Patents by Inventor Senhao XIAO

Senhao XIAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bromodomain inhibitor compound and use thereof
    Patent number: 11427593
    Abstract: The present invention relates to a bromodomain inhibitor. Provided are a compound represented by general formula I or a pharmaceutically acceptable salt, enantiomer, diastereomer, atropisomer, racemate, polymorph, solvate, or isotopically labeled compound (including deuterium substitution) thereof, a preparation method of the same, a pharmaceutical composition comprising the same, and a pharmaceutical use thereof.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: August 30, 2022
    Assignees: Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Suzhou Suplead Life Sciences Co., Ltd.
    Inventors: Bing Zhou, Cheng Luo, Zizhou Li, Yaxi Yang, Shijie Chen, Hong Ding, Hualiang Jiang, Gang Qiao, Xinjun Wang, Senhao Xiao
  • HISTONE ACETYLTRANSFERASE (HAT) INHIBITOR AND USE THEREOF
    Publication number: 20220002278
    Abstract: Disclosed is a histone acetyltransferase (HAT) inhibitor. Provided are a compound represented by the general formula I, a pharmaceutically acceptable salt, a stereoisomer, an enantiomer, a diastereoisomer, an atropisomer, a racemate, a polymorph, a solvate or an isotope-labeled compound (including deuterium substitution) thereof, a preparation method therefor, a pharmaceutical composition comprising same and use thereof in the treatment of various HAT-related diseases or conditions.
    Type: Application
    Filed: October 20, 2020
    Publication date: January 6, 2022
    Inventors: Bing Zhou, Cheng Luo, Hualiang Jiang, Yaxi Yang, Lianghe Mei, Wenchao Lu, Senhao Xiao, Shijie Chen, Shili Wan, Gang Qiao, Rukang Zhang
  • HISTONE ACETYLTRANSFERASE (HAT) INHIBITOR AND USE THEREOF
    Publication number: 20210101891
    Abstract: Disclosed is a histone acetyltransferase (HAT) inhibitor. Provided are a compound represented by the general formula I, a pharmaceutically acceptable salt, a stereoisomer, an enantiomer, a diastereoisomer, an atropisomer, a racemate, a polymorph, a solvate or an isotope-labeled compound (including deuterium substitution) thereof, a preparation method therefor, a pharmaceutical composition comprising same and use thereof in the treatment of various HAT-related diseases or conditions.
    Type: Application
    Filed: October 20, 2020
    Publication date: April 8, 2021
    Inventors: Bing Zhou, Cheng Luo, Hualiang Jiang, Yaxi Yang, Lianghe Mei, Wenchao Lu, Senhao Xiao, Shijie Chen, Shili Wan, Gang Qiao, Rukang Zhang
  • BROMODOMAIN INHIBITOR COMPOUND AND USE THEREOF
    Publication number: 20200354371
    Abstract: The present invention relates to a bromodomain inhibitor. Provided are a compound represented by general formula I or a pharmaceutically acceptable salt, enantiomer, diastereomer, atropisomer, racemate, polymorph, solvate, or isotopically labeled compound (including deuterium substitution) thereof, a preparation method of the same, a pharmaceutical composition comprising the same, and a pharmaceutical use thereof.
    Type: Application
    Filed: January 11, 2019
    Publication date: November 12, 2020
    Inventors: Bing ZHOU, Cheng LUO, Zizhou LI, Yaxi YANG, Shijie CHEN, Hong DING, Hualiang JIANG, Gang QIAO, Xinjun WANG, Senhao XIAO