Patents by Inventor Sergei Doulatov

Sergei Doulatov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and methods for treatment of Diamond Blackfan anemia
    Patent number: 11980620
    Abstract: The present invention relates generally to methods for treatment of ribosomal disorders and ribosomopathy, e.g. Diamond Blackfan anemia (DBA). In some embodiments, the invention relates to methods for the use of a small-molecule autophagy modulator for treatment of ribosomal disorders and ribosomopathy. The invention also relates to small molecule drug discovery and methods of screening compositions to determine their effectiveness for treatment of ribosomal disorders and ribosomopathies.
    Type: Grant
    Filed: June 8, 2017
    Date of Patent: May 14, 2024
    Assignee: THE CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Sergei Doulatov, George Q. Daley
  • COMPOUNDS AND METHODS FOR TREATMENT OF DIAMOND BLACKFAN ANEMIA
    Publication number: 20200188402
    Abstract: The present invention relates generally to methods for treatment of ribosomal disorders and ribosomopathy, e.g. Diamond Blackfan anemia (DBA). In some embodiments, the invention relates to methods for the use of a small-molecule autophagy modulator for treatment of ribosomal disorders and ribosomopathy. The invention also relates to small molecule drug discovery and methods of screening compositions to determine their effectiveness for treatment of ribosomal disorders and ribosomopathies.
    Type: Application
    Filed: June 8, 2017
    Publication date: June 18, 2020
    Applicant: THE CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Sergei DOULATOV, George Q. DALEY
  • Self-Renewing Single Human Hematopoietic Stem Cells, an Early Lymphoid Progenitor and Methods of Enriching the Same
    Publication number: 20120252060
    Abstract: This invention relates to human hematopoietic stem cells. Specifically the invention relations to the identification of single human hematopoietic stem cells capable of long-term multilineage engraftment and self-renewal. The invention also relates to an early lymphoid progenitor with monocytic potential, including dendritic cell potential.
    Type: Application
    Filed: October 8, 2010
    Publication date: October 4, 2012
    Inventors: John Dick, Faiyaz Notta, Sergei Doulatov, Elisa Laurenti
  • SITE SPECIFIC SYSTEM FOR GENERATING DIVERSITY PROTEIN SEQUENCES
    Publication number: 20100041033
    Abstract: This invention relates to the diversification of nucleic acid sequences by use of a nucleic acid molecule containing a region of sequence that acts as a template for diversification. The invention thus provides nucleic acid molecules to be diversified, as well as those which act as the template region (TR) and in concert with the TR for directional, site-specific diversification. Further provided are methods of preparing and using these nucleic acid sequences.
    Type: Application
    Filed: February 10, 2009
    Publication date: February 18, 2010
    Applicants: The Regents of the University of California, AvidBiotics Corp.
    Inventors: Jeffery F. Miller, Sergei Doulatov, Asher Hodes, Min Rennella, Mari Gingery, Huatao Guo, David W. Martin
  • Site specific system for generating diversity protein sequences
    Patent number: 7585957
    Abstract: This invention relates to the diversification of nucleic acid sequences by use of a nucleic acid molecule containing a region of sequence that acts as a template for diversification. The invention thus provides nucleic acid molecules to be diversified, as well as those which act as the template region (TR) and in concert with the TR for directional, site-specific diversification. Further provided are methods of preparing and using these nucleic acid sequences.
    Type: Grant
    Filed: August 3, 2005
    Date of Patent: September 8, 2009
    Assignees: The Regents of the University of California, AvidBiotics Corp
    Inventors: Jeffery F. Miller, Sergei Doulatov, Asher Hodes, Min Xu, Mari Gingery, David W. Martin, Jr.
  • Site specific system for generating diversity protein sequences
    Publication number: 20060121450
    Abstract: This invention relates to the diversification of nucleic acid sequences by use of a nucleic acid molecule containing a region of sequence that acts as a template for diversification. The invention thus provides nucleic acid molecules to be diversified, as well as those which act as the template region (TR) and in concert with the TR for directional, site-specific diversification. Further provided are methods of preparing and using these nucleic acid sequences.
    Type: Application
    Filed: August 3, 2005
    Publication date: June 8, 2006
    Applicants: The Regents of the University of California, AvidBiotics Corporation
    Inventors: Jeffery Miller, Sergei Doulatov, Asher Hodes, Min Xu, Mari Gingery, David Martin