Patents by Inventor Sergei Skarupo
Sergei Skarupo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11965883Abstract: Provided are point of care sensor systems that include portable readers and disposable cartridges for receiving and analyzing samples. A cartridge may be equipped with one or more sensor channels, each containing one or more sensors. After providing a sample to a cartridge, the cartridge can be inserted into a reader, which can interact with the cartridge to perform on-cartridge sensing and receive signals indicating the presence and/or quantity of one or more targets in the sample. Examples of cartridges can include cardiac panels, sepsis panels and the like. In some embodiments, the same sensor hardware may be configured for multiple measurements of different targets conducted at different time frames. Also provided herein are novel on-cartridge solid and liquid reagent storage and delivery mechanisms.Type: GrantFiled: November 7, 2019Date of Patent: April 23, 2024Assignee: Nanomix, Inc.Inventors: Bradley N. Johnson, Jui-Ming Yang, Kanchan A. Joshi, Ray R. Radtkey, Garrett Gruener, Sergei Skarupo
-
Publication number: 20200232981Abstract: Provided are point of care sensor systems that include portable readers and disposable cartridges for receiving and analyzing samples. A cartridge may be equipped with one or more sensor channels, each containing one or more sensors. After providing a sample to a cartridge, the cartridge can be inserted into a reader, which can interact with the cartridge to perform on-cartridge sensing and receive signals indicating the presence and/or quantity of one or more targets in the sample. Examples of cartridges can include cardiac panels, sepsis panels and the like. In some embodiments, the same sensor hardware may be configured for multiple measurements of different targets conducted at different time frames. Also provided herein are novel on-cartridge solid and liquid reagent storage and delivery mechanisms.Type: ApplicationFiled: November 7, 2019Publication date: July 23, 2020Applicant: Nanomix, Inc.Inventors: Bradley N. Johnson, Jui-Ming Yang, Kanchan A. Joshi, Ray R. Radtkey, Garrett Gruener, Sergei Skarupo
-
Patent number: 10520501Abstract: Provided are point of care sensor systems that include portable readers and disposable cartridges for receiving and analyzing samples. A cartridge may be equipped with one or more sensor channels, each containing one or more sensors. After providing a sample to a cartridge, the cartridge can be inserted into a reader, which can interact with the cartridge to perform on-cartridge sensing and receive signals indicating the presence and/or quantity of one or more targets in the sample. Examples of cartridges can include cardiac panels, sepsis panels and the like. In some embodiments, the same sensor hardware may be configured for multiple measurements of different targets conducted at different time frames. Also provided herein are novel on-cartridge solid and liquid reagent storage and delivery mechanisms.Type: GrantFiled: September 9, 2016Date of Patent: December 31, 2019Assignee: Nanomix, Inc.Inventors: Bradley N. Johnson, Jui-Ming Yang, Kanchan A. Joshi, Ray R. Radtkey, Garrett Gruener, Sergei Skarupo
-
Publication number: 20170153230Abstract: Provided are point of care sensor systems that include portable readers and disposable cartridges for receiving and analyzing samples. A cartridge may be equipped with one or more sensor channels, each containing one or more sensors. After providing a sample to a cartridge, the cartridge can be inserted into a reader, which can interact with the cartridge to perform on-cartridge sensing and receive signals indicating the presence and/or quantity of one or more targets in the sample. Examples of cartridges can include cardiac panels, sepsis panels and the like. In some embodiments, the same sensor hardware may be configured for multiple measurements of different targets conducted at different time frames. Also provided herein are novel on-cartridge solid and liquid reagent storage and delivery mechanisms.Type: ApplicationFiled: September 9, 2016Publication date: June 1, 2017Inventors: Bradley N. Johnson, Jui-Ming Yang, Kanchan A. Joshi, Ray R. Radtkey, Garrett Gruener, Sergei Skarupo
-
Patent number: 9458488Abstract: Provided are point of care sensor systems that include portable readers and disposable cartridges for receiving and analyzing samples. A cartridge may be equipped with one or more sensor channels, each containing one or more sensors. After providing a sample to a cartridge, the cartridge can be inserted into a reader, which can interact with the cartridge to perform on-cartridge sensing and receive signals indicating the presence and/or quantity of one or more targets in the sample. Examples of cartridges can include cardiac panels, sepsis panels and the like. In some embodiments, the same sensor hardware may be configured for multiple measurements of different targets conducted at different time frames. Also provided herein are novel on-cartridge solid and liquid reagent storage and delivery mechanisms.Type: GrantFiled: March 15, 2013Date of Patent: October 4, 2016Assignee: Nanomix, Inc.Inventors: Bradley N. Johnson, Jui-Ming Yang, Kanchan A. Joshi, Ray R. Radtkey, Garrett Gruener, Sergei Skarupo
-
Publication number: 20160123947Abstract: Embodiments of nanoelectronic sensors are described, including sensors for detecting analytes such ammonia. An environmental control system employing nanoelectronic sensors is described. A personnel safety system configured as a disposable badge employing nanoelectronic sensors is described. A method of dynamic sampling and exposure of a sensor providing a number of operational advantages is described.Type: ApplicationFiled: May 28, 2015Publication date: May 5, 2016Inventors: Mikhail Briman, Craig Bryant, Ying-Lan Chang, Jean-Christophe P. Gabriel, Shripal C. Ghandi, Bradley N. Johnson, Willem-Jan Ouborg, John Loren Passmore, Kastooriranganathan Ramakrishnan, Sergei Skarupo, Alexander Star, Christian Valcke
-
Patent number: 9291613Abstract: Sensors and detection systems suitable for measuring analytes, such as biomolecule, organic and inorganic species, including environmentally and medically relevant volatiles and gases, such as NO, NO2, CO2, NH3, H2, CO and the like, are provided. Certain embodiments of nanostructured sensor systems are configured for measurement of medically important gases in breath. Applications include the measurement of endogenous nitric oxide (NO) in breath, such as for the monitoring or diagnosis of asthma and other pulmonary conditions.Type: GrantFiled: June 16, 2014Date of Patent: March 22, 2016Assignee: Nanomix, Inc.Inventors: Craig Bryant, Ying-Lan Chang, Jean-Christophe P. Gabriel, Bradley N. Johnson, Oleksandr Kuzmych, William Mickelson, John Loren Passmore, Sergei Skarupo, Christian Valcke
-
Patent number: 9103775Abstract: Embodiments of nanoelectronic sensors are described, including sensors for detecting analytes inorganic gases, organic vapors, biomolecules, viruses and the like. A number of embodiments of capacitive sensors having alternative architectures are described. Particular examples include integrated cell membranes and membrane-like structures in nanoelectronic sensors.Type: GrantFiled: April 10, 2012Date of Patent: August 11, 2015Assignee: Nanomix, Inc.Inventors: Keith Bradley, Ying-Lan Chang, Jean-Christophe P. Gabriel, John Loren Passmore, Sergei Skarupo, Eugene Tu, Christian Valcke
-
Publication number: 20150008486Abstract: Sensors and detection systems suitable for measuring analytes, such as biomolecule, organic and inorganic species, including environmentally and medically relevant volatiles and gases, such as NO, NO2, CO2, NH3, H2, CO and the like, are provided. Certain embodiments of nanostructured sensor systems are configured for measurement of medically important gases in breath. Applications include the measurement of endogenous nitric oxide (NO) in breath, such as for the monitoring or diagnosis of asthma and other pulmonary conditions.Type: ApplicationFiled: June 16, 2014Publication date: January 8, 2015Inventors: Craig Bryant, Ying-Lan Chang, Jean-Christophe P. Gabriel, Bradley N. Johnson, Oleksandr Kuzmych, William Mickelson, John Loren Passmore, Sergei Skarupo, Christian Valcke
-
Publication number: 20140273187Abstract: Provided are point of care sensor systems that include portable readers and disposable cartridges for receiving and analyzing samples. A cartridge may be equipped with one or more sensor channels, each containing one or more sensors. After providing a sample to a cartridge, the cartridge can be inserted into a reader, which can interact with the cartridge to perform on-cartridge sensing and receive signals indicating the presence and/or quantity of one or more targets in the sample. Examples of cartridges can include cardiac panels, sepsis panels and the like. In some embodiments, the same sensor hardware may be configured for multiple measurements of different targets conducted at different time frames. Also provided herein are novel on-cartridge solid and liquid reagent storage and delivery mechanisms.Type: ApplicationFiled: March 15, 2013Publication date: September 18, 2014Inventors: Bradley N. Johnson, Jui-Ming Yang, Kanchan A. Joshi, Ray R. Radtkey, Garrett Gruener, Sergei Skarupo
-
Patent number: 8754454Abstract: Sensors and detection systems suitable for measuring analytes, such as biomolecule, organic and inorganic species, including environmentally and medically relevant volatiles and gases, such as NO, NO2, CO2, NH3, H2, CO and the like, are provided. Certain embodiments of nanostructured sensor systems are configured for measurement of medically important gases in breath. Applications include the measurement of endogenous nitric oxide (NO) in breath, such as for the monitoring or diagnosis of asthma and other pulmonary conditions.Type: GrantFiled: April 11, 2011Date of Patent: June 17, 2014Assignee: Nanomix, Inc.Inventors: Craig Bryant, Ying-Lan Chang, Jean-Christophe P. Gabriel, Bradley N. Johnson, Oleksandr Kuzmych, William Mickelson, John Loren Passmore, Sergei Skarupo, Christian Valcke
-
Publication number: 20130075690Abstract: Embodiments of nanoelectronic sensors are described, including sensors for detecting analytes such ammonia. An environmental control system employing nanoelectronic sensors is described. A personnel safety system configured as a disposable badge employing nanoelectronic sensors is described. A method of dynamic sampling and exposure of a sensor providing a number of operational advantages is described.Type: ApplicationFiled: April 9, 2012Publication date: March 28, 2013Applicant: NANOMIX, INC.Inventors: Mikhail Briman, Craig Bryant, Ying-Lan Chang, Jean-Christophe P. Gabriel, Shripal C. Gandhi, Bradley N. Johnson, Willem-Jan Ouborg, John Loren Passmore, Kastooriranganathan Ramakrishnan, Sergei Skarupo, Alexander Star, Christian Valcke
-
Publication number: 20130075794Abstract: Embodiments of nanoelectronic sensors are described, including sensors for detecting analytes inorganic gases, organic vapors, biomolecules, viruses and the like. A number of embodiments of capacitive sensors having alternative architectures are described. Particular examples include integrated cell membranes and membrane-like structures in nanoelectronic sensors.Type: ApplicationFiled: April 10, 2012Publication date: March 28, 2013Inventors: Keith Bradley, Ying-Lan Chang, Jean-Christophe P. Gabriel, John Loren Passmore, Sergei Skarupo, Eugene Tu, Christian Valcke
-
Patent number: 8154093Abstract: Embodiments of nanoelectronic sensors are described, including sensors for detecting analytes inorganic gases, organic vapors, biomolecules, viruses and the like. A number of embodiments of capacitive sensors having alternative architectures are described. Particular examples include integrated cell membranes and membrane-like structures in nanoelectronic sensors.Type: GrantFiled: April 6, 2006Date of Patent: April 10, 2012Assignee: Nanomix, Inc.Inventors: Keith Bradley, Ying-Lan Chang, Jean-Christophe P. Gabriel, John Loren Passmore, Sergei Skarupo, Eugene Tu, Christian Valcke
-
Patent number: 8152991Abstract: Embodiments of nanoelectronic sensors are described, including sensors for detecting analytes such ammonia. An environmental control system employing nanoelectronic sensors is described. A personnel safety system configured as a disposable badge employing nanoelectronic sensors is described. A method of dynamic sampling and exposure of a sensor providing a number of operational advantages is described.Type: GrantFiled: December 8, 2006Date of Patent: April 10, 2012Assignee: Nanomix, Inc.Inventors: Mikhail Briman, Craig Bryant, Ying-Lan Chang, Jean-Christophe P. Gabriel, Shirpal C. Gandhi, Bradley N Johnson, Willem-Jan Ouborg, John Loren Passmore, Kastooriranganathan Ramakrishnan, Sergei Skarupo, Alexander Star, Christian Valcke
-
Publication number: 20120006102Abstract: Sensors and detection systems suitable for measuring analytes, such as biomolecule, organic and inorganic species, including environmentally and medically relevant volatiles and gases, such as NO, NO2, CO2, NH3, H2, CO and the like, are provided. Certain embodiments of nanostructured sensor systems are configured for measurement of medically important gases in breath. Applications include the measurement of endogenous nitric oxide (NO) in breath, such as for the monitoring or diagnosis of asthma and other pulmonary conditions.Type: ApplicationFiled: April 11, 2011Publication date: January 12, 2012Applicant: NANOMIX, INC.Inventors: Craig Bryant, Ying-Lan Chang, Jean-Christophe P. Gabriel, Bradley N. Johnson, Oleksandr Kuzmych, William Mickelson, John Loren Passmore, Sergei Skarupo, Christian Valcke
-
Patent number: 7948041Abstract: Sensors and detection systems suitable for measuring analytes, such as biomolecule, organic and inorganic species, including environmentally and medically relevant volatiles and gases, such as NO, NO2, CO2, NH3, H2, CO and the like, are provided. Certain embodiments of nanostructured sensor systems are configured for measurement of medically important gases in breath. Applications include the measurement of endogenous nitric oxide (NO) in breath, such as for the monitoring or diagnosis of asthma and other pulmonary conditions.Type: GrantFiled: October 25, 2007Date of Patent: May 24, 2011Assignee: Nanomix, Inc.Inventors: Craig Bryant, Ying-Lan Chang, Jean-Christophe P. Gabriel, Bradley N. Johnson, Oleksandr Kuzmych, William Mickelson, John Loren Passmore, Sergei Skarupo, Christian Valcke
-
Publication number: 20100323925Abstract: A detector system is described including arrays having a plurality of nanoelectronic sensors comprising a channel including a nanostructured element disposed on a substrate, the nanostructured element functionalized by one or more materials disposed on or adjacent to the nanostructured element so as to operatively influence one or more sensor electrical properties. In certain embodiments, the nanostructured element comprise one or more nanotubes, and the functionalization material may include nanoparticles composed of one or more metals, metal oxides, salts, or other inorganic or organic materials or composites of these. In one exemplary embodiment, an array includes plurality of sensors which are configured as field effect transistors, the nanostructured element comprising a randomly dispersed interconnecting network of single-walled carbon nanotubes (SWNTs) having semiconducting properties, and functionalized by deposition of metallic nanoparticles comprising one or more metallic elements.Type: ApplicationFiled: October 2, 2006Publication date: December 23, 2010Inventors: Jean-Christophe P. Gabriel, Vikram Joshi, Sergei Skarupo, Alexander Star, David Thomas
-
Publication number: 20100085067Abstract: Embodiments of nanoelectronic sensors are described, including sensors for detecting analytes such as anesthesia gases, CO2 and the like in human breath. An integrated monitor system and disposable sensor unit is described which permits a number of different anesthetic agents to be identified and monitored, as well as concurrent monitoring of other breath species, such as CO2. The sensor unit may be configured to be compact, light weight, and inexpensive. Wireless embodiments provide such enhancements as remote monitoring. A simulator system for modeling the contents and conditions of human inhalation and exhalation with a selected mixture of a treatment agent is also described, particularly suited to the testing of sensors to be used in airway sampling.Type: ApplicationFiled: September 15, 2009Publication date: April 8, 2010Applicant: Nanomix, Inc.Inventors: Jean-Christophe P. Gabriel, Vikram Joshi, John Loren Passmore, Sergei Skarupo, Alexander Star, Christian Valcke
-
Patent number: 7522040Abstract: A portable sensor device incorporates a low-power, nanostructure sensor coupled to a wireless transmitter. The sensor uses a nanostructure conducting channel, such as a nanotube network, that is functionalized to respond to a selected analyte. A measurement circuit connected to the sensor determines a change in the electrical characteristic of the sensor, from which information concerning the present or absence of the analyte may be determined. The portable sensor device may include a portable power source, such as a battery. It may further include a transmitter for wirelessly transmitting data to a base station.Type: GrantFiled: April 20, 2005Date of Patent: April 21, 2009Assignee: Nanomix, Inc.Inventors: John Loren Passmore, Jean-Christophe P. Gabriel, Alexander Star, Vikram Joshi, Sergei Skarupo