Patents by Inventor Seppo Parhi

Seppo Parhi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detomidine hydrochloride crystallization method
    Patent number: 7728147
    Abstract: A method of isolating detomidine (I) hydrochloride as a crystalline salt is provided. The method comprises hydrogenating in the presence of a catalyst of compound of formula (II) in aqueous solution comprising hydrochloric acid, concentrating the solution by distillation, optionally adding hydrochloric acid to the concentrated solution, cooling the concentrated solution and recovering the crystallized detomidine hydrochloride.
    Type: Grant
    Filed: April 13, 2006
    Date of Patent: June 1, 2010
    Assignee: Orion Corporation
    Inventors: Arto Karjalainen, Seppo Parhi
  • Atipamezole hydrochloride crystallization method
    Patent number: 7642279
    Abstract: A method of isolating atipamezole hydrocloride as a crystalline salt is provided.
    Type: Grant
    Filed: June 16, 2006
    Date of Patent: January 5, 2010
    Assignee: Orion Corporation
    Inventors: Seppo Parhi, Arto Karjalainen
  • Detomidine Hydrochloride Crystallization Method
    Publication number: 20080287685
    Abstract: A method of isolating detomidine (I) hydrochloride as a crystalline salt is provided. The method comprises hydrogenating in the presence of a catalyst of compound of formula (II) in aqueous solution comprising hydrochloric acid, concentrating the solution by distillation, optionally adding hydrochloric acid to the concentrated solution, cooling the concentrated solution and recovering the crystallized detomidine hydrochloride.
    Type: Application
    Filed: April 13, 2006
    Publication date: November 20, 2008
    Inventors: Arto Karjalainen, Seppo Parhi
  • Atipamezole Hydrochloride Crystallization Method
    Publication number: 20080275252
    Abstract: A method of isolating atipamezole hydrochloride as a crystalline salt is provided.
    Type: Application
    Filed: June 16, 2006
    Publication date: November 6, 2008
    Inventors: Seppo Parhi, Arto Karjalainen
  • Process for preparing substituted imidazole derivatives and intermediates used in the process
    Patent number: 7223871
    Abstract: The invention relates to a process for preparing substituted imidazole derivatives of formula (I) and acid addition salts thereof in which formula Y is —CH2— or —CO—, R1 is H, halo or hydroxy, R2 is H or halo and R3 is H or lower alkyl, starting from a compound of formula (II) wherein Y, R1, R2 and R3 are as defined above. The invention also relates to intermediates and their preparation.
    Type: Grant
    Filed: January 8, 2004
    Date of Patent: May 29, 2007
    Assignee: Oy Juvantia Pharma Ltd.
    Inventors: Päivi Juujärvi, Seppo Parhi, Jaana Karjalainen
  • Method for the production of a phenolic substance from wood
    Patent number: 7153982
    Abstract: A method for the production of hydroxymatairesinol or a hydroxymatairesinol complex from wood, including the steps of a) extracting finely divided wood material with a polar solvent, b) optionally concentrating the extract by separating at least part of the solvent, c) adding to the extract an agent able to form a complex with hydroxymatairesinol, d) precipitating the hydroxymatairesinol complex, and optionally e) releasing the hydroxymatairesinol from the complex.
    Type: Grant
    Filed: November 15, 2002
    Date of Patent: December 26, 2006
    Assignee: Hormos Medical Corporation
    Inventors: Seppo Parhi, Mervi Puska, Arja Kalapudas, Helena Korte, Petri Hukka
  • Process for preparing substituted imidazole derivates and intermediates used in the process
    Publication number: 20060025465
    Abstract: The invention relates to a process for preparing substituted imidazole derivatives of formula (I) and acid addition salts thereof in which formula Y is —CH2— or —CO—, R1 is H, halo or hyodroxy, R2 is H or halo and R3 is H or lower alkyl, starting from a compound of formula (II) wherein Y, R1, R2 and R3 are as defined above. The invention also relates to intermediates and their preparation.
    Type: Application
    Filed: January 8, 2004
    Publication date: February 2, 2006
    Applicant: Oy Juvantia Pharma Ltd
    Inventors: Paivi Juujarvi, Seppo Parhi, Jaana Karjalainen
  • Method for the production of a phenolic substance from wood
    Publication number: 20040267029
    Abstract: This invention concerns a method for the production of hydroxymatairesinol or a hydroxymatairesinol complex from wood, comprising the steps of
    Type: Application
    Filed: April 19, 2004
    Publication date: December 30, 2004
    Inventors: Seppo Parhi, Mervi Puska, Arja Kalapudas, Helena Korte, Petri Hukka
  • Phospholamban inhibitors and a method for increasing coronary flow
    Patent number: 6265421
    Abstract: A method for obtaining direct dilatation of the coronary arteries by administering a therapeutically effective amount of a phospholamban inhibitor is described. Compounds which are effective in relieving the inhibitory effects of phospholamban on cardiac sarcoplasmic reticulum Ca2+-ATPase are also described.
    Type: Grant
    Filed: February 18, 1999
    Date of Patent: July 24, 2001
    Assignee: Orion Corporation
    Inventors: Jarmo Pystynen, Heimo Haikala, Petri Kaheinen, Juha Kaivola, Piero Pollesello, Ismo Ulmanen, Jukka Tenhunen, Carola Tilgmann, Eija Tiainen, Kari Lönnberg, Pentti Nore, Seppo Parhi, Arto Karjalainen, Jouko Levijoki