Abstract: A self-circularization RNA construct that can be expressed in a DNA vector and simultaneously circularized through a self-targeting and splicing reaction to form a circRNA is disclosed. The circRNA can consist only of a gene of interest which can be a coding, non-coding, or a combination thereof. The gene of interest has the advantage of being able to rapidly express a peptide or protein. The formed circRNA has a circular structure and has a stable and high half-life because 5? and 3? ends are not exposed. Accordingly, functional RNA such as miRNA, anti-miRNA, siRNA, shRNA, aptamer, functional RNA for gene/RNA editing, ADAR (adenosine deaminase acting on the RNA)-recruiting RNA, mRNA vaccine, mRNA therapeutic agent, vaccine adjuvant, and CAR-T mRNA can be produced as a stable circRNA in cells.

Abstract: Provided herein is an immunocytokine comprising (i) an antigen binding protein (ABP) specific to a target protein; (ii) an IL-21 domain; and (iii) an IL-21R? mutein, wherein the IL-21R? mutein has a reduced binding affinity to the IL-21 domain compared to a wild-type IL-21R?. Further provided includes a method of using the immunocytokine to selectively activate an IL-21R? on a target cell, thereby enhance immune response or treat cancer.

Abstract: A trans-splicing ribozyme capable of splicing a rhodopsin transcript at a target splicing site and containing a sequence that is capable of complementarily binding to a target binding site of the rhodopsin transcript is disclosed. The trans-splicing ribozyme may further containing a desired rhodopsin transcript at 3?-end. The trans-splicing ribozyme may further contains an antisense sequence that is complementary to a region downstream the target binding site of the rhodopsin transcript. A nucleotide molecule encoding the trans-splicing ribozyme is also disclosed. Delivery systems to delivery the nucleotide molecule and/or the trans-splicing ribozyme to target tissue or cells as well as uses of the trans-splicing ribozyme, the nucleotide molecule, delivery systems, or pharmaceutical compositions containing any of them are also disclosed.

Abstract: A trans-splicing ribozyme capable of splicing a rhodopsin transcript at a target splicing site and containing a sequence that is capable of complementarily binding to a target binding site of the rhodopsin transcript is disclosed. The trans-splicing ribozyme may further containing a desired rhodopsin transcript at 3?-end. The trans-splicing ribozyme may further contains an antisense sequence that is complementary to a region downstream the target binding site of the rhodopsin transcript. A nucleotide molecule encoding the trans-splicing ribozyme is also disclosed. Delivery systems to delivery the nucleotide molecule and/or the trans-splicing ribozyme to target tissue or cells as well as uses of the trans-splicing ribozyme, the nucleotide molecule, delivery systems, or pharmaceutical compositions containing any of them are also disclosed.

Abstract: A cancer-specific trans-splicing ribozyme and a use thereof are disclosed. The trans-splicing ribozyme does not act on normal tissue, but is specifically expressed in cancer tissue. Therefore, it is very safe and has excellent expression efficiency at the post-transcription level, and thus can be effectively used in treatment of cancer.

Abstract: A method and an apparatus for estimating direction of arrival of radar reception signal using antenna array extrapolation. Obtained is a transformation matrix representing a relationship between phases of reception signals received through ith to (N?2+i)th antennas and a phase of a reception signal received through (N?1+i)th antenna in a ULA antenna unit including N actual antennas. A phase of a virtual reception signal received through a new (N+i)th virtual antenna is generated by multiplying values corresponding to phases of the reception signals received through (i+1)th to (N?1+i)th antennas by the transformation matrix. A magnitude of the virtual reception signal received through the (N+i)th virtual antenna is obtained by averaging magnitudes of the reception signals received through ith to (N?1+i)th antennas.

Abstract: Disclosed is a resolver, which includes a stator having at least one excitation coil and at least one output coil, and a rotor disposed at a center space in the stator with a predetermined gap from the stator, the rotor rotating based on a rotary shaft to change a gap permeance with respect to the stator, wherein an area ratio (Ar/As) between the stator and the rotor satisfies Equation 1 below to prevent magnetic saturation of the resolver, improve measurement precision and reduce manufacture costs without increasing a size or weight of the resolver: 0.22?Ar/As?0.37??Equation 1 where As represents a sectional area of the stator, and Ar represents a sectional area of the rotor.

Abstract: The present invention relates to a compound having a bis phenylene group substituted with alkylamide, a composition comprising the same for the control of polyphenylene polymer flowability and a method for controlling polyphenylene polymer flowability using the same. The said compound can improve the flowability of polyphenylene polymer so that it can be used for processing polyphenylene polymer to improve the flowability, thereby providing economic benefits by diversifying PPS parts and improving workability. In addition, the said compound can control and improve the flowability by regulating the length of phenyl-conjugated alkyl, so that it can be effectively used as a flowability regulator of polyphenylene polymer particularly polyphenylene sulfide.

Abstract: A wireless power transmitter configured to wirelessly transmit power to an electronic device is provided.

Abstract: A cancer-specific trans-splicing ribozyme and a use thereof are disclosed. The trans-splicing ribozyme does not act on normal tissue, but is specifically expressed in cancer tissue. Therefore, it is very safe and has excellent expression efficiency at the post-transcription level, and thus can be effectively used in treatment of cancer.

Abstract: Disclosed is a resolver, which includes a stator made of a magnetic material and having a plurality of teeth and a plurality of slots alternately formed at an inner side thereof; insulation covers respectively having a tooth insulating unit formed at an inner side thereof corresponding to the teeth and mounted to the stator at both upper and lower surfaces of the stator; and coils wound on the teeth with the tooth insulating unit being interposed therebetween, wherein a coil occupying ratio per slot, which is defined by the following equation and represents a ratio of area occupied by the coils in a slot to which the insulation covers are fixed, is 35% or below: Coil occupying ratio per slot=(area occupied by coils in a single slot)/(area of a single slot)??Equation.

Abstract: Disclosed is a resolver robust against external noise and having a reduced error in the detection of a rotation angle, which includes a stator made of a magnetic material and having a plurality of teeth and a plurality of slots alternately formed at an inner side thereof, insulation covers respectively having a tooth insulating unit formed at an inner side thereof corresponding to the teeth and mounted to the stator at both upper and lower surfaces of the stator, and coils wound on the teeth with the tooth insulating unit being interposed therebetween, wherein regarding winding widths of coils located at an outermost circumference among the wound coils, a ratio of a shortest winding width to a longest winding width is 0.69 or above and 1 or below.

Abstract: Disclosed is a resolver, which includes a stator having at least one excitation coil and at least one output coil, and a rotor disposed at a center space in the stator with a predetermined gap from the stator, the rotor rotating based on a rotary shaft to change a gap permeance with respect to the stator, wherein the stator includes a back yoke having a ring-shaped body, and a plurality of teeth formed at an inner circumference of the back yoke so that the excitation coil and the output coil are wound thereon, wherein the rotor includes a ring-shaped body having a center hole into which the rotary shaft is inserted, and a plurality of salient poles formed at an outer circumference of the ring-shaped body.

Abstract: The present invention relates to a recombinant vector, characterized by including a cytotoxic T-lymphocyte-associated protein-4 (CTLA-4)-targeting trans-splicing ribozyme expression cassette for delivery of chimeric antigen receptor, wherein the expression cassette includes: (i) a CTLA-4-targeting trans-splicing ribozyme; and (ii) a polynucleotide encoding a chimeric antigen receptor ligated to the 3? exon of the ribozyme. The present invention also relates to a transformed cell into which the recombinant vector is introduced, a ribozyme expressed from the recombinant vector, a retrovirus expressing the ribozyme, and a T cell treated with the retrovirus.

Abstract: Disclosed is a resolver, which includes a stator having at least one excitation coil and at least one output coil, and a rotor disposed at a center space in the stator with a predetermined gap from the stator, the rotor rotating based on a rotary shaft to change a gap permeance with respect to the stator, wherein a thickness (tr) of the rotor and a thickness (ts) of the stator satisfies the equation: tr?ts?0.7 [mm], thereby efficiently offsetting an influence caused by an assembly error, which is commonly generated when assembling a resolver, improving the measurement precision, facilitating a resolver designing work and reducing manufacture costs.

Abstract: The present invention relates to a recombinant vector, characterized by including a cytotoxic T-lymphocyte-associated protein-4 (CTLA-4)-targeting trans-splicing ribozyme expression cassette for delivery of chimeric antigen receptor, wherein the expression cassette includes: (i) a CTLA-4-targeting trans-splicing ribozyme; and (ii) a polynucleotide encoding a chimeric antigen receptor ligated to the 3? exon of the ribozyme. The present invention also relates to a transformed cell into which the recombinant vector is introduced, a ribozyme expressed from the recombinant vector, a retrovirus expressing the ribozyme, and a T cell treated with the retrovirus.

Abstract: The present invention relates to a compound having a bis phenylene group substituted with alkylamide, a composition comprising the same for the control of polyphenylene polymer flowability and a method for controlling polyphenylene polymer flowability using the same. The said compound can improve the flowability of polyphenylene polymer so that it can be used for processing polyphenylene polymer to improve the flowability, thereby providing economic benefits by diversifying PPS parts and improving workability. In addition, the said compound can control and improve the flowability by regulating the length of phenyl-conjugated alkyl, so that it can be effectively used as a flowability regulator of polyphenylene polymer particularly polyphenylene sulfide.

Abstract: The present invention relates to a recombination vector, a transformation cell into which the recombinant vector is introduced, a ribozyme expressed from the recombination vector, a prophylactic or therapeutic composition for liver cancer comprising the recombination vector and the ribozyme, and a therapeutic method for liver cancer using the composition, said recombination vector comprising: a tissue-specific promoter; and a ribozyme-target gene expression cassette comprising a trans-splicing ribozyme targeting a cancer-specific gene and a target gene connected to the 3? exon of the ribozyme, wherein a splicing donor/splicing acceptor sequence (SD/SA sequence) is connected to the 5? end of the ribozyme-target gene expression cassette, woodchuck hepatitis virus posttranscriptional regulatory element (WPRE) is connected to the 3? end of the ribozyme-target gene expression cassette, and a nucleic acid sequence recognizing a micro RNA-122a (microRNA-122a, miR-122a) is further connected to the 3? end of the WPRE.

Abstract: Disclosed is a resolver, which includes a stator having at least one excitation coil and at least one output coil, and a rotor disposed at a center space in the stator with a predetermined gap from the stator, the rotor rotating based on a rotary shaft to change a gap permeance with respect to the stator, wherein a thickness (tr) of the rotor and a thickness (ts) of the stator satisfies the equation: tr?ts?0.7 [mm], thereby efficiently offsetting an influence caused by an assembly error, which is commonly generated when assembling a resolver, improving the measurement precision, facilitating a resolver designing work and reducing manufacture costs.

Abstract: A wireless power transmitter configured to wirelessly transmit power to an electronic device is provided.