Patents by Inventor Serge Lavastre

Serge Lavastre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzene derivatives, their preparation and pharmaceutical compositions in which they are present
    Patent number: 5449693
    Abstract: The present invention relates to compounds of the formula ##STR1## in which: R.sub.1 is hydrogen or a halogen atom;R.sub.2 is a cyclohexyl or a phenyl;R.sub.3 is a (C.sub.3 -C.sub.6) cycloalkyl;R.sub.4 is hydrogen, (C.sub.1 -C.sub.6) alkyl or a (C.sub.3 -C.sub.6) cycloalkyl;A is --CO--CH.sub.2 --, --CH(Cl)--CH.sub.2 --, --CH(OH)--CH.sub.2 --, CH.sub.2 --CH.sub.2 --, --CH.dbd.CH-- and --C.tbd.C--, or their addition salts with mineral or organic acids. These compounds are active on the immune system. The present invention further relates to a method of preparing said compounds and to the pharmaceutical compounds in which they are present.
    Type: Grant
    Filed: June 22, 1994
    Date of Patent: September 12, 1995
    Assignee: Sanofi
    Inventors: Jean-Claude Breliere, Pierre Casellas, Serge Lavastre, Raymond Paul
  • Benzene derivatives, their preparation and pharmaceutical compositions in which they are present
    Patent number: 5354781
    Abstract: The present invention relates to compounds of the formula ##STR1## in which: p1 R.sub.1 is hydrogen or a halogen atom; R.sub.2 is a cyclohexyl or a phenyl;R.sub.3 is a (C.sub.3 -C.sub.6) cycloalkyl;R.sub.4 is hydrogen, (C.sub.1 -C.sub.6) alkyl or (C.sub.3 -C.sub.6)cycloalkyl;A is --CO--CH.sub.2 --, --CH(CI)--CH.sub.2 --, --CH(OH)--CH.sub.2 --, CH.sub.2 --CH.sub.2 --, --CH.dbd.CH-- and --C.tbd.C--, or their addition salt with mineral or organic acids. These compounds are active on the immune system. The present invention further relates to a method of preparing said compounds and to the pharmaceutical compounds in which they are present.
    Type: Grant
    Filed: May 24, 1991
    Date of Patent: October 11, 1994
    Assignee: Sanofi
    Inventors: Jean-Claude Breliere, Pierre Casellas, Serge Lavastre, Raymond Paul
  • Hexahydroazepine derivatives, a process for their preparation
    Patent number: 5296596
    Abstract: The present invention relates to hexahydroazepine derivatives of formula ##STR1## in which: A=--CO--CH.sub.2 --, --CH(OH)--CH.sub.2 --; --CH.sub.2 --CH.sub.2 --; --CH.dbd.CH--; --C.tbd.C--;X=H or a halogen;Y=cyclohexyl or, when X is H, phenyl.It likewise relates to the salts of the said derivatives, to a process for the preparation of these and to the pharmaceutical compositions containing them, more particularly as antipsychotic agents.
    Type: Grant
    Filed: April 14, 1993
    Date of Patent: March 22, 1994
    Assignee: ELF SANOFI
    Inventors: Serge Lavastre, Jean-Pierre Maignan, Raymond Paul, Martine Poncelet, Vincent Santucci
  • Hexahydroazepine derivatives and pharmaceutical compositions containing them
    Patent number: 5231092
    Abstract: The present invention relates to hexahydroazepine derivatives of formula ##STR1## in which: A=--CO--CH.sub.2 --, --CH(OH--CH.sub.2 --; --CH.sub.2 --CH.sub.2 --CH.sub.2 --;--CH.dbd.CH--; --C.tbd.C--;X=H or a halogen;Y=cylcohexyl or, when X is H, phenyl.It likewise relates to the salts of the said derivatives, to a process for the preparation of these and to the pharmaceutical compositions containing them, more particularly as antipsychotic agents.
    Type: Grant
    Filed: June 13, 1991
    Date of Patent: July 27, 1993
    Assignee: Sanofi
    Inventors: Serge Lavastre, Jean-Pierre Maignan, Raymond Paul, Martine Poncelet, Vincent Santucci