Abstract: The present invention relates to a composition for producing an extracellular matrix from a eukaryotic cell, the composition comprising a polypeptide or compound capable of specifically binding to a microtubule associated serine/threonine kinase family member 4 (MAST4) protein or a fragment thereof or a polynucleotide, polypeptide or compound capable of specifically binding to a nucleic acid coding for the MAST4 protein or a fragment thereof, and a composition for promoting chondrogenesis, comprising the same composition.

Abstract: The present invention provides a motor that comprises: a housing: a stator that is included in the housing and around which a coil is wound; a rotor coupled to the inside of the stator; a shaft coupled to the rotor; and a bus bar-terminal assembly that includes a bus bar that includes a connection terminal connected with the coil and a terminal connected with an external power supply and a body that includes the bus bar therein such that the connection terminal and the terminal protrude to the outside, wherein the bus bar-terminal assembly includes an alignment guide part provided on the outer circumferential surface of the body in the height direction and slide-coupled with the inner circumferential surface of the housing.

Abstract: A backside illuminated image sensor includes a substrate having a frontside surface, a backside surface and a recess formed in a backside surface portion thereof, pixel regions disposed in the substrate, an insulating layer disposed on the frontside surface of the substrate, a bonding pad disposed on a frontside surface of the insulating layer, an anti-reflective layer disposed on the backside surface of the substrate, and a second bonding pad disposed in the recess and electrically connected with the bonding pad. The anti-reflective layer includes a metal oxide layer disposed on the backside surface of the substrate, a first silicon insulating layer disposed on the metal oxide layer, and a second silicon insulating layer disposed on the first silicon insulating layer. The second silicon insulating layer includes a first portion disposed on an inner side surface of the recess and a second portion disposed on a bottom surface of the recess.

Abstract: A pixel of an image sensor, which is capable of resolving a depth error occurring in high-speed charge transfer, includes a detector including a plurality of doped regions configured to receive light and transfer generated electrons; and a demodulator configured to receive the electrons from the detector through a plurality of transfer gates and demodulate the electrons, wherein a first doped region from among the plurality of doped regions is doped to have a first pinning voltage, and a second doped region from among the plurality of doped regions is located adjacent to the first doped region and doped to have a second pinning voltage higher than the first pinning voltage, wherein the plurality of transfer gates is located adjacent to the second doped region.

Abstract: Disclosed is a motor including a housing having a first receiving part formed at one side thereof, a stator disposed in the housing, a rotor disposed in the housing, a rotating shaft rotated along with the rotor, a holder coupled to one side of the housing, and a bearing disposed between the first receiving part and the holder to support a rotation of the rotor.

Abstract: A semiconductor device including a test circuit is disclosed. The semiconductor device includes a test pad coupled to a probe of a test device during a wafer test; a normal pad configured to receive a power or a signal during a normal mode; and a test circuit configured to perform a predetermined test operation based on a test signal received through the test pad. The test circuit is disposed below the normal pad.

Abstract: The present invention relates to compounds represented by Formula 1 or a pharmaceutically acceptable salt thereof, wherein: R1 is chloro or methyl; R2 is hydrogen or chloro; R3 is hydrogen, fluoro, chloro, bromo, methyl, ethyl, isopropyl, pentyl, hexyl, octyl, methoxy, phenoxy, (4-nitrophenyl)sulfonyl, piperidin-4-yl, or piperazin-1-yl; R4 is hydrogen, chloro, methyl or trifluoromethyl, phenoxy, (4-nitrophenyl)sulfonyl or piperidin-4-yl; or R3 and R4, together with the carbons to which they are attached, form a fused ring selected form the group consisting of: n is 1 or 2. These compounds according to the present invention remarkably inhibits activity of DRAK that inhibits signal systems of TGF-?, which is known to suppress cancer growth, and thus the novel pyrimidine compounds can be used as a pharmaceutical composition for preventing or treating cancer and can be used as a pharmaceutical composition for preventing or treating inflammatory disease.

Abstract: A frequency detection circuit may include a pulse generator configured to generate a pulse signal having a pulse width proportional to a cycle of a periodic wave to be measured; a low pass filter configured to selectively allow the pulse signal to pass therethrough; and a determination circuit configured to generate a frequency detection signal based on the pulse signal having passed through the low pass filter.

Abstract: An embodiment of the present invention relates to a lighting device comprising: a light source unit comprising a plurality of light emitting elements; a conversion unit for converting light emitted from the light source unit; a reflection unit for reflecting light which has passed through the conversion unit; and a half mirror member, which is disposed on the top of the reflection unit, for transmitting a portion of incident light and reflecting a portion of the incident light. The conversion unit includes an optical pattern for selectively transmitting light emitted from the light source unit, the light source unit is disposed on a periphery portion of the reflection unit, and the height of the center portion of the reflection unit is greater than the height of the periphery portion thereof.

Abstract: Provided are a pharmaceutical composition for preventing or treating cancer and a method of preventing or treating cancer using the same. Cancer may be effectively prevented or treated using the pharmaceutical composition and method.

Abstract: Disclosed is a hydrophilic material oil fence having a double-porous mesh. The hydrophilic material oil fence having the double-porous mesh includes a floating body floating on a water surface, and a skirt coupled to an upper portion and a lower portion of the floating body and made of a hydrophilic material through which a hydrophilic fluid selectively passes. A mesh hole size of a partial region of the skirt and a mesh hole size of the other region of the skirt are different.

Abstract: A nonvolatile memory device including a memory cell array having a plurality of planes; a plurality of page buffers arranged corresponding to each of the plurality of planes; and a control logic circuit configured to transmit a bit line setup signal to each of the plurality of page buffers. Each of the plurality of page buffers includes a precharge circuit configured to precharge a sensing node and a bit line in response to the bit line setup signal, and a shutoff circuit configured to perform a bit line shutoff operation in response to a bit line shutoff signal. The control logic circuit is configured to control a transition time when a level of the bit line setup signal is changed according to a gradient of the bit line shutoff signal which is changed from a first level to a second level.

Abstract: An embodiment of the present invention relates to a lighting device comprising: a light source unit comprising a plurality of light emitting elements; a conversion unit for converting light emitted from the light source unit; a reflection unit for reflecting light which has passed through the conversion unit; and a half mirror member, which is disposed on the top of the reflection unit, for transmitting a portion of incident light and reflecting a portion of the incident light. The conversion unit includes an optical pattern for selectively transmitting light emitted from the light source unit, the light source unit is disposed on a periphery portion of the reflection unit, and the height of the center portion of the reflection unit is greater than the height of the periphery portion thereof.

Abstract: A lighting device according to one embodiment comprises: a housing having an opening; a half mirror member arranged in the opening; a first light source unit for emitting light at the half mirror member; a mirror member for re-reflecting light reflected by the half mirror member; a diffusion plate arranged between the first light source unit and the half mirror member; and a guide unit protruding from the lower surface of the housing, wherein the housing includes a first area and a second area formed by the guide unit, the first light source unit is arranged in the first area and the mirror member is arranged in the second area, and the diffusion plate can be supported by the guide unit. Therefore, the lighting device can implement various three-dimensional effects of an optical image according to a field of view by using the half mirror member and the mirror member during lighting.

Abstract: An embodiment provides a lighting device comprising: a conversion unit including an optical layer having a plurality of optical patterns; a light emitting element for emitting light toward the optical patterns; and a circuit board on which the light emitting element is disposed, wherein the plurality of optical patterns are spaced apart from each other in a first direction and extend in a second direction intersecting the first direction, and the optical layer has a curvature in the first direction.

Abstract: An embodiment of the present invention relates to a lighting device comprising: a light source unit comprising a plurality of light emitting elements; a conversion unit for converting light emitted from the light source unit; a reflection unit for reflecting light which has passed through the conversion unit; and a half mirror member, which is disposed on the top of the reflection unit, for transmitting a portion of incident light and reflecting a portion of the incident light. The conversion unit includes an optical pattern for selectively transmitting light emitted from the light source unit, the light source unit is disposed on a periphery portion of the reflection unit, and the height of the center portion of the reflection unit is greater than the height of the periphery portion thereof.

Abstract: The present disclosure relates to a method of diagnosing metastatic cancer or taxane-based drug-resistant cancer, including: measuring an LMCD1 expression level from a complex formed by bringing, into contact with a sample isolated from a subject, an antibody, peptide, protein, or combination thereof that specifically binds to an LMCD1 protein or a fragment thereof; or a probe, primer, nucleotide, or combination thereof that specifically binds to a nucleotide sequence encoding the LMCD1 protein; and comparing the measured LMCD1 expression level of the sample with a measured LMCD1 expression level of a control, and a kit for diagnosing metastatic cancer or taxane-based drug-resistant cancer, including a composition for diagnosing metastatic cancer or taxane-based drug-resistant cancer.

Abstract: The present invention relates to a motor and a brake device including the same, wherein the motor including: a rotary shaft; a rotor part in which the rotary shaft is disposed at the center thereof; a stator part disposed on the outside of the rotor part; a housing accommodating the rotor part and the stator part, and having an opening formed at one side thereof; and a motor cover disposed at the opening of the housing, wherein the motor cover includes: a motor cover body; a first protruding part and a second protruding part, which are each formed at a predetermined location and configured to protrude in the radial direction from the center of the motor cover body; and a third protruding part formed to protrude from an edge of the motor cover body, and a sealing part is further disposed between the second protruding part and the end portion of the housing disposed between the second protruding part and the third protruding part.

Abstract: Disclosed herein is a sealing cover. The sealing cover includes a cap, a grommet configured to extend from the cap, and a terminal inserted into the grommet, wherein the grommet includes a groove formed to be recessed and having the terminal inserted therein. Advantageous effects are provided such that a process for assembly is simplified and flexibility of terminals is secured.

Abstract: An embodiment of the present invention relates to a lighting device comprising: a light source unit comprising a plurality of light emitting elements; a conversion unit for converting light emitted from the light source unit; a reflection unit for reflecting light which has passed through the conversion unit; and a half mirror member, which is disposed on the top of the reflection unit, for transmitting a portion of incident light and reflecting a portion of the incident light. The conversion unit includes an optical pattern for selectively transmitting light emitted from the light source unit, the light source unit is disposed on a periphery portion of the reflection unit, and the height of the center portion of the reflection unit is greater than the height of the periphery portion thereof.