen JI, Xiao WANG, Xiaodong ZHANG, Jun TANG
  • COMPOUND CAPABLE OF REGULATING AND CONTROLLING ACTIVITY OF 15-PGDH, AND PREPARATION METHOD THEREFOR
    Publication number: 20250250283
    Abstract: Disclosed are a compound of formula (I) capable of regulating and controlling the activity of 15-PGDH, or a stereoisomer thereof, a tautomer thereof or a mixture thereof, or a pharmaceutically acceptable salt thereof, or a solvate thereof, or a prodrug thereof, a pharmaceutical composition comprising the same, and use of the compound in the preparation of a 15-PGDH inhibitor.
    Type: Application
    Filed: April 13, 2023
    Publication date: August 7, 2025
    Inventors: Sen JI, Hao WANG, Wenqing ZHANG, Jie LIANG, Xiao WANG, Lin TIAN, Ze FENG, Nan LI, Yuangqing TANG, Jing WANG, Xiaodong ZHANG, Jun TANG
  • COMPOUND FOR REGULATING AND CONTROLLING 15-PGDH ACTIVITY AND PREPARATION METHOD THEREFOR
    Publication number: 20250154162
    Abstract: The present application relates to a compound represented by formula (I) and used for regulating and controlling the 15-PGDH activity and an application thereof in the pharmaceutical field. The present application further provides a method for preparing the compound of the present application, a composition comprising the compound of the present application, and a pharmaceutical use of the compound in serving as a 15-PGDH inhibitor.
    Type: Application
    Filed: January 20, 2023
    Publication date: May 15, 2025
    Inventors: Anle YANG, Sen JI, Hao WANG, Dewei ZHANG, Xiao WANG, Xinying QIAN, Zhiyong LI, Xiaodong ZHANG, Jun TANG
  • PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
    Publication number: 20240300986
    Abstract: A compound of formula (I) capable of inhibiting plasmin activity, delaying fibrinolysis, and having coagulation and hemostatic activity, pharmaceutically acceptable salts, hydrates, isomers, prodrugs and mixtures thereof, wherein X, and R1 to R5 are as defined in the description.
    Type: Application
    Filed: December 30, 2021
    Publication date: September 12, 2024
    Inventors: Anle YANG, Sen JI, Zhi WANG, Hao WANG, Dewei ZHANG, Xiao WANG, Huan SHEN, Jie XIANG, Jialing XIAN, Yan WANG, Xiao HU, Xiaodong ZHANG, Jun TANG
  • PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
    Publication number: 20240124443
    Abstract: The present invention relates to a compound of formula (I) capable of inhibiting plasmin activity and having blood coagulation and hemostasis activity, and a pharmaceutically acceptable salt, hydrate, isomer, prodrug and mixture thereof, wherein R1 to R3 are as defined in the description.
    Type: Application
    Filed: January 28, 2022
    Publication date: April 18, 2024
    Inventors: Anle YANG, Sen JI, Zhi WANG, Hao WANG, Dewei ZHANG, Xiao WANG, Huan SHEN, Jie XIANG, Jialing XIAN, Yan WANG, Xiao HU, Xiaodong ZHANG, Jun TANG
  • Cardiac Lead for Epicardial, Endocardial and Trans-Coronary Sinus Placement
    Publication number: 20120330122
    Abstract: A cardiac lead includes a half-domed, or semi-spherical shaped, or asymmetrical oval or circular distal assembly with or without an active fixation mechanism. The half-domed or semi-spherical or asymmetrical oval or circular shape provides directionality as to whether a flat side of the lead is facing the myocardial tissue and therefore the active fixation mechanism can be deployed safely into the myocardial tissue. Pacing/sensing electrodes may be constructed on the flat side of the lead to avoid the stimulation of the phrenic nerve.
    Type: Application
    Filed: June 22, 2012
    Publication date: December 27, 2012
    Inventors: Sen Ji, Danya Zhang
  • Cardiac Lead for Epicardial, Endocardial and Trans-Coronary Sinus Placement
    Publication number: 20110218604
    Abstract: A cardiac lead includes a half-domed or semi-spherical shaped distal assembly and an active fixation mechanism. The half-domed or semi-spherical shape provides directionality as to whether a flat side of the lead is facing the myocardial tissue and therefore the active fixation mechanism can be deployed safely into the myocardial tissue.
    Type: Application
    Filed: March 1, 2011
    Publication date: September 8, 2011
    Inventors: Sen Ji, Danya Zhang
  • ESOPHAGIAL VISUALIZATION DEVICE
    Publication number: 20100094129
    Abstract: This invention relates to a device for continuously visualizing the esophagus during atrial finrillation ablation procedure to reduce the risk of developing atrio-esophagial fistula as the result of atrial fibrillation ablation.
    Type: Application
    Filed: December 18, 2007
    Publication date: April 15, 2010
    Inventors: Frank Marchilinski, Sen Ji