Abstract: Disclosed are a biological sample analysis system and method for determining whether or not each of a plurality of biological samples has a test-target property using the plurality of biological samples and a plurality of pools generated by pooling samples. The system includes a determiner configured to determine whether or not there is a possibility of a determination of a false positive according to test values for the test-target property of the plurality of pools, an additional sample selector configured to select a minimum number of additional test-target samples on which an individual test of whether or not a sample has the test-target property will be carried out from among the plurality of samples when it is determined that there is the possibility of a determination of a false positive, and a test result determiner configured to determine whether or not each of the plurality of samples has the test-target property according to test results of the additional test-target samples.

Abstract: Provided are a method and apparatus for accumulating positive frequency data. The method includes receiving result data of pooling tests performed on a plurality of pools on a two dimensional (2D) matrix, the pooling test result data including allele frequencies of positive pools for a standard variant, predicting the number of positive samples for the standard variant from the allele frequencies of the positive pools, calculating a positive frequency for the standard variant from the number of positive samples, and updating the positive frequency for the standard variant to positive frequency database.

Abstract: A method for detecting a pooling error including the steps of determining an expected number of normal chromosome strands of a plurality of samples contained in a first pool based on ploidy types of the plurality of samples, determining whether a number of normal chromosome strands is different from the expected number of chromosome strands determined based on base sequences of the plurality of samples contained in the first pool, determining whether pooling is equilibrated based on an allele frequency value for a standard variant of the first pool, and detecting a pooling error using results of the determining the number of normal chromosome strands and the determining whether the pooling is equilibrated.

Abstract: Provided are a method and apparatus for verifying pool test result. The method includes receiving pool test result data obtained by performing a pool test on a plurality of pools configured based on a two-dimensional (2D) matrix, the pool test result data including allele frequencies of the plurality of pools, extracting a pool-specific variant from the matrix using the allele frequencies determining whether there is an intersecting pool among pools intersecting, in the matrix, a pool showing the pool-specific variant and determining whether the pool test result data is erroneous based on results of the determining whether there is an intersecting pool.

Abstract: There are provided a system and method for analyzing a biological sample.

Abstract: Disclosed are a biological sample analysis system and method for determining whether or not each of a plurality of biological samples has a test-target property using the plurality of biological samples and a plurality of pools generated by pooling samples. The system includes a determiner configured to determine whether or not there is a possibility of a determination of a false positive according to test values for the test-target property of the plurality of pools, an additional sample selector configured to select a minimum number of additional test-target samples on which an individual test of whether or not a sample has the test-target property will be carried out from among the plurality of samples when it is determined that there is the possibility of a determination of a false positive, and a test result determiner configured to determine whether or not each of the plurality of samples has the test-target property according to test results of the additional test-target samples.