Patents by Inventor Sergey Dzekunov

Sergey Dzekunov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS TO IMPROVE POTENCY OF ELECTROPORATION
    Publication number: 20210395721
    Abstract: Compositions and methods for reducing nucleotide oxidation during electroporation, specifically the use of free radical scavengers to reduce electroporation-induced oxidation, are described. Compositions and methods for enhancing transfection efficiency are also described.
    Type: Application
    Filed: October 23, 2019
    Publication date: December 23, 2021
    Applicants: Codiak BioSciences, Inc., MaxCyte, Inc.
    Inventors: Raymond W. BOURDEAU, Delai CHEN, Rane HARRISON, Kathryn E. GOLDEN, Douglas E. WILLIAMS, Sergey DZEKUNOV, Madhusudan PESHWA
  • METHODS FOR OPTIMIZING ELECTROPORATION
    Publication number: 20170204432
    Abstract: Embodiments of the invention are directed to a technique for electroporation that allows for a delivery of long electrical pulses of high magnitude in highly conductive buffers and minimizes damage to cells undergoing electroporation.
    Type: Application
    Filed: January 27, 2017
    Publication date: July 20, 2017
    Inventor: Sergey DZEKUNOV
  • Methods and devices related to a regulated flow electroporation chamber
    Patent number: 9546350
    Abstract: The electroporation chamber and its related devices combine the features of an electroporation chamber that acts as a manifold for regulation of sample flow with those of a flow electroporation device to form a regulated flow electroporation device. The invention further comprises a novel regulated flow electroporation chamber that enables conditions in which a sample is uniformly processed in individual fractions or volumes in a fully closed (sterile) system.
    Type: Grant
    Filed: August 10, 2010
    Date of Patent: January 17, 2017
    Assignee: Maxcyte, Inc.
    Inventors: Sergey Dzekunov, Nicholas Chopas, Linhong Li
  • METHODS FOR OPTIMIZING ELECTROPORATION
    Publication number: 20120088842
    Abstract: Embodiments of the invention are directed to a technique for electroporation that allows for a delivery of long electrical pulses of high magnitude in highly conductive buffers and minimizes damage to cells undergoing electroporation.
    Type: Application
    Filed: July 15, 2009
    Publication date: April 12, 2012
    Applicant: MAXCYTE, INC.
    Inventor: Sergey Dzekunov
  • METHODS AND DEVICES RELATED TO A REGULATED FLOW ELECTROPORATION CHAMBER
    Publication number: 20110065171
    Abstract: The electroporation chamber and its related devices combine the features of an electroporation chamber that acts as a manifold for regulation of sample flow with those of a flow electroporation device to form a regulated flow electroporation device. The invention further comprises a novel regulated flow electroporation chamber that enables conditions in which a sample is uniformly processed in individual fractions or volumes in a fully closed (sterile) system.
    Type: Application
    Filed: August 10, 2010
    Publication date: March 17, 2011
    Inventors: Sergey Dzekunov, Nicholas Chopas, Linhong Li
  • Methods and devices related to a regulated flow electroporation chamber
    Patent number: 7771984
    Abstract: The electroporation chamber and its related devices combine the features of an electroporation chamber that acts as a manifold for regulation of sample flow with those of a flow electroporation device to form a regulated flow electroporation device. The invention further comprises a novel regulated flow electroporation chamber that enables conditions in which a sample is uniformly processed in individual fractions or volumes in a fully closed (sterile) system.
    Type: Grant
    Filed: May 12, 2005
    Date of Patent: August 10, 2010
    Assignee: Maxcyte, Inc.
    Inventors: Sergey Dzekunov, Nicholas Chopas, Linhong Li
  • Computerized electroporation
    Publication number: 20060172422
    Abstract: Techniques for computerized electroporation. An electroporation apparatus may be controlled according to one of a plurality of previously-saved, user-defined processing protocols. A processing log associated with a processing protocol may be generated, and the processing log may include patient or sample specific information. The processing log or a summary of the processing log may be exported to a user. Interactive instructions may be provided to a user. Those instructions may correspond to one or more steps of a processing protocol.
    Type: Application
    Filed: November 30, 2005
    Publication date: August 3, 2006
    Inventors: Sergey Dzekunov, Sarah Wang, Arthur Hanson
  • Methods and devices related to a regulated flow electroporation chamber
    Publication number: 20050282200
    Abstract: The electroporation chamber and its related devices combine the features of an electroporation chamber that acts as a manifold for regulation of sample flow with those of a flow electroporation device to form a regulated flow electroporation device. The invention further comprises a novel regulated flow electroporation chamber that enables conditions in which a sample is uniformly processed in individual fractions or volumes in a fully closed (sterile) system.
    Type: Application
    Filed: May 12, 2005
    Publication date: December 22, 2005
    Inventors: Sergey Dzekunov, Nicholas Chopas
  • Apparatus and method for streaming electroporation
    Publication number: 20040115784
    Abstract: Techniques for streaming electroporation. A representative but non-limiting method includes: generating a spatially inhomogeneous electric field with a pair of electrodes and displacing the pair of electrodes and a sample relative to one other while the electric field is substantially constant in terms of magnitude so that the sample is displaced across electric field lines for a time sufficient to effect electroporation.
    Type: Application
    Filed: September 30, 2003
    Publication date: June 17, 2004
    Applicant: Maxcyte, Inc.
    Inventor: Sergey Dzekunov