Patents by Inventor Sergei Atamas

Sergei Atamas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic targeting of PARC/CCL18 and its signaling in pulmonary fibrosis
    Publication number: 20060009452
    Abstract: The present invention relates to methods of treating, preventing or preventing the progression of fibrosis comprising inhibiting the actions of pulmonary and activation-regulated chemokine (PARC) or at least one of its downstream effector molecules, such as Sp1 transcription factor and protein kinase C-alpha (PKC?). The present invention also relates to methods of screening and/or identifying compounds useful for the treatment of fibrosis comprising contacting PARC or its downstream effector molecules, such as Sp1 or PKC?, with a substance and subsequently determining the effects of the substance on the activity of PARC or Sp1 or PKC?. The present invention also relates to methods of screening and/or identifying compounds that prevent or inhibit collagen deposition comprising contacting PARC or its downstream effector molecules, such as Sp1 or PKC?, with a substance and subsequently determining the effects of the substance on the activity of PARC or Sp1 or PKC?.
    Type: Application
    Filed: June 3, 2005
    Publication date: January 12, 2006
    Inventors: Sergei Atamas, Irina Luzina, Barbara White