Abstract: A system and method to test integrity of an electricity power supply network in an aircraft is disclosed. The system comprises: a current injector for connection to an output point of one or more phase line forming a test circuit with an electricity generator, the current injector configured to inject a test signal through the electricity generator in the test circuit; a current measurement test probe for installation in the test circuit to measure intensity of the injected test signal current; and a processing unit to connect to the current measurement test probe and to a set of input and output current measurement probes associated with the phase line to acquire current intensity measurement signals output by the current measurement test probe and by the set of input and output current measurement probes, and to determine electricity indicators representative of the integrity of the electricity power supply network.

Abstract: Disclosed herein are boronate intermediates in the synthesis of antimicrobial compounds and the use and preparation thereof. Some embodiments relate to crystalline boronate salt derivatives and their use in the synthesis of therapeutic compounds.

Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to cyclic boronic acid ester derivatives and their use as therapeutic agents.

Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to 1 cyclic boronic acid ester derivatives and their use as therapeutic agents.

Abstract: The present invention relates to compositions, pharmaceutical compositions, and methods for preparing the same, comprising a tetracycline with improved stability and solubility. Some embodiments include a tetracycline with an excess of a divalent or trivalent cation.

Abstract: The present invention relates to compositions, pharmaceutical compositions, and methods for preparing the same, comprising a tetracycline with improved stability and solubility. Some embodiments include a tetracycline with an excess of a divalent or trivalent cation.

Abstract: The present invention relates to compositions, pharmaceutical compositions, and methods for preparing the same, comprising a tetracycline with improved stability and solubility. Some embodiments include a tetracycline with an excess of a divalent or trivalent cation.

Abstract: A system and method to test integrity of an electricity power supply network in an aircraft is disclosed. The system comprises: a current injector for connection to an output point of one or more phase line forming a test circuit with an electricity generator, the current injector configured to inject a test signal through the electricity generator in the test circuit; a current measurement test probe for installation in the test circuit to measure intensity of the injected test signal current; and a processing unit to connect to the current measurement test probe and to a set of input and output current measurement probes associated with the phase line to acquire current intensity measurement signals output by the current measurement test probe and by the set of input and output current measurement probes, and to determine electricity indicators representative of the integrity of the electricity power supply network.

Abstract: The present invention relates to compositions, pharmaceutical compositions, and methods for preparing the same, comprising a tetracycline with improved stability and solubility. Some embodiments include a tetracycline with an excess of a divalent or trivalent cation.

Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to 1 cyclic boronic acid ester derivatives and their use as therapeutic agents.

Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to 1 cyclic boronic acid ester derivatives and their use as therapeutic agents.

Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to 1 cyclic boronic acid ester derivatives and their use as therapeutic agents.

Abstract: A method for checking takeoff or landing parameters of an aircraft including a step of determining takeoff or landing parameters on the basis of a series of input conditions. The method includes steps of calculating regulatory data on the basis of determined takeoff or landing parameters; and of comparing the calculated regulatory data with predefined threshold values, with a view to establishing whether the determined takeoff or landing parameters are valid or invalid.

Abstract: Compounds of Formula I, their preparation and uses are described: wherein: M and V are cis to one another and MH is cytarabine; the 5? oxygen of said cytarabine is attached to the phosphorus; V is 4-pyridyl; and pharmaceutically acceptable prodrugs and salts thereof.

Abstract: Compounds of Formula I, their preparation and synthetic intermediates, and their use in the synthesis of prodrugs: wherein: V and L are trans relative to one another; V is selected from group consisting of carbocyclic aryl, substituted carbocyclic aryl, heteroaryl, and substituted heteroaryl; and L is a leaving group selected from the group consisting of halogen, alkyl sulfonate, aryloxy optionally substituted with 1-2 substituents, N-containing heteroaryl, and N-hydroxy-nitrogen containing heteroaryl; and salts thereof.

Abstract: Novel cyclic phosphoramidate prodrugs of drugs of formula I their use in delivery of drugs to the liver, their use in enhancing oral bioavailability, and their method of preparation are described.

Abstract: A method for checking takeoff or landing parameters of an aircraft comprises a step (E101) of determining takeoff or landing parameters on the basis of a series of input conditions. It additionally comprises the following steps: calculation (E103) of regulatory data on the basis of determined takeoff or landing parameters; and comparison (E104) of the calculated regulatory data with predefined threshold values, with a view to establishing whether the determined takeoff or landing parameters are valid or invalid. Use to ensure reliability of the determination of optimized takeoff or landing parameters.

Abstract: Compounds of Formula I, their preparation and uses are described: wherein: M and V are cis to one another and MH is cytarabine; the 5? oxygen of said cytarabine is attached to the phosphorus; V is 4-pyridyl; and pharmaceutically acceptable prodrugs and salts thereof.

Abstract: Compounds of Formula I, their preparation and synthetic intermediates, and their use in the synthesis of prodrugs: wherein: V and L are trans relative to one another; V is selected from group consisting of carbocyclic aryl, substituted carbocyclic aryl, heteroaryl, and substituted heteroaryl; and L is a leaving group selected from the group consisting of halogen, alkyl sulfonate, aryloxy optionally substituted with 1-2 substituents, N-containing heteroaryl, and N-hydroxy-nitrogen containing heteroaryl; and salts thereof.

Abstract: Compounds of Formula I, their preparation and uses are described: wherein: M and V are cis to one another and MH is cytarabine; the 5? oxygen of said cytarabine is attached to the phosphorus; V is 4-pyridyl; and pharmaceutically acceptable prodrugs and salts thereof.