Patents by Inventor Seongae YOON

Seongae YOON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds for selective histone deacetylase inhibitors, and pharmaceutical composition comprising the same
    Patent number: 9878986
    Abstract: Provided are urea derivatives of Formula I: with histone deacetylase (HDAC) inhibitory activity, optical isomers thereof, pharmaceutically acceptable salts thereof and pharmaceutical compositions comprising the same. The provided urea derivatives of Formula I are selective histone deacetylase (HDAC) inhibitors and are effective for the treatment of histone deacetylase-mediated diseases such as malignant tumors, inflammatory diseases, rheumatoid arthritis, and neurodegeneration.
    Type: Grant
    Filed: April 29, 2014
    Date of Patent: January 30, 2018
    Assignee: Chong Kun Dang Pharmaceutical Corp.
    Inventors: Changsik Lee, Hyun-Mo Yang, Hojin Choi, Dohoon Kim, Soyoung Kim, Nina Ha, Hyojin Lim, Eunhee Ko, Seongae Yoon, Daekwon Bae
  • NOVEL COMPOUNDS FOR SELECTIVE HISTONE DEACETYLASE INHIBITORS, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
    Publication number: 20170152230
    Abstract: The present invention relates to novel urea derivatives and, more particularly, to novel urea derivatives with histone deacetylase (HDAC) inhibitory activity, isomers thereof, pharmaceutically acceptable salts thereof, their use for the preparation of a medicaments comprising the same, a pharmaceutical composition comprising the same, a treatment method using the composition, and a method for preparing novel urea derivatives. The novel urea derivatives as selective histone deacetylase (HDAC) inhibitors are effective for the treatment of histone deacetylase-mediated diseases such as malignant tumors, inflammatory diseases, rheumatoid arthritis, neurodegeneration, etc.
    Type: Application
    Filed: April 29, 2014
    Publication date: June 1, 2017
    Inventors: Changsik LEE, Hyun-Mo YANG, Hojin CHOI, Dohoon KIM, Soyoung KIM, Nina HA, Hyojin LIM, Eunhee KO, Seongae YOON, Daekwon BAE
  • NOVEL COMPOUNDS FOR SELECTIVE HISTONE DEACETYLASE INHIBITORS, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
    Publication number: 20160083354
    Abstract: The present invention relates to novel urea derivatives and, more particularly, to novel urea derivatives with histone deacetylase (HDAC) inhibitory activity, isomers thereof, pharmaceutically acceptable salts thereof, their use for the preparation of a medicaments comprising the same, a pharmaceutical composition comprising the same, a treatment method using the composition, and a method for preparing novel urea derivatives. The novel urea derivatives as selective histone deacetylase (HDAC) inhibitors are effective for the treatment of histone deacetylase-mediated diseases such as malignant tumors, inflammatory diseases, rheumatoid arthritis, neurodegeneration, etc.
    Type: Application
    Filed: April 29, 2014
    Publication date: March 24, 2016
    Inventors: Changsik LEE, Hyun-Mo YANG, Hojin CHOI, Dohoon KIM, Soyoung KIM, Nina HA, Hyojin LIM, Eunhee KO, Seongae YOON, Daekwon BAE