Patents by Inventor Sepehr Sarshar

Sepehr Sarshar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted amino alcohols
    Patent number: 7767860
    Abstract: Disclosed herein are substituted amino alcohol anti-mycobacterial agents and/or chelation therapy agents of Formula I, process of preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Grant
    Filed: September 3, 2008
    Date of Patent: August 3, 2010
    Assignee: Auspex Pharmaceuticals, Inc
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • DIBENZO[b,e][1,4]DIAZEPINE MODULATORS OF DOPAMINE RECEPTORS, SEROTONIN RECEPTORS, ADRENERGIC RECEPTORS, ACETYLCHOLINE RECEPTORS, AND/OR HISTAMINE RECEPTORS
    Publication number: 20100166887
    Abstract: The present invention relates to new dibenzo[b,e][1,4]diazepine modulators of dopamine receptors, serotonin receptors, adrenergic receptors, acetylcholine receptors, and/or histamine receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: October 21, 2009
    Publication date: July 1, 2010
    Applicant: Auspex Pharmaceuticals, Inc.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • Substituted phenethylamines
    Patent number: 7745665
    Abstract: Disclosed herein are substituted phenethylamine alpha adrenergic receptor modulators of Formula I, process of preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Grant
    Filed: June 3, 2008
    Date of Patent: June 29, 2010
    Assignee: Auspex Pharmaceuticals, Inc.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • 3,4-DIMETHOXYPHENETHYLAMINE MODULATORS OF L-TYPE CALCIUM CHANNEL
    Publication number: 20100160446
    Abstract: The present invention relates to new 3,4-dimethoxyphenethylamine modulators of L-type calcium channel activity, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: December 18, 2009
    Publication date: June 24, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • BENZENESULFONAMIDE MODULATORS OF ALPHA-1A ADRENERGIC RECEPTORS
    Publication number: 20100160338
    Abstract: The present invention relates to new benzenesulfonamide modulators of alpha-1A adrenergic receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: December 18, 2009
    Publication date: June 24, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • PYRROLIDINONE INHIBITORS OF PDE-4
    Publication number: 20100159034
    Abstract: The present invention relates to new pyrrolidinone inhibitors of PDE-4 activity, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: December 15, 2009
    Publication date: June 24, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • DIAMINOQUINAZOLINE INHIBITORS OF DIHYDROFOLATE REDUCTASE
    Publication number: 20100150896
    Abstract: The present invention relates to new diaminoquinazoline inhibitors of dihydrofolate reductase activity, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: December 11, 2009
    Publication date: June 17, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • PYRAZOLINONE SCAVENGERS OF FREE RADICAL
    Publication number: 20100150899
    Abstract: The present invention relates to new pyrazolinone scavengers of free radicals, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: December 10, 2009
    Publication date: June 17, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • INDANONE INHIBITORS OF ACETYLCHOLINESTERASE
    Publication number: 20100143505
    Abstract: The present invention relates to new indanone inhibitors of acetylcholinesterase, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: December 9, 2009
    Publication date: June 10, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar, Manouchehr M. Shahbaz
  • CARBOXYLIC ACID INHIBITORS OF HISTONE DEACETYLASE, GABA TRANSAMINASE AND SODIUM CHANNEL
    Publication number: 20100143507
    Abstract: The present invention relates to new carboxylic acid inhibitors of histone deacetylase, GABA transaminase, and/or sodium channel activity, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: December 7, 2009
    Publication date: June 10, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • QUINAZOLINE INHIBITORS OF EGFR TYROSINE KINASE
    Publication number: 20100143295
    Abstract: The present invention relates to new quinazoline inhibitors of EGFR tyrosine kinase, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: December 4, 2009
    Publication date: June 10, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • AMINO ACID INHIBITORS OF PLASMIN
    Publication number: 20100144880
    Abstract: The present invention relates to new amino acid inhibitors of plasmin, pharmaceutical compositions thereof, and methods of use thereof
    Type: Application
    Filed: December 4, 2009
    Publication date: June 10, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • TRIAZINE DNA MODIFIERS
    Publication number: 20100143354
    Abstract: The present invention relates to new triazine DNA modifiers, pharmaceutical compositions thereof, and methods of use thereof
    Type: Application
    Filed: December 4, 2009
    Publication date: June 10, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • PHENYLPIPERIDINE MODULATORS OF mu-OPIOID RECEPTORS
    Publication number: 20100144657
    Abstract: The present invention relates to new phenylpiperidine modulators of opioid ?-receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: December 8, 2009
    Publication date: June 10, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • PREPARATION AND UTILITY OF HMG-COA REDUCTASE INHIBITORS
    Publication number: 20100137244
    Abstract: Chemical syntheses and medical uses of novel modulators of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase and diastereomeric mixtures of isomers, individual diastereomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, the chemical synthesis thereof, and the medical use of such compounds for the treatment and/or management of hypercholesterolemia, dyslipidemia, coronary artery disease, atherosclerosis, metabolic syndrome, a hyperproliferative disease such as colorectal cancer, prostate cancer, and melanoma, a neurodegenerative disease such as cerebral ischemia, Alzheimer's disease, and Parkinson's disease are described.
    Type: Application
    Filed: July 12, 2007
    Publication date: June 3, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • INDOLINONE MODULATORS OF DOPAMINE RECEPTOR
    Publication number: 20100130582
    Abstract: The present invention relates to new indolinone modulators of dopamine receptor, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 24, 2009
    Publication date: May 27, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • ETHANOLAMINE MODULATORS OF NMDA RECEPTOR AND MUSCARINIC ACETYLCHOLINE RECEPTOR
    Publication number: 20100130617
    Abstract: The present invention relates to new ethanolamine modulators of NMDA receptors and/or muscarinic acetylcholine receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 23, 2009
    Publication date: May 27, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • BENZISOXAZOLE MODULATORS OF D2 RECEPTOR AND/OR 5-HT2A RECEPTOR
    Publication number: 20100119624
    Abstract: The present invention relates to new benzisoxazole modulators of D2 receptors and/or 5-HT2A receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 17, 2009
    Publication date: May 13, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • 3H-BENZOOXAZOL-2-ONE MODULATORS OF D2 RECEPTOR AND/OR 5-HT1A RECEPTOR
    Publication number: 20100119622
    Abstract: The present invention relates to new 3H-benzooxazol-2-one modulators of D2 receptors and/or 5-HT1A receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 15, 2009
    Publication date: May 13, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar
  • IMIDAZOLYL MODULATORS OF 5-HT3 RECEPTORS
    Publication number: 20100119623
    Abstract: The present invention relates to new imidazolyl modulators of 5-HT3 receptors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 16, 2009
    Publication date: May 13, 2010
    Applicant: AUSPEX PHARMACEUTICALS, INC.
    Inventors: Thomas G. Gant, Sepehr Sarshar