Abstract: An embodiment heat pump system of a vehicle includes a first cooling device including a battery module and a first line for circulating a coolant, an air conditioner unit including a compressor, an internal condenser, a main heat exchanger, a first expansion valve, and an evaporator that are interconnected through a refrigerant line for circulating a refrigerant, and a chiller connected to the first cooling device through the first line, connected to the refrigerant line through a first connection line, and configured to adjust a coolant temperature through heat-exchanging a selectively introduced coolant with the refrigerant. The air conditioner unit further includes a second expansion valve, a first valve, a second valve, a second connection line, a third connection line, and a fourth connection line.

Abstract: An embodiment multi-way coolant valve includes an outer housing including first to third outer inlets, first to third outer outlets, and a pump mount portion coupled to one of the outer outlets, an inner housing rotatably provided within the outer housing and including penetration holes corresponding to the outer inlets and outlets, a coolant line defined by a selective connection of the penetration holes such that the outer inlets and outlets are selectively connected, pads interposed between an interior circumference of the outer housing and an exterior circumference of the inner housing at locations of the outer inlets and outlets, respectively, and a driving device connected to a rotation center of the inner housing to selectively rotate the inner housing within the outer housing, wherein the inner housing is configured to rotate by a preset interval according to a selected vehicle mode.

Abstract: A liquefied gas storage tank includes a corner block disposed on a corner portion, wherein the corner block includes a lower block, an upper block and an upper connecting block, the upper block includes a first inner fixing unit and a second inner fixing unit respectively provided inside a first surface and a second surface, bonded and connected to a secondary barrier, and each having a structure in which a primary inner plywood, a primary corner insulating material, and a primary outer plywood are stacked, and an inner bent portion installed at a corner spatial portion between the first inner fixing unit and the second inner fixing unit, and both side surfaces of the inner bent portion that are perpendicular to the secondary barrier each have a height reduced from a total height of each of the first and second inner fixing units.

Abstract: The liquefied gas storage tank includes a primary barrier, a primary insulation wall, a secondary barrier, and a secondary insulation wall. In a state where unit elements are arranged adjacent to each other, each of the unit elements being formed by stacking the secondary insulation wall, the secondary barrier, and a fixed insulation wall which is a part of the primary insulation wall, the primary insulation wall may comprise: a connection insulation wall provided in the space between the adjacent fixed insulation walls; first slits formed between the fixed insulation walls and the connection insulation wall when the connection insulation wall is inserted and installed between the adjacent fixed insulation walls; a plurality of second slits formed in a lengthwise direction and a widthwise direction of the fixed insulation walls; and a first insulating filler material for filling the first slits.

Abstract: Provided herein are methods of treating a cancer in a subject using a CLK inhibitor or pharmaceutically acceptable salt or solvate thereof.

Abstract: A suturing device for surgery according to the present invention includes: a body unit; a pair of suturing operation units which are supported by a frontal end of the body unit and are rotated between a first mode, in which the pair of suturing operation units are tooth-engaged to each other with a suture area therebetween so that a suturing needle supported by any one of the pair of suturing operation units penetrates through the suture area and is transferred to the other suturing operation unit, and a second mode, in which the suturing needle supported by the other suturing operation unit in the first mode is transferred to any one of the pair of suturing operation units; and a driving unit for providing a driving force to at least one of the pair of suturing operation units so that the pair of suturing operation units are rotated between the first mode and the second mode.

Abstract: A closed loop-type hemostatic device having built-in inner pincers which integrates holding type pincers with a device for fitting a hemostatic clip, so as to: primarily, find and temporarily perform hemostasis on a bleeding portion by using holding type pincers after confirming that the bleeding portion exists; secondarily, move a clip pressing part and a clip pressing part and enclose the bleeding portion; and then move only the clip pressing part and clip a closed loop-type hemostatic clip onto the bleeding portion so as to perform hemostasis. The amount of bleeding can be reduced by temporary hemostasis on a bleeding portion, and a hemostatic clip can be precisely clipped on the bleeding portion, thereby improving hemostatic performance. Also, because hemostasis can be selectively performed only around a damaged blood vessel wall, therefore, the physiological benefit of being able to maintain partial blood flow may be provided.

Abstract: A suturing device for surgery according to the present invention comprises: a body unit; a pair of suturing operation units which are supported by a frontal end of the body unit and are rotated between a first mode, in which the pair of suturing operation units are tooth-engaged to each other with a suture area therebetween so that a suturing needle supported by any one of the pair of suturing operation units penetrates through the suture area and is transferred to the other suturing operation unit, and a second mode, in which the suturing needle supported by the other suturing operation unit in the first mode is transferred to any one of the pair of suturing operation units; and a driving unit for providing a driving force to at least one of the pair of suturing operation units so that the pair of suturing operation units are rotated between the first mode and the second mode.

Abstract: A closed loop-type hemostatic device having built-in inner pincers which integrates holding type pincers with a device for fitting a hemostatic clip, so as to: primarily, find and temporarily perform hemostasis on a bleeding portion by using holding type pincers after confirming that the bleeding portion exists; secondarily, move a clip pressing part and a clip pressing part and enclose the bleeding portion; and then move only the clip pressing part and clip a closed loop-type hemostatic clip onto the bleeding portion so as to perform hemostasis. The amount of bleeding can be reduced by temporary hemostasis on a bleeding portion, and a hemostatic clip can be precisely clipped on the bleeding portion, thereby improving hemostatic performance. Also, because hemostasis can be selectively performed only around a damaged blood vessel wall, therefore, the physiological benefit of being able to maintain partial blood flow may be provided.

Abstract: Provided is a surgical instrument which can provide a field of view over a surgical site by sucking blood from a bleeding site during surgery on body tissue of a patient and monitoring a dark and deep surgical site, which an operator cannot see with his or her naked eye, with a small camera. The surgical instrument has substantially the same shape as a pair of scissors and includes a first body, a second body having a shape symmetrical to that of the first body, a hinge to which the first and second bodies cross and are rotatably coupled, and a photographing unit provided in the hinge to photograph a surgical site between front ends of the first and second bodies. The photographing unit may include a camera mounted in the hinge such that lens of the camera can be exposed through the center of the front surface of the hinge and configured to transmit a photographed image data to a monitor.

Abstract: Provided are a hemostatic clip and a hemostatic clip operation apparatus using the same that can rapidly stop bleeding from a bleeding area of a blood vessel when a middle or large diameter blood vessel partially bleeds during an abdominal operation or a surgery using an endoscope. The hemostatic clip operation apparatus includes a handle, a first gripper configured to primarily stop bleeding from a bleeding area of a blood vessel, a second gripper configured to receive the first gripper and symmetrically bend a closed-loop shaped-hemostatic clip to secondarily clip a periphery of the bleeding area stopped by the first gripper, and a gripper driver configured to connect the handle to the first and second grippers to be interlocked with operation of the handle to operate sequential stopping of bleeding and clipping of the first and second grippers.

Abstract: Provided is surgical instrument which can provide a field of view over surgical site by sucking blood from bleeding site during surgery on body tissue of patient and monitoring dark and deep surgical site, which operator cannot see with his or her naked eye, with small camera. The surgical instrument has substantially the same shape as a pair of scissors and includes first body, second body having shape symmetrical to that of the first body, hinge to which the first and second bodies cross and are rotatably coupled, and photographing unit provided in the hinge to photograph a surgical site between front ends of the first and second bodies. The photographing unit may include camera mounted in the hinge such that lens of the camera can be exposed through the center of the front surface of the hinge and configured to transmit photographed image data to monitor.

Abstract: Provided is a surgical instrument which can provide a field of view over a surgical site by sucking blood from a bleeding site during surgery such as tissue dissection and illuminating a dark and deep surgical site. The surgical instrument includes a first body including at least one suction port provided at a front end thereof, a second body configured to cross the first body and to be rotatably coupled to the first body, a suction unit provided in the first body to suck blood from a bleeding site of a patient through the suction port during surgery, and an illuminator provided in the second body to illuminate a space between front ends of the first and second bodies.