Patents by Inventor Ser Yue LOO

Ser Yue LOO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for manipulating cell state transitions in cancer
    Patent number: 12667546
    Abstract: The present invention relates to a method of inducing mesenchymal-epithelial transition (MET) in a basal-like (or mesenchymal-like) cancer cell by contacting the cancer cell with an inducer of mesenchymal-epithelial transition for a time and under conditions sufficient to induce MET in the cell. Additionally, there is also provided a method of inhibiting epithelial-mesenchymal transition (EMT) of a cancer in a subject, the method comprising administering an inhibitor or regulator of lipid metabolism for a sufficient time and under conditions to inhibit epithelial mesenchymal transition (EMT) of the cancer in the subject.
    Type: Grant
    Filed: November 11, 2019
    Date of Patent: June 30, 2026
    Assignee: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
    Inventors: Wai Leong Tam, Ser Yue Loo, Li Ping Toh
  • METHODS FOR MANIPULATING CELL STATE TRANSITIONS IN CANCER
    Publication number: 20220008358
    Abstract: The present invention relates to a method of inducing mesenchymal-epithelial transition (MET) in a basal-like (or mesenchymal-like) cancer cell by contacting the cancer cell with an inducer of mesenchymal-epithelial transition for a time and under conditions sufficient to induce MET in the cell. Additionally, there is also provided a method of inhibiting epithelial-mesenchymal transition (EMT) of a cancer in a subject, the method comprising administering an inhibitor or regulator of lipid metabolism for a sufficient time and under conditions to inhibit epithelial mesenchymal transition (EMT) of the cancer in the subject.
    Type: Application
    Filed: November 11, 2019
    Publication date: January 13, 2022
    Inventors: Wai Leong TAM, Ser Yue LOO, Li Ping TOH