Abstract: This invention relates to a stilbene derivative and a method of preparing the same, and more particularly to a novel stilbene derivative for inhibiting the function of cyclophilin, which is effective at the prevention of cyclophilin-related diseases or at the treatment of symptoms of such diseases, and to a method of preparing the same.

Abstract: Novel intron fragments are provided. The intron fragments can increase gene expression to levels equal to or higher than those achieved by the full-length intron while maintaining their ability to increase gene expression even when combined with various types of promoters and splicing donors. Particularly, the intron fragments enable loading of larger transgenes when used in genetic information delivery systems whose size is limited, for example, adeno-associated viruses (AAVs) and rhabdoviruses. Therefore, the use of the intron fragments is expected to extend the range of therapeutic genes.

Abstract: A superconducting qubit-based device includes: a superconducting qubit comprising a first conductive pad and a second conductive pad, each being formed of a superconducting material, and a ferromagnetic body configured to form a Josephson junction with the first conductive pad and the second conductive pad; a conducting wire spaced apart from the ferromagnetic body by a predetermined distance; and a control circuit configured to control a resonance frequency of the superconducting qubit by controlling a current flowing through the conducting wire.

Abstract: In an embodiment a shape-transformable switch apparatus includes an electromagnet arranged inside a housing, wherein the electromagnet has an outer circumferential surface wound with a solenoid coil and is configured to provide a magnetic field when a power is applied to the solenoid coil, a Magnetorheological Elastomer (MRE) disposed on an upper portion of the electromagnet, wherein the MRE is configured to change from an initial soft state to a relatively hard state when the power is applied to the solenoid coil and configured to be pressed and to move upward when the electromagnet moves upward and a switch cover disposed on an upper portion of the housing, the switch cover configured to form a switch shape and to protrude outward when the MRE moves in an upward direction.

Abstract: A semiconductor memory device with improved integration and electrical characteristics. The semiconductor memory device includes a peri-gate structure, a first peri-connecting structure on the peri-gate structure, a data storage pattern on the first peri-connecting structure, an active pattern that includes a first surface and a second surface opposite to each other in a first direction, and a first side wall and a second side wall opposite to each other in a second direction, the first surface of the active pattern connected to the data storage pattern and facing a substrate, a bit line on the active pattern, connected to the second surface of the active pattern, and extends in the second direction, a word line on the first side wall of the active pattern and extending in a third direction, a second peri-connecting structure connected to the bit line and a connecting pad connected to the second peri-connecting wiring.

Abstract: A semiconductor memory device includes a peri-gate structure on a substrate, a first bonding pad on the peri-gate structure, a shielding conductive pattern on the first bonding pad, a second bonding pad between the shielding conductive pattern and the first bonding pad and contacting the first bonding pad, a bit line on the shielding conductive pattern extending in a first direction, an active pattern on the bit line and including a lower surface and an upper surface, and a first side wall and a second side wall opposite to each other in the first direction, the lower surface of the active pattern being connected to the bit line, a word line on the first side wall of the active pattern, and extends in a third direction, and a data storage pattern on the active pattern, and is connected to the upper surface of the active pattern.

Abstract: A semiconductor memory device including an active pattern on a first substrate and comprising a first and second surfaces opposite to each other in a first direction, a data storage pattern between the active pattern and the first substrate and connected to a first surface of the active pattern, a bit line on the active pattern, connected to a second surface of the active pattern, and extending in a second direction, a word line on a sidewall of the active pattern, a second substrate, a peripheral gate structure on a first surface of the second substrate, a first connection wiring structure on the first surface of the second substrate and connected to the peripheral gate structure and bit line, a second connection wiring structure on a second surface of the second substrate and a through via penetrating the second substrate and connecting the first and second connection wiring structures.

Abstract: Disclosed are a pharmaceutical composition for animals containing 5-hydroxy-1-methylimidazolidine-2,4-dione as an active ingredient, more specifically, a composition for preventing or treating kidney disease in animals containing 5-hydroxy-1-methylimidazolidine-2,4-dione or a pharmaceutically acceptable salt thereof as an active ingredient, a method of treating kidney disease in animals using the compound, and a functional feed for preventing or ameliorating kidney disease in animals containing the compound as an active ingredient. The 5-hydroxy-1-methylimidazolidine-2,4-dione can effectively ameliorate and treat symptoms of kidney disease when administered to companion animals such as dogs or cats with kidney disease. Therefore, there are provided a novel agent and method for treating kidney disease of animals that can effectively treat kidney disease, which is the cause of high mortality in companion animals.

Abstract: Disclosed is a percutaneous absorption formulation containing melatonin which is a pharmacologically active substance useful for treating insomniac patients and sleep disorder patients.

Abstract: An apparatus for tilting a seat cushion of a rear seat of a vehicle includes: a fixing member connected to a vehicle body and being shaft-rotated while a location of the fixing member is fixed; a tilting motor coupled to the fixing member; and a linkage connecting the tilting motor and the seat cushion of the seat, and operable to move a front end of the seat cushion vertically when the tilting motor is moved. The front end of the seat may be moved vertically so as to implement a tilting function, and a tilting apparatus of the rear seat may be operated simultaneously with occurrence of a collision or immediately before a collision so as to adjust the front end of the seat cushion upward, so that movement of a passenger in an accident can be restricted.

Abstract: Disclosed are a Mach-Zehnder interferometric optical modulator and a method for manufacturing the same. The modulator includes first and second lower clad layers, a core layer, an upper clad layer, a waveguide, and electrodes. The waveguide may include an input waveguide, a waveguide divider, branch waveguides, and a waveguide combiner. Each of the branch waveguides includes first and second connection regions connected to the waveguide combiner and the waveguide divider, respectively, and a phase shift region having a cross-section of a reverse mesa structure that has an upper width that is the same as widths of the first and second connection regions and a lower width that is smaller than the widths of the first and second connection regions.

Abstract: The present invention provides a polyurethane foam and a manufacturing method therefor, the polyurethane foam being a reaction product of a polyester polyol and an isocyanate and having a flame retardancy index (FRI) of 130 or less, wherein the polyester polyol is formed from a composition comprising an alcohol and two or more types of aromatic carboxylic acid including isophthalic acid and phthalic acid. The polyurethane foam can have both improved flame retardancy and heat resistance, and has total heat release and total smoke release that are significantly lower than those of a conventional polyurethane foam, and thus has an excellent fire protection effect when used as an interior material for buildings and low toxic gas generation.

Abstract: An open space type headrest is applied to a vehicle seat in which a covering, which surrounds a foam pad of a volume body positioned on a mounting cover of a flat body coupled to a front surface of an exterior cover formed of a protrusion body, is fixed to the mounting cover, and opening spaces are formed in the exterior cover, the mounting cover, and the foam pad to enlarge front viewing of a rear passenger due to a see-through characteristic of a mesh fabric of the covering.

Abstract: A semiconductor nanoparticle, a production method, and an electroluminescent devices including the same, wherein the semiconductor nanoparticles include a zinc chalcogenide including zinc, selenium, and sulfur, the semiconductor nanoparticles do not include cadmium, the semiconductor nanoparticles exhibit a peak emission wavelength in a range of greater than or equal to about 455 nanometers (nm) and less than or equal to about 480 nm, in a photoluminescence spectroscopy analysis, the semiconductor nanoparticles exhibit an absolute quantum yield of greater than or equal to about 80% and a full width at half maximum of less than or equal to about 50 nm, and an average particle size of the semiconductor nanoparticles is greater than or equal to about 12 nm and less than or equal to about 50 nm.

Abstract: Disclosed are an oriented electrical steel sheet and a manufacturing method thereof. An exemplary embodiment of the present invention provides a method of manufacturing an oriented electrical steel sheet, including: providing a slab including Si at 1.0 to 4.0 wt %, C at 0.1 to 0.4 wt %, and the remaining portion including Fe and other inevitably incorporated impurities; reheating the slab; producing a hot rolled steel sheet by hot rolling the slab; performing annealing of the hot rolled steel sheet; cold rolling the annealed hot rolled steel sheet; decarburizing and primary annealing the cold rolled steel sheet; cold rolling the decarburized and annealed steel sheet; and secondary annealing the cold rolled steel sheet.

Abstract: The present invention relates to a battery manufacturing device including: a fixed roller that moves an electrode where an active material is applied; a roller that rolls the electrode; and a stopper that is disposed between the fixed roller and the roller, and when the electrode is disconnected, moves the disconnected electrode.

Abstract: A method of coating an active material for a secondary battery according to one embodiment of the present disclosure is a method of coating an active material on an electrode current collector of a secondary battery, the method comprising the steps of: disposing a guide member on each of the left and right sides based on a moving direction of the electrode current collector, and coating the active material onto the electrode current collector between the two guide members.

Abstract: The present invention relates to a haptic actuator based on a nutation structure using a squeeze mode of a magneto-rheological fluid, which compresses a magneto-rheological fluid (MR fluid) by using a rotary body capable of performing a rotary motion based on a nutation structure, thereby generating a sustainable rotational resistance force by using a squeeze mode and a flow mode of the MR fluid.

Abstract: An armrest for a rear center seat of a vehicle includes a foam pad for the rear armrest and a convenience device mounted in the foam pad. The foam pad has formed therein a concave portion configured to induce deformation due to impact and distribute load at a portion in contact with the convenience device so as to satisfy the static strength test on a center headrest for the rear center seat, and at the same time, improve comfort of a passenger seated on the rear center seat.

Abstract: An anode for a lithium metal battery and a lithium metal battery that contains an anode for a lithium metal battery, wherein 1) using an anode current collector including multiple holes that, independently from each other, form first pores on one side of a metal plate and form second pores having relatively larger diameters than the first pores on the other side of the metal plate, penetrate inside the metal plate, and connect the first pores and the second pores, and 2) a lithium metal layer that is formed so as to face the first pores of the anode current collector. Another embodiment of the present invention provides a lithium metal battery designed such that a separator faces the second pores (pores having relatively large diameters) of the anode current collector, using the anode for a lithium metal battery of one embodiment.