Patents by Inventor Seppo W. Langer

Seppo W. Langer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of accidental extravasation of anthracyclines
    Patent number: 6727253
    Abstract: The present invention relates to a method for pharmacological treatment of accidental extravasation of topoisomerase II poisons, such as anthracyclines. In particular, the invention relates to the use of a topo II catalytic inhibitor, such as the bisdioxopiperazine ICRF-187, for the treatment of an accidental extravasation of a topoisomerase II poison. A method for treatment of such extravasation of a topoisomerase poison such as the anthracyclines, daunorubicin, doxorubicin, epirubicin, or idarubicin is disclosed.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: April 27, 2004
    Assignee: Antianthra APS
    Inventors: Seppo W. Langer, Peter B. Jensen, Maxwell Sehested
  • Succinimide and maleimide derivatives and their use as topoisomerase II catalytic inhibitors
    Publication number: 20030032625
    Abstract: Maleimide and succinimide derivatives were found to be effective topoisomerase II catalytic inhibitors. Due to this property, the maleimide and succinimide derivatives were investigated for their use as cytostatic agents and thus in the treatment of cancer. The compounds of the invention can be used in combination treatments with other cytostatic agents, such as topoisomerase II poisons. The maleimide and succinimide derivatives, due to their effective topoisomerase II catalytic inhibitory activity, are also useful as extravasation agents, such as upon administration of a topoisomerase II poison.
    Type: Application
    Filed: March 29, 2002
    Publication date: February 13, 2003
    Applicant: Topo Target ApS
    Inventors: Peter Buhl Jensen, Birgitte Sokilde, Elisabeth Vang Carstensen, Seppo W. Langer, Andrew Creighton, Maxvell Sehested, Lars Hollund Jensen
  • Treatment of accidental extravasation of anthracyclines
    Publication number: 20020099057
    Abstract: The present invention relates to a method and a medicament for pharmacological treatment of accidental extravasation of topoisomerase II poisons such as anthracyclines. In particular, the invention relates to the use of a topo II catalytic nhibitor such as the bisdioxopiperazine ICRF-187 for the manufacture of a medicament for the treatment of an accidental extravasation of a topoisomerase II poison and a method for treatment of such extravasation of a topoisomerase poison such as the anthracyclines daunorubicin, doxorubicin, epirubicin, or idarubicin. In addition, the invention relates to a kit for such treatment.
    Type: Application
    Filed: June 29, 2001
    Publication date: July 25, 2002
    Inventors: Seppo W. Langer, Peter B. Jensen, Maxwell Sehested