Abstract: The present invention relates to a composition for preventing or treating transplantation rejection or a transplantation rejection disease, comprising a novel compound and a calcineurin inhibitor. A co-administration of the present invention 1) reduces the activity of pathogenic Th1 cells or Th17 cells, 2) increases the activity of Treg cells, 3) has an inhibitory effect against side effects, such as tissue damage, occurring in the sole administration thereof, 4) inhibits various pathogenic pathways, 5) inhibits the cell death of inflammatory cells, and 6) increases the activity of mitochondria, in an in vivo or in vitro allogenic model, a transplantation rejection disease model, a skin transplantation model, and a liver-transplanted patient, and thus inhibits transplantation rejection along with mitigating side effects possibly occurring in the administration of a conventional immunosuppressant alone.

Abstract: According to various embodiments, a method for manufacturing a metal housing can be provided, comprising: a step of forming a metal base made of a metal material; a step of pretreating the surface of the metal base such that the surface has a predetermined gloss and flatness; an anodizing step of forming a predetermined oxide film on the flat surface of the metal base; a step of coloring the oxide film by using a colorant having a desired color; a sealing step for maintaining the performance and characteristics of the colorant on the colored oxide film; and a step of laminating at least one deposition layer on the upper part of the sealed oxide film.

Abstract: According to various embodiments, a method for manufacturing a metal housing can be provided, comprising: a step of forming a metal base made of a metal material; a step of pretreating the surface of the metal base such that the surface has a predetermined gloss and flatness; an anodizing step of forming a predetermined oxide film on the flat surface of the metal base; a step of coloring the oxide film by using a colorant having a desired color; a sealing step for maintaining the performance and characteristics of the colorant on the colored oxide film; and a step of laminating at least one deposition layer on the upper part of the sealed oxide film.

Abstract: According to various embodiments, there may be provided a housing manufacturing method including preparing a base material, disposing at least one patterned structure layer including a plurality of fillers on an upper portion of the base material, and disposing a protective layer on an upper portion of the patterned structure layer. In addition, the housing manufactured by the aforementioned manufacturing method may be applied to at least part of an exterior of an electronic device.