Abstract: The invention relates to chemical and pharmaceutical industry, in particular to technologies of obtaining sterile drugs, drug substances and cosmetic products used in the form of solutions or emulsions, and comprising poloxamer. The thermal method for sterilizing aqueous poloxamer solutions is provided, the method including: dissolving a poloxamer in water for injection; performing the sterilizing filtration of the aqueous poloxamer solution simultaneously with filling sterile containers with the filtered poloxamer solution; sealing the containers containing the poloxamer solution; applying a thermal sterilization with steam under pressure to the containers containing the poloxamer solution, and cooling them, wherein the thermal sterilization of the containers containing the poloxamer solution with steam under pressure is performed under the pressure between 82.4 and 107.8 kPa.

Abstract: The invention relates to the field of medicine, particularly to a method for increasing blood haemoglobin level in a cancer patient. A method for increasing blood haemoglobin level in a cancer patient, wherein a pharmaceutical composition comprising a poloxamer as a pharmacologically active substance is administered before and/or during and/or after a course of the chemotherapy or immunotherapy is provided.

Abstract: The invention relates to the field of medicine and veterinary medicine, in particular to a new use of the poloxamer as a pharmacologically active substance A new use of the poloxamer as a pharmacologically active substance to increase the levels of haemoglobin and red blood cells in a patients blood is revealed. Thus, new pharmacologically active substances that promote a rise in haemoglobin and red blood cell levels in a patients blood were found, the use of which ensures the achievement of the technical result consisting in a significant reduction of the toxic effect and side effects of these substances on the patients body in the case of oral and parenteral administration.

Abstract: The invention relates to chemical and pharmaceutical industry, in particular to technologies of obtaining sterile drugs, drug substances and cosmetic products used in the form of solutions or emulsions, and comprising poloxamer. The thermal method for sterilizing aqueous poloxamer solutions is provided, the method including: dissolving a poloxamer in water for injection; performing the sterilizing filtration of the aqueous poloxamer solution simultaneously with filling sterile containers with the filtered poloxamer solution; sealing the containers containing the poloxamer solution; applying a thermal sterilization with steam under pressure to the containers containing the poloxamer solution, and cooling them, wherein the thermal sterilization of the containers containing the poloxamer solution with steam under pressure is performed under the pressure between 82.4 and 107.8 kPa.