Patents by Inventor Sergei Danilov

Sergei Danilov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SINGLE CHAIN FRAGMENT OF MONOCLONAL ANTIBODY 9B9 AND USES THEREOF
    Publication number: 20120213699
    Abstract: Anti-ACE single chain fragment antibodies are disclosed. The present invention relates to using these antibodies, and polymers thereof, in methods for detecting, diagnosing, prognosing, preventing, or treating diseases associated with ACE expressing tissue.
    Type: Application
    Filed: May 3, 2012
    Publication date: August 23, 2012
    Applicant: The Board of Trustees of the University of Illinois
    Inventors: Irina Balyasnikova, Sergei Danilov
  • Anti-rat angiotensin I-converting enzyme (ACE, CD143) monoclonal antibodies and uses thereof
    Publication number: 20050287066
    Abstract: It was demonstrated previously that mAb 9B9 to ACE accumulated selectively in the rat lung after systemic injection and thus could be used as a powerful tool for immunotargeting therapeutic agents/genes to the lung microvasculature. The current invention generated novel set of monoclonal antibodies (mAbs) to rat ACE in order to enhance the repertoire of mAbs suitable for targeting drugs/genes to the rat lung. Provided are methods used to characterize the ability of these mAbs to target ACE in vitro and to the lung endothelium in vivo. The anti-rat ACE mAbs of the present invention demonstrated highly efficient and selective accumulation in the lung.
    Type: Application
    Filed: June 28, 2005
    Publication date: December 29, 2005
    Inventors: Sergei Danilov, Irina Balyasnikova