Abstract: A multi-electrode renal denervation method and system using an integrated circuit are provided. The multi-electrode renal denervation system presented in the present invention comprises: a power generator transmitting control data for controlling the temperature of a plurality of electrodes; and a catheter in which the plurality of electrodes, which has an integrated circuit embedded therein and is controlled by the control data received from the power generator, are arranged, and the information measured using the integrated circuit is transmitted to the power generator.

Abstract: A multi-electrode renal denervation method and system using an integrated circuit are provided. The multi-electrode renal denervation system presented in the present invention comprises: a power generator transmitting control data for controlling the temperature of a plurality of electrodes; and a catheter in which the plurality of electrodes, which has an integrated circuit embedded therein and is controlled by the control data received from the power generator, are arranged, and the information measured using the integrated circuit is transmitted to the power generator.

Abstract: A method of performing high-throughput screening of various enzymatic activities with high sensitivity using artificial genetic circuits is provided. Particularly, the invention is screening and quantifying the activity of isoprene biosynthesis enzymes using an artificial genetic circuit capable of sensing isoprene. The artificial genetic circuit comprises an isoprene-sensing transcriptional regulator which recognizes isoprene, at least one reporter gene, a isoprene-sensing transcriptional regulator binding region and promoters for genes encoding isoprene-sensing transcriptional regulators and reporter proteins. The artificial genetic circuit detects isoprene liberated from many enzymatic reactions and measures the activity of reporter genes. This system is widely applicable for high throughput and quantitative screening of isoprene biosynthesis enzymes and MEP/MVA pathway enzymes. Therefore, the invention can be advantageously used in the protein engineering technology for enzyme modification.

Abstract: A method of performing high-throughput screening of various enzymatic activities with high sensitivity using artificial genetic circuits is provided. Particularly, the invention is screening and quantifying the activity of isoprene biosynthesis enzymes using an artificial genetic circuit capable of sensing isoprene. The artificial genetic circuit comprises an isoprene-sensing transcriptional regulator which recognizes isoprene, at least one reporter gene, a isoprene-sensing transcriptional regulator binding region and promoters for genes encoding isoprene-sensing transcriptional regulators and reporter proteins. The artificial genetic circuit detects isoprene liberated from many enzymatic reactions and measures the activity of reporter genes. This system is widely applicable for high throughput and quantitative screening of isoprene biosynthesis enzymes and MEP/MVA pathway enzymes. Therefore, the invention can be advantageously used in the protein engineering technology for enzyme modification.