Patents by Inventor Serge Grisoni

Serge Grisoni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Derivatives of macrocyclic N-aryl-tricyclopyrimidine-2-amine polyethers as inhibitors of FTL3 and JAK
    Patent number: 10323043
    Abstract: The present invention relates to a compound with the following formula (I): (I) or a salt and/or a pharmaceutically acceptable solvate thereof, in particular for use as a drug, in particular in the treatment of cancer, as well as to the pharmaceutical compositions that contain same and to the methods for preparing same.
    Type: Grant
    Filed: September 2, 2015
    Date of Patent: June 18, 2019
    Assignee: PIERRE FABRE MEDICAMENT
    Inventors: El Bachir Kaloun, Serge Grisoni, Anna Kruczynski, Philippe Schmitt
  • DERIVATIVES OF MACROCYCLIC N-ARYL-TRICYCLOPYRIMIDINE-2-AMINE POLYETHERS AS INHIBITORS OF FTL3 AND JAK
    Publication number: 20170283432
    Abstract: The present invention relates to a compound with the following formula (I): (I) or a salt and/or a pharmaceutically acceptable solvate thereof, in particular for use as a drug, in particular in the treatment of cancer, as well as to the pharmaceutical compositions that contain same and to the methods for preparing same.
    Type: Application
    Filed: September 2, 2015
    Publication date: October 5, 2017
    Applicant: PIERRE FABRE MEDICAMENT
    Inventors: El Bachir KALOUN, Serge GRISONI, Anna KRUCZYNSKI, Philippe SCHMITT
  • DERIVATIVES OF MACROCYCLIC N-ARYL-2-AMINO-4-ARYL-PYRIMIDINE POLYETHERS AS INHIBITORS OF FTL3 AND JAK
    Publication number: 20170281622
    Abstract: The present invention relates to a compound with the following formula: formula (I) or a salt and/or a pharmaceutically acceptable solvate thereof, in particular for use as a drug, in particular in the treatment of cancer, as well as to the pharmaceutical compositions that contain same and to the methods for preparing same.
    Type: Application
    Filed: September 2, 2015
    Publication date: October 5, 2017
    Applicant: PIERRE FABRE MEDICAMENT
    Inventors: El Bachir KALOUN, Serge GRISONI, Bruno GOMES, Philippe SCHMITT
  • GRISEOFULVIN DERIVATIVES
    Publication number: 20160289204
    Abstract: The present invention relates to compounds of the following general formula (I), or to a pharmaceutically acceptable salt thereof, as well as to the uses thereof as a drug, in particular for treating cancerous or precancerous hyperproliferative conditions, and to the pharmaceutical compositions containing same.
    Type: Application
    Filed: June 15, 2016
    Publication date: October 6, 2016
    Applicant: PIERRE FABRE MEDICAMENT
    Inventors: Frédéric MARION, Frédéric LIEBY-MULLER, Serge GRISONI, Emmannuel FOURNIER
  • Griseofulvin derivatives
    Patent number: 9416143
    Abstract: The present invention relates to compounds of the following general formula (I), or to a pharmaceutically acceptable salt thereof, as well as to the uses thereof as a drug, in particular in the treatment of cancerous or precancerous hyperproliferative conditions, and to the pharmaceutical compositions containing same.
    Type: Grant
    Filed: August 1, 2013
    Date of Patent: August 16, 2016
    Assignee: PIERRE FABRE MEDICAMENT
    Inventors: Frédéric Marion, Frédéric Lieby-Muller, Serge Grisoni, Nicolas Rahier, Michel Perez, Isabelle Sartori
  • Griseofulvin derivatives
    Patent number: 9416142
    Abstract: The present invention relates to compounds of the following general formula (I), or to a pharmaceutically acceptable salt thereof, as well as to the uses thereof as a drug, in particular for treating cancerous or precancerous hyperproliferative conditions, and to the pharmaceutical compositions containing same.
    Type: Grant
    Filed: August 1, 2013
    Date of Patent: August 16, 2016
    Assignee: PIERRE FABRE MEDICAMENT
    Inventors: Frédéric Marion, Frédéric Lieby-Muller, Serge Grisoni, Emmannuel Fournier
  • GRISEOFULVIN DERIVATIVES
    Publication number: 20150210713
    Abstract: The present invention relates to compounds of the following general formula (I), or to a pharmaceutically acceptable salt thereof, as well as to the uses thereof as a drug, in particular in the treatment of cancerous or precancerous hyperproliferative conditions, and to the pharmaceutical compositions containing same.
    Type: Application
    Filed: August 1, 2013
    Publication date: July 30, 2015
    Applicant: PIERRE FABRE MEDICAMENT
    Inventors: Frédéric Marion, Frédéric Lieby-Muller, Serge Grisoni, Nicolas Rahier, Michel Perez, Isabelle Sartori
  • GRISEOFULVIN DERIVATIVES
    Publication number: 20150191443
    Abstract: The present invention relates to compounds of the following general formula (I), or to a pharmaceutically acceptable salt thereof, as well as to the uses thereof as a drug, in particular for treating cancerous or precancerous hyperproliferative conditions, and to the pharmaceutical compositions containing same.
    Type: Application
    Filed: August 1, 2013
    Publication date: July 9, 2015
    Applicant: PIERRE FABRE MEDICAMENT
    Inventors: Frédéric Marion, Frédéric Lieby-Muller, Serge Grisoni, Emmannuel Fournier
  • Pyrroloquinoline derivatives and their use as protein kinases inhibitors
    Patent number: 8426437
    Abstract: The present invention relates to inhibitors of protein kinases of formula I: which can be used in the treatment of various diseases, notably cancer, inflammation or disorders of the central nervous system. It also relates to pharmaceutical compositions containing the compounds according to the invention and their use in therapy.
    Type: Grant
    Filed: June 30, 2006
    Date of Patent: April 23, 2013
    Assignee: Pierre Fabre Medicament
    Inventors: Hugues Bienayme, Antoine Dumoulin, Serge Grisoni, Bachir Kaloun El, Stephane Poigny, Remi Rabot, Rachid Rahali, Eric Tam, Pascaline Klein, Karim Bedjeguelal, Houcine Rahali
  • Pharmacological uses of azetidine derivatives
    Patent number: 7741316
    Abstract: A method of treating or preventing Alzheimer's disease, Parkinson's Disease and/or schizophrenia, this method comprising administering to a patient in need of such treatment a compound of formula: in which R, R3 and R4 are as defined in the specification.
    Type: Grant
    Filed: November 12, 2004
    Date of Patent: June 22, 2010
    Assignee: Aventis Pharma S.A.
    Inventors: Daniel Achard, Herve Bouchard, Jean Bouquerel, Bruno Filoche, Serge Grisoni, Augustin Hittinger, Michael R. Myers
  • Pyrroloquinoline Derivatives And Their Use As Protein Kinases Inhibitors
    Publication number: 20090042876
    Abstract: The present invention relates to inhibitors of protein kinases of formula I: which can be used in the treatment of various diseases, notably cancer, inflammation or disorders of the central nervous system. It also relates to pharmaceutical compositions containing the compounds according to the invention and their use in therapy.
    Type: Application
    Filed: June 30, 2006
    Publication date: February 12, 2009
    Applicant: Pierre Fabre Medicament
    Inventors: Hugues Bienayme, Antoine Dumoulin, Serge Grisoni, Bachir Kaloun El, Stephane Poigny, Remi Rabot, Rachid Rahali, Eric Tam, Pascaline Klein, Karim Bedjeguelal, Houcine Rahali
  • Streptogramin derivatives, their preparation and compositions containing them
    Patent number: 7166594
    Abstract: Group A streptogramin derivatives of general formula (I) in which: R1 represents a halogen atom or an azido or thiocyanato radical, R2 represents a hydrogen atom or a methyl or ethyl radical, R3 represents a hydrogen atom, or the residue of an aliphatic, cycloaliphatic, aromatic, araliphatic, heterocyclic or heterocyclylaliphatic ester which may be substituted, and the bond --- represents a single bond (stereochemistry 27R) or a double bond, as well as its salts when they exist
    Type: Grant
    Filed: December 6, 2002
    Date of Patent: January 23, 2007
    Assignee: Aventis Pharma S.A.
    Inventors: Daniel Achard, Eric Bacque, Jean-Claude Barriere, Jean Bouquerel, Pascal Desmazeau, Serge Grisoni, Jean-Pierre Leconte, Yves Ribeill, Baptiste Ronan
  • Pharmaceutical compositions containing 3-aminoazetidine derivatives, novel derivatives and their preparation
    Patent number: 7132414
    Abstract: The present invention relates to pharmaceutical compositions containing, as active ingredient, a compound of formula: in which R1 represents a radical —NHCOR4 or —N(R5)—Y—R6, Y is CO or SO2, R4 represents a radical -alk-SO2—R11, -alk-SO2—CH?CH—R11 or Het substituted with —SO2—R11 or a phenyl radical substituted with —SO2—R11 or -alk-SO2—R11, R5 represents a hydrogen atom or an alkyl radical, R6 represents a phenylalkyl, Het or Ar radical, to the novel derivatives of formula (I) and to their preparation, as well s to their use in treating various disorders of the nervous system.
    Type: Grant
    Filed: February 4, 2004
    Date of Patent: November 7, 2006
    Assignee: Aventis Pharma S.A.
    Inventors: Daniel Achard, Herve Bouchard, Jean Bouquerel, Bruno Filoche, Serge Grisoni, Augustin Hittinger, Michael R. Myers
  • Pharmacological uses of azetidine derivatives
    Publication number: 20050130953
    Abstract: A method of treating or preventing Alzheimer's disease, Parkinson's Disease and/or schizophrenia, this method comprising administering to a patient in need of such treatment a compound of formula: in which R, R3 and R4 are as defined in the specification.
    Type: Application
    Filed: November 12, 2004
    Publication date: June 16, 2005
    Applicant: Aventis Pharma S.A.
    Inventors: Daniel Achard, Herve Bouchard, Jean Bouquerel, Bruno Filoche, Serge Grisoni, Augustin Hittinger, Michael Myers
  • Pharmacological uses of azetidine derivatives
    Patent number: 6872717
    Abstract: A method of treating or preventing obesity, this method comprising administering to a patient in need of such treatment an effective amount of a compound of formula in which R, R3 and R4 are as defined in the specification.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: March 29, 2005
    Assignee: Aventis Pharma S.A.
    Inventors: Daniel Achard, Hervé Bouchard, Jean Bouquerel, Bruno Filoche, Serge Grisoni, Augustin Hittinger, Michael R. Myers
  • Pharmaceutical compositions containing 3-aminoazetidine derivatives, novel derivatives and their preparation
    Publication number: 20040157823
    Abstract: The present invention relates to pharmaceutical compositions containing, as active ingredient, a compound of formula: 1
    Type: Application
    Filed: February 4, 2004
    Publication date: August 12, 2004
    Applicant: Aventis Pharma S.A.
    Inventors: Daniel Achard, Herve Bouchard, Jean Bouquerel, Bruno Filoche, Serge Grisoni, Augustin Hittinger, Michael R. Myers
  • Pharmaceutical compositions containing 3-aminoazetidine derivatives, novel derivatives and their preparation
    Patent number: 6734176
    Abstract: The present invention relates to pharmaceutical compositions containing, as active ingredient, a compound of formula: in which R1 represents a radical —NHCOR4 or —N(R5)—Y—R6, Y is CO or SO2, R4 represents a radical -alk-SO2—R11, -alk-SO2—CH═CH—R11 or Het substituted with —SO2—R11 or a phenyl radical substituted with —SO2—R11 or -alk-SO2—R11, R5 represents a hydrogen atom or an alkyl radical, R6 represents a phenylalkyl, Het or Ar radical, to the novel derivatives of formula (I) and to their preparation, as well s to their use in treating various disorders of the nervous system.
    Type: Grant
    Filed: December 17, 2002
    Date of Patent: May 11, 2004
    Assignee: Aventis Pharma S.A.
    Inventors: Daniel Achard, Hervé Bouchard, Jean Bouquerel, Bruno Filoche, Serge Grisoni, Augustin Hittinger, Michael R. Myers
  • Streptogramin derivatives, their preparation and compositions containing them
    Publication number: 20030149004
    Abstract: Group A streptogramin derivatives of general formula (I) in which:
    Type: Application
    Filed: December 6, 2002
    Publication date: August 7, 2003
    Applicant: Aventis Pharma S.A.
    Inventors: Daniel Achard, Eric Bacque, Jean-Claude Barriere, Jean Bouquerel, Pascal Desmazeau, Serge Grisoni, Jean-Pierre Leconte, Yves Ribeill, Baptiste Ronan
  • Pharmaceutical compositions containing 3-aminoazetidine derivatives, novel derivatives and their preparation
    Publication number: 20030119810
    Abstract: The present invention relates to pharmaceutical compositions containing, as active ingredient, a compound of formula: 1
    Type: Application
    Filed: December 17, 2002
    Publication date: June 26, 2003
    Inventors: Daniel Achard, Herve Bouchard, Jean Bouquerel, Bruno Filoche, Serge Grisoni, Augustin Hittinger, Michael R. Myers
  • Streptogramin derivatives, their preparation and compositions containing them
    Patent number: 6569854
    Abstract: Group A streptogramin derivatives of general formula (I) in which: R1 represents a halogen atom or an azido or thiocyanato radical, R2 represents a hydrogen atom or a methyl or ethyl radical, R3 represents a hydrogen atom, or the residue of an aliphatic, cycloaliphatic, aromatic, araliphatic, heterocyclic or heterocyclylaliphatic ester which may be substituted, and the bond - - - represents a single bond (stereochemistry 27R) or a double bond, as well as its salts when they exist.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: May 27, 2003
    Assignee: Aventis Pharma S.A.
    Inventors: Daniel Achard, Eric Bacque, Jean-Claude Barriere, Jean Bouquerel, Pascal Desmazeau, Serge Grisoni, Jean-Pierre Leconte, Yves Ribeill, Baptiste Ronan