Abstract: A multi-pinhole collimator is formed by calculating a projection size (D) for different pinhole numbers (n) for a predetermined field-of-view (FOV) (d) by arranging a plurality of projections into a pattern. A pattern is selected which utilizes a whole detector with maximized packing density, minimum truncation to provide a projection overlap below a predetermined limit. The number of pinholes is modified to calculate a collimator length, a corresponding acceptance angle and aperture size. Sensitivities for individual pinholes are added to obtain a total sensitivity for a given pinhole number, and an optimized multi-pinhole configuration is obtained by maximizing the total sensitivity for a predetermined target resolution (Rt) and field-of-view (FOV) (d).

Abstract: A multi-pinhole collimator is formed by calculating a projection size (D) for different pinhole numbers (n) for a predetermined field-of-view (FOV) (d) by arranging a plurality of projections into a pattern. A pattern is selected which utilizes a whole detector with maximized packing density, minimum truncation to provide a projection overlap below a predetermined limit. The number of pinholes is modified to calculate a collimator length, a corresponding acceptance angle and aperture size. Sensitivities for individual pinholes are added to obtain a total sensitivity for a given pinhole number, and an optimized multi-pinhole configuration is obtained by maximizing the total sensitivity for a predetermined target resolution (Re) and field-of-view (FOV) (d).

Abstract: The present invention relates to systems and methods for attenuation correction to improve reconstructed image quality and quantitative accuracy and reduce radiation dose in emission computed tomography. In one embodiment, the present invention provides an interpolated average CT (IACT) method and breathing control devices.