Abstract: Proposed are a portable thermal block module, a temperature variable system for a reaction vessel comprising same, and an on-site analysis device comprising same. The portable thermal block module may include a heating element, a thermal block stacked on the heating element, and a fixed unit. The thermal block may include a substrate and one or more bodies. The one or more bodies may be located on the substrate so as to be spaced apart from each other. Each body may include an insertion recess so that at least a portion of a reaction vessel can be inserted therein. The substrate and the bodies may be made of a thermally conductive material.

Abstract: Disclosed are a metal nanoparticle-magnetic particle complex, comprising a core comprising a magnetic particle, the first shell comprising metal nanoparticles and formed on the surface of the core, and the second shell comprising a response factor and formed on the surface of the first shell, a method of preparing the complex, and a method of measuring the concentration of a biomarker in a sample using the complex.

Abstract: Mitochondria modified by a targeting protein, according to one embodiment of the present invention, can be effectively delivered to a target. In addition, when a protein of interest bound to the modified mitochondria is delivered into a cell, various activities can be exhibited. The modified mitochondria can effectively cause cancer tissue death, and thus can also be used as an anticancer agent. Furthermore, various activities are exhibited according to a protein of interest loaded on modified mitochondria, and thus the modified mitochondria can be applied in the treatment of various diseases. Additionally, a fusion protein comprising a protein of interest and a fusion protein comprising a targeting protein, according to one embodiment of the present invention, can be used in order to modify mitochondria. Moreover, mitochondria modified with the fusion proteins exhibits various effects in a target cell.