Patents by Inventor Senthil Kumar RAMAN

Senthil Kumar RAMAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SELF-ASSEMBLING PROTEIN NANOPARTICLES ENCAPSULATING IMMUNOSTIMULATORY NUCLEID ACIDS
    Publication number: 20240075120
    Abstract: The present invention relates to self-assembling protein nanoparticles encapsulating immunostimulatory nucleid acids. Furthermore, the invention relates to the use of such nanoparticles for vaccination.
    Type: Application
    Filed: April 7, 2023
    Publication date: March 7, 2024
    Inventors: Caroline KULANGARA, Sara Maria PAULILLO, Matteo PIAZZA, Senthil Kumar RAMAN, Peter BURKHARD
  • SELF-ASSEMBLING PROTEIN NANOPARTICLES WITH BUILT-IN SIX-HELIX BUNDLE PROTEINS
    Publication number: 20230340031
    Abstract: The present invention relates to self-assembling protein nanoparticles with built-in six-helix bundle proteins. Proteins or peptides comprising a loop region are stabilized by attaching them to six-helix bundle (SHB) proteins and integrating them into self-assembling protein nanoparticles (SAPNs).
    Type: Application
    Filed: March 24, 2023
    Publication date: October 26, 2023
    Inventors: Caroline KULANGARA, Sara Maria PAULILLO, Matteo PIAZZA, Senthil Kumar RAMAN, Peter BURKHARD
  • SELF-ASSEMBLING PROTEIN NANOPARTICLES ENCAPSULATING IMMUNOSTIMULATORY NUCLEID ACIDS
    Publication number: 20200061172
    Abstract: The present invention relates to self-assembling protein nanoparticles encapsulating immunostimulatory nucleid acids. Furthermore, the invention relates to the use of such nanoparticles for vaccination.
    Type: Application
    Filed: February 22, 2018
    Publication date: February 27, 2020
    Inventors: Caroline KULANGARA, Sara Maria PAULILLO, Matteo PIAZZA, Senthil Kumar RAMAN, Peter BURKHARD
  • SELF-ASSEMBLING PROTEIN NANOPARTICLES WITH BUILT-IN SIX-HELIX BUNDLE PROTEINS
    Publication number: 20200017554
    Abstract: The present invention relates to self-assembling protein nanoparticles with built-in six-helix bundle proteins. Proteins or peptides comprising a loop region are stabilized by attaching them to six-helix bundle (SHB) proteins and integrating them into self-assembling protein nanoparticles (SAPNs).
    Type: Application
    Filed: March 22, 2018
    Publication date: January 16, 2020
    Inventors: Caroline KULANGARA, Sara Maria PAULILLO, Matteo PIAZZA, Senthil Kumar RAMAN, Peter BURKHARD
  • Flagellin-containing protein nanoparticles as a vaccine platform
    Patent number: 10245318
    Abstract: The present invention relates to self-assembling protein nanoparticles constructed from suitable oligomerization domains and further incorporating the TLR5 binding protein flagellin as an adjuvant molecule. Furthermore, the invention relates to the use of such nanoparticles for vaccination.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: April 2, 2019
    Assignee: ALPHA-O PEPTIDES AG
    Inventors: Peter Burkhard, Senthil Kumar Raman, Sara Maria Paulillo, Matteo Piazza, Caroline Kulangara, Christian Mittelholzer
  • FLAGELLIN-CONTAINING PROTEIN NANOPARTICLES AS A VACCINE PLATFORM
    Publication number: 20160324958
    Abstract: The present invention relates to self-assembling protein nanoparticles constructed from suitable oligomerization domains and further incorporating the TLR5 binding protein flagellin as an adjuvant molecule. Furthermore, the invention relates to the use of such nanoparticles for vaccination.
    Type: Application
    Filed: January 9, 2015
    Publication date: November 10, 2016
    Applicant: ALPHA-O PEPTIDES AG
    Inventors: Peter BURKHARD, Senthil Kumar RAMAN, Sara Maria PAULILLO, Matteo PIAZZA, Caroline KULANGARA, Christian MITTELHOLZER