Patents by Inventor Serge Timsit

Serge Timsit has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BLOOD BIOMARKERS OF STROKE
    Publication number: 20210214793
    Abstract: Stroke is a devastating disorder that significantly contributes to death, disability and health care costs. The current challenge is to prevent late cell death, with concomitant therapy to widen the therapeutic window. A potential diagnostic method for stroke is the use of RNA in the blood as a biomarker, which is an emerging field in medicine. Here the inventors explore the expression of genes after the onset of cerebral ischemia in the brain and blood. The study of macaque microarray expression data from brain and blood revealed that ischemic and nonischaemic samples can be distinguished based on their expression profiles, and the majority of highly differentially expressed genes are up-regulated in the ischemic scenario 6 hours after ischemia. A comparison of differentially expressed genes in the brain and the blood revealed a significant overlap of gene expression patterns.
    Type: Application
    Filed: May 16, 2019
    Publication date: July 15, 2021
    Inventors: Serge TIMSIT, Emmanuelle GENIN
  • Administration of (S)-roscovitine for protection against and/or treatment of neurological diseases
    Patent number: 8318707
    Abstract: The present invention relates to the use of 6-(benzyl-amino)-2(S)-[[1-(hydroxymethyl) propyl]amino]-9-isopropylpurine) or at least one of its pharmaceutical acceptable salts for manufacturing a medication intended for the prevention and/or treatment of neurological diseases, in particular associated with neurological lesions.
    Type: Grant
    Filed: March 30, 2007
    Date of Patent: November 27, 2012
    Assignee: Neurokin
    Inventors: Serge Timsit, Bénédicte Menn, Laurent Meijer
  • Use of (S)-Roscovitine for Prevention and/or Treatment of Neurological Diseases
    Publication number: 20100008927
    Abstract: The present invention relates to the use of 6-(benzyl-amino)-2(S)-[[1-(hydroxymethyl) propyl]amino]-9-isopropylpurine) or at least one of its pharmaceutical acceptable salts for manufacturing a medication intended for the prevention and/or treatment of neurological diseases, in particular associated with neurological lesions.
    Type: Application
    Filed: March 30, 2007
    Publication date: January 14, 2010
    Applicant: NEUROKIN INMED
    Inventors: Serge Timsit, Bénédicte Menn, Laurent Meijer
  • Method of treating and preventing acute neural lesions with substances that modulate the expression or function of a protein involved in the cell cycle and pharmaceutical preparations containing such substances
    Publication number: 20030060397
    Abstract: A method of treating or preventing non-apoptotic excitotoxic acute neural lesions in a patient including administering a therapeutically effective amount of a substance that modulates expression or the function of a protein involved in cell cycles, and a pharmaceutical preparation for treating or preventing non-apoptotic excitotoxic acute neural lesions including a therapeutically effective amount of a substance that modulates expression or the function of a protein involved in the cell cycle.
    Type: Application
    Filed: September 20, 2002
    Publication date: March 27, 2003
    Applicant: Centre National de la Recherche Scientifique - CNRS and Inserm
    Inventors: Serge Timsit, Pauline Cavelier, Yehezkel Ben-Ari, Michel Khrestchatisky, Laurent Meijer