Patents by Inventor Serge Maria Aloysius Pieters

Serge Maria Aloysius Pieters has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FUSED RING PYRIMIDONE DERIVATIVES FOR USE IN THE TREATMENT OF HBV INFECTION OR OF HBV-INDUCED DISEASES
    Publication number: 20230091047
    Abstract: The present application relates to compounds according to Formula (I), pharmaceutical compositions comprising at least one of said compounds, their use as a medicament, and their use in treating chronic hepatitis B virus (HBV) infection. The disclosure further pertains to methods for preparing compounds according to Formula (I).
    Type: Application
    Filed: March 13, 2020
    Publication date: March 23, 2023
    Inventors: Sandrine Céline GROSSE, Jan Martin BERKE, Meng-yang HSIAO, Lili HU, Edgar JACOBY, Tim Hugo Maria JONCKERS, Bart Rudolf Romanie KESTELEYN, Stefaan Julien LAST, Carlolina MARTINEZ LAMENCA, Mathieu PERRIER, Serge Maria Aloysius PIETERS, Pierre Jean-Marie Bernard RABOISSON, Abdellah TAHRI, Koen VANDYCK, Wim Gaston VERSCHUEREN
  • Pyrimidine derivatives for the treatment of viral infections
    Patent number: 11541050
    Abstract: This invention relates to pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections such as HCV or HBV.
    Type: Grant
    Filed: September 4, 2020
    Date of Patent: January 3, 2023
    Assignee: JANSSEN SCIENCES IRELAND UC
    Inventors: David Mc Gowan, Pierre Jean-Marie Bernard Raboisson, Werner Embrechts, Tim Hugo Maria Jonckers, Stefaan Julien Last, Serge Maria Aloysius Pieters, Jaromir Vlach
  • FUSED HETEROCYCLIC DERIVATIVES
    Publication number: 20220348592
    Abstract: The application describes fused heterocycle derivative compounds, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment of diseases associated with HBV infection.
    Type: Application
    Filed: May 27, 2020
    Publication date: November 3, 2022
    Inventors: Sandrine Celine GROSSE, Scott D. KUDUK, Lindsey Graham DERATT, Koen VANDYCK, Pierre Jean-Marien Bernard RABOISSON, Serge Maria Aloysius PIETERS, Bart Rudolf Romanie KESTELEYN, Wim Gaston VERSCHUEREN, Jan Martin BERKE, Morgan Charles R. LECOMTE, Carolina MARTINEZ LAMENCA, Tim Hugo Maria JONCKERS, Gang DENG, Yimin JIANG, Yanping XU, Zhangling CHENG, Lili HU
  • Pyrrolo[3,2-d] pyrimidine derivatives for the treatment of viral infections and other diseases
    Patent number: 11220504
    Abstract: This invention concerns pyrrolo[3,2-d]pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treatment and/or therapy of diseases.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: January 11, 2022
    Assignee: JANSSEN SCIENCES IRELAND UNLIMITED COMPANY
    Inventors: David Craig McGowan, Stefaan Julien Last, Serge Maria Aloysius Pieters, Werner Embrechts, Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson
  • CYCLIZED SULFAMOYLARYLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B
    Publication number: 20210179635
    Abstract: Inhibitors of HBV replication of Formula (I-A) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein Ra to Rd, and R1 to R8 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.
    Type: Application
    Filed: December 18, 2020
    Publication date: June 17, 2021
    Inventors: Sandrine Marie Helene VENDEVILLE, Stefaan Julien LAST, Samuël Dominique DEMIN, Sandrine Céline GROSSE, Geerwin Yvonne Paul HACHÉ, Lili HU, Serge Maria Aloysius PIETERS, Geert ROMBOUTS, Koen VANDYCK, Wim Gaston VERSCHUEREN, Pierre Jean-Marie Bernard RABOISSON
  • PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS
    Publication number: 20210023082
    Abstract: This invention relates to pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections such as HCV or HBV.
    Type: Application
    Filed: September 4, 2020
    Publication date: January 28, 2021
    Inventors: David McGowan, Pierre Jean-Marie Bernard Raboisson, Werner Embrachts, Tim Hugo Maria Jonckers, Stefaan Julien Last, Serge Maria Aloysius Pieters, Jeromir Vlach
  • Cyclized sulfamoylarylamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
    Patent number: 10875876
    Abstract: Inhibitors of HBV replication of Formula (I-A) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein Ra to Rd, and R1 to R8 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: December 29, 2020
    Assignee: JANSSEN SCIENCES IRELAND UC
    Inventors: Sandrine Marie Helene Vendeville, Stefaan Julien Last, Samuël Dominique Demin, Sandrine Céline Grosse, Geerwin Yvonne Paul Haché, Lili Hu, Serge Maria Aloysius Pieters, Geert Rombouts, Koen Vandyck, Wim Gaston Verschueren, Pierre Jean-Marie Bernard Raboisson
  • Pyrrolo [3,2-d]pyrimidine derivatives for the treatment of viral infections and other diseases
    Patent number: 10781216
    Abstract: This invention concerns pyrrolo[3,2-d]pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treatment and/or therapy of diseases.
    Type: Grant
    Filed: June 14, 2019
    Date of Patent: September 22, 2020
    Assignee: JANSSEN SCIENCES IRELAND UNLIMITED COMPANY
    Inventors: David Craig McGowan, Serge Maria Aloysius Pieters, Stefaan Julien Last, Werner Embrechts, Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson
  • Pyrimidine derivatives for the treatment of viral infections
    Patent number: 10780089
    Abstract: This invention relates to pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections such as HCV or HBV.
    Type: Grant
    Filed: August 2, 2019
    Date of Patent: September 22, 2020
    Assignee: JANSSEN SCIENCES IRELAND UC
    Inventors: David McGowan, Pierre Jean-Marie Bernard Raboisson, Werner Embrechts, Tim Hugo Maria Jonckers, Stefaan Julien Last, Serge Maria Aloysius Pieters, Jaromir Vlach
  • Heterocyclic substituted 2-amino quinazoline derivatives for the treatment of viral infections
    Patent number: 10723707
    Abstract: This invention relates to heterocyclic substituted 2-amino-quinazoline derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: July 28, 2020
    Assignee: Janssen Sciences Ireland Unlimited Company
    Inventors: Stefaan Julien Last, David Craig McGowan, Werner Embrechts, Serge Maria Aloysius Pieters, Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson
  • PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS
    Publication number: 20200061059
    Abstract: This invention relates to pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections such as HCV or HBV.
    Type: Application
    Filed: August 2, 2019
    Publication date: February 27, 2020
    Inventors: David McGowan, Pierre Jean-Marie Bernard Raboisson, Werner Embrechts, Tim Hugo Maria Jonckers, Stefaan Julien Last, Serge Maria Aloysius Pieters, Jaromir Vlach
  • PYRROLO[3,2-D]PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND OTHER DISEASES
    Publication number: 20200002342
    Abstract: This invention concerns pyrrolo[3,2-d]pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treatment and/or therapy of diseases.
    Type: Application
    Filed: June 14, 2019
    Publication date: January 2, 2020
    Inventors: David Craig MC GOWAN, Serge Maria Aloysius PIETERS, Stefaan Julien LAST, Werner EMBRECHTS, Tim Hugo Maria JONCKERS, Pierre Jean-Marie Bernard RABOISSON
  • PYRROLO[3,2-D]PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND OTHER DISEASES
    Publication number: 20190330217
    Abstract: This invention concerns pyrrolo[3,2-d]pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treatment and/or therapy of diseases.
    Type: Application
    Filed: April 12, 2019
    Publication date: October 31, 2019
    Inventors: David Craig MC GOWAN, Stefaan Julien LAST, Serge Maria Aloysius PIETERS, Werner EMBRECHTS, Tim Hugo Maria JONCKERS, Pierre Jean-Marie Bernard RABOISSON
  • HETEROCYCLIC SUBSTITUTED 2-AMINO QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS
    Publication number: 20190330160
    Abstract: This invention relates to heterocyclic substituted 2-amino-quinazoline derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Application
    Filed: April 8, 2019
    Publication date: October 31, 2019
    Inventors: Stefaan Julien Last, David Craig Mc Gowan, Werner Embrechts, Serge Maria Aloysius Pieters, Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson
  • Glyoxamide substituted pyrrolamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
    Patent number: 10450270
    Abstract: Inhibitors of HBV replication of Formula (IA) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein X and R1 to R6 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.
    Type: Grant
    Filed: July 25, 2014
    Date of Patent: October 22, 2019
    Assignee: Janssen Sciences Ireland UC
    Inventors: Koen VanDyck, Bart Rudolf Romanie Kesteleyn, Serge Maria Aloysius Pieters, Geert Rombouts, Wim Gaston Verschueren, Pierre Jean-Marie Bernard Raboisson
  • Pyrimidine derivatives for the treatment of viral infections
    Patent number: 10420767
    Abstract: This invention relates to pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections such as HCV or HBV.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: September 24, 2019
    Assignee: Janssen Sciences Ireland UC
    Inventors: David McGowan, Pierre Jean-Marie Bernard Raboisson, Werner Embrechts, Tim Hugo Maria Jonckers, Stefaan Julien Last, Serge Maria Aloysius Pieters, Jaromir Vlach
  • Pyrrolo[3,2-d]pyrimidine derivatives for the treatment of viral infections and other diseases
    Patent number: 10385054
    Abstract: This invention concerns pyrrolo[3,2-d]pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treatment and/or therapy of diseases.
    Type: Grant
    Filed: June 26, 2014
    Date of Patent: August 20, 2019
    Assignee: Janssen Sciences Ireland Unlimited Company
    Inventors: David Craig McGowan, Serge Maria Aloysius Pieters, Stefaan Julien Last, Werner Embrechts, Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson
  • Pyrimidine derivatives for the treatment of viral infections
    Patent number: 10272085
    Abstract: This invention relates to pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections such as HCV or HBV.
    Type: Grant
    Filed: July 13, 2016
    Date of Patent: April 30, 2019
    Assignee: Janssen Sciences Ireland UC
    Inventors: David McGowan, Pierre Jean-Marie Bernard Raboisson, Werner Embrechts, Tim Hugo Maria Jonckers, Stefaan Julien Last, Serge Maria Aloysius Pieters, Jaromir Vlach
  • Pyrrolo[3,2-d]pyrimidine derivatives for the treatment of viral infections and other diseases
    Patent number: 10259814
    Abstract: This invention concerns pyrrolo[3,2-d]pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treatment and/or therapy of diseases.
    Type: Grant
    Filed: October 25, 2016
    Date of Patent: April 16, 2019
    Assignee: Janssen Sciences Ireland UC
    Inventors: David Craig McGowan, Stefaan Julien Last, Serge Maria Aloysius Pieters, Werner Embrechts, Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson
  • Heterocyclic substituted 2-amino quinazoline derivatives for the treatment of viral infections
    Patent number: 10253003
    Abstract: This invention relates to heterocyclic substituted 2-amino-quinazoline derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Grant
    Filed: May 10, 2017
    Date of Patent: April 9, 2019
    Assignee: Janssen Sciences Ireland UC
    Inventors: Stefaan Julien Last, David Craig McGowan, Werner Embrechts, Serge Maria Aloysius Pieters, Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson