Patents by Inventor Sergey Gershtein
Sergey Gershtein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12208393Abstract: The invention relates to a thermal control system for controlling the temperature of a fluid. In particular, the invention relates to a control system having at least two heating elements, at least one of which is used for directly or indirectly heating a fluid, and at least one of which is used for heating a thermal probe used to determine the temperature of the fluid. The heating systems are controlled by at least one feedback controller.Type: GrantFiled: February 3, 2021Date of Patent: January 28, 2025Assignee: Abbott Point of Care Inc.Inventors: Gary J. Vandersleen, Sergey Gershtein, Mitchell Tilson, Jaymin Patel, Craig H. Schneider, Seth Hunter, Paul Wasserman, Pierre Emeric
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Patent number: 12038403Abstract: This present invention relates generally to devices, systems, and methods for performing optical and electrochemical assays and, more particularly, to devices and systems having universal channel circuitry configured to perform optical and electrochemical assays, and methods of performing the optical and electrochemical assays using the universal channel circuitry. The universal channel circuitry is circuitry that has electronic switching capabilities such that any contact pin, and thus any sensor contact pad in a testing device, can be connected to one or more channels capable of taking on one or more measurement modes or configurations (e.g., an amperometric measurement mode or a current drive mode).Type: GrantFiled: June 9, 2021Date of Patent: July 16, 2024Assignee: Abbott Point of Care Inc.Inventors: Michael Louie Low, Barry Bass, Sergey Gershtein
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Publication number: 20220274109Abstract: This present invention relates generally to devices, systems, and methods for performing bioimaging at the microscopic scale and, more particularly, to devices and systems including a disposable testing device configured to perform bioimaging at the microscopic scale, and methods of performing the bioimaging using the disposable testing device. In some aspects, a testing device is provided for imaging blood cells in a blood sample. The testing device having a sample entry port for receiving the blood sample; a sample testing conduit fluidically connected to the sample entry port, the sample testing conduit including: (i) a planar member, (ii) a transparent planar member, and (iii) a plurality of spacer elements having an average spacer height and disposed between the planar member and the transparent planar member; and an imager chip forming at least a portion of the planar member.Type: ApplicationFiled: May 16, 2022Publication date: September 1, 2022Applicant: Abbott Point of Care Inc.Inventor: Sergey Gershtein
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Patent number: 11369963Abstract: Integrated devices that include a sample preparation component integrated with a detection component are disclosed. The sample preparation component may be a digital microfluidics module or a surface acoustic wave module which modules are used for combing a sample droplet with a reagent droplet and for performing additional sample preparation step leading to a droplet that contains beads/particles/labels that indicate presence or absence of an analyte of interest in the sample. The beads/particles/labels may be detected by moving the droplet to the detection component of the device, which detection component includes an array of wells. Additional analyte detection devices configured to operate an analyte detection chip to prepare a test sample and to detect an analyte related signal from the prepared test sample in the analyte detection chip are disclosed.Type: GrantFiled: April 16, 2020Date of Patent: June 28, 2022Assignee: ABBOTT LABORATORIESInventors: Jeffrey B. Huff, Mark A. Hayden, Graham Davis, Sergey Gershtein
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Publication number: 20220126296Abstract: Integrated devices that include a sample preparation component integrated with a detection component are disclosed. The sample preparation component may be a digital microfluidics module or a surface acoustic wave module which modules are used for combing a sample droplet with a reagent droplet and for performing additional sample preparation step leading to a droplet that contains beads/particles/labels that indicate presence or absence of an analyte of interest in the sample. The beads/particles/labels may be detected by moving the droplet to the detection component of the device, which detection component includes an array of wells. Additional analyte detection devices configured to operate an analyte detection chip to prepare a test sample and to detect an analyte related signal from the prepared test sample in the analyte detection chip are disclosed.Type: ApplicationFiled: November 4, 2021Publication date: April 28, 2022Inventors: Jeffrey B. Huff, Mark A. Hayden, Graham Davis, Sergey Gershtein
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Publication number: 20220113246Abstract: This present invention relates generally to devices, systems, and methods for performing optical and electrochemical assays and, more particularly, to devices and systems having universal channel circuitry configured to perform optical and electrochemical assays, and methods of performing the optical and electrochemical assays using the universal channel circuitry. The universal channel circuitry is circuitry that has electronic switching capabilities such that any contact pin, and thus any sensor contact pad in a testing device, can be connected to one or more channels capable of taking on one or more measurement modes or configurations (e.g., an amperometric measurement mode or a current drive mode).Type: ApplicationFiled: December 23, 2021Publication date: April 14, 2022Applicant: Abbott Point of Care Inc.Inventors: Michael Louie LOW, Barry Bass, Sergey Gershtein
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Patent number: 11253852Abstract: This present invention relates generally to devices, systems, and methods for performing optical and electrochemical assays and, more particularly, to devices and systems having universal channel circuitry configured to perform optical and electrochemical assays, and methods of performing the optical and electrochemical assays using the universal channel circuitry. The universal channel circuitry is circuitry that has electronic switching capabilities such that any contact pin, and thus any sensor contact pad in a testing device, can be connected to one or more channels capable of taking on one or more measurement modes or configurations (e.g., an amperometric measurement mode or a current drive mode).Type: GrantFiled: August 17, 2018Date of Patent: February 22, 2022Assignee: Abbott Point of Care Inc.Inventors: Michael Louie Low, Barry Bass, Sergey Gershtein
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Patent number: 11198129Abstract: Integrated devices that include a sample preparation component integrated with a detection component are disclosed. The sample preparation component may be a digital microfluidics module or a surface acoustic wave module which modules are used for combing a sample droplet with a reagent droplet and for performing additional sample preparation step leading to a droplet that contains beads/particles/labels that indicate presence or absence of an analyte of interest in the sample. The beads/particles/labels may be detected by moving the droplet to the detection component of the device, which detection component includes an array of wells. Additonal analyte detection devices configured to operate an analyte detection chip to prepare a test sample and to detect an analyte related signal from the prepared test sample in the analyte detection chip are disclosed. The analyte detection chip may include a digital microfluidics (DMF) region and an analyte detection region which may overlap or may be spatially separated.Type: GrantFiled: October 5, 2017Date of Patent: December 14, 2021Assignee: Abbott LaboratoriesInventors: Jeffrey B. Huff, Mark A. Hayden, Graham Davis, Sergey Gershtein
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Publication number: 20210325334Abstract: Methods, devices, and systems for analyte analysis using a nanopore are disclosed. The methods, devices, and systems utilize a first and a second binding member that each specifically bind to an analyte in a biological sample. The method further includes detecting and/or counting a cleavable tag attached to the second binding member and correlating the presence and/or the number of tags to presence and/or concentration of the analyte. Certain aspects of the methods do not involve a tag, rather the second binding member may be directly detected/quantitated. The detecting and/or counting may be performed by translocating the tag/second binding member through a nanopore. Devices and systems that are programmed to carry out the disclosed methods are also provided. Also provided herein are instruments that are programmed to operate a cartridge that includes an array of electrodes for actuating a droplet and further includes an electrochemical species sensing region.Type: ApplicationFiled: April 2, 2021Publication date: October 21, 2021Inventors: Jeffrey B. Huff, Mark A. Hayden, Graham Davis, Sergey Gershtein
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Publication number: 20210310978Abstract: This present invention relates generally to devices, systems, and methods for performing optical and electrochemical assays and, more particularly, to devices and systems having universal channel circuitry configured to perform optical and electrochemical assays, and methods of performing the optical and electrochemical assays using the universal channel circuitry. The universal channel circuitry is circuitry that has electronic switching capabilities such that any contact pin, and thus any sensor contact pad in a testing device, can be connected to one or more channels capable of taking on one or more measurement modes or configurations (e.g., an amperometric measurement mode or a current drive mode).Type: ApplicationFiled: June 17, 2021Publication date: October 7, 2021Applicant: Abbott Point of Care Inc.Inventors: Michael Louie LOW, Barry Bass, Sergey Gershtein
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Publication number: 20210293740Abstract: This present invention relates generally to devices, systems, and methods for performing optical and electrochemical assays and, more particularly, to devices and systems having universal channel circuitry configured to perform optical and electrochemical assays, and methods of performing the optical and electrochemical assays using the universal channel circuitry. The universal channel circuitry is circuitry that has electronic switching capabilities such that any contact pin, and thus any sensor contact pad in a testing device, can be connected to one or more channels capable of taking on one or more measurement modes or configurations (e.g., an amperometric measurement mode or a current drive mode).Type: ApplicationFiled: June 9, 2021Publication date: September 23, 2021Applicant: Abbott Point of Care Inc.Inventors: Michael Louie LOW, Barry Bass, Sergey Gershtein
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Patent number: 11067526Abstract: This present invention relates generally to devices, systems, and methods for performing optical and electrochemical assays and, more particularly, to devices and systems having universal channel circuitry configured to perform optical and electrochemical assays, and methods of performing the optical and electrochemical assays using the universal channel circuitry. The universal channel circuitry is circuitry that has electronic switching capabilities such that any contact pin, and thus any sensor contact pad in a testing device, can be connected to one or more channels capable of taking on one or more measurement modes or configurations (e.g., an amperometric measurement mode or a current drive mode).Type: GrantFiled: August 17, 2018Date of Patent: July 20, 2021Assignee: Abbott Point of Care Inc.Inventors: Michael Louie Low, Barry Bass, Sergey Gershtein
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Patent number: 11060994Abstract: This present invention relates generally to devices, systems, and methods for performing optical and electrochemical assays and, more particularly, to devices and systems having universal channel circuitry configured to perform optical and electrochemical assays, and methods of performing the optical and electrochemical assays using the universal channel circuitry. The universal channel circuitry is circuitry that has electronic switching capabilities such that any contact pin, and thus any sensor contact pad in a testing device, can be connected to one or more channels capable of taking on one or more measurement modes or configurations (e.g., an amperometric measurement mode or a current drive mode).Type: GrantFiled: August 17, 2018Date of Patent: July 13, 2021Assignee: Abbott Point of Care Inc.Inventors: Michael Louie Low, Barry Bass, Sergey Gershtein
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Publication number: 20210162418Abstract: The invention relates to a thermal control system for controlling the temperature of a fluid. In particular, the invention relates to a control system having at least two heating elements, at least one of which is used for directly or indirectly heating a fluid, and at least one of which is used for heating a thermal probe used to determine the temperature of the fluid. The heating systems are controlled by at least one feedback controller.Type: ApplicationFiled: February 3, 2021Publication date: June 3, 2021Applicant: Abbott Point of Care Inc.Inventors: Gary J. Vandersleen, Sergey Gershtein, Mitchell Tilson, Jaymin Patel, Craig H. Schneider, Seth Hunter, Paul Wasserman, Pierre Emeric
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Patent number: 11016053Abstract: Methods, devices, and systems for analyte analysis using a nanopore are disclosed. The methods, devices, and systems utilize a first and a second binding member that each specifically bind to an analyte in a biological sample. The method further includes detecting and/or counting a cleavable tag attached to the second binding member and correlating the presence and/or the number of tags to presence and/or concentration of the analyte. Certain aspects of the methods do not involve a tag, rather the second binding member may be directly detected/quantitated. The detecting and/or counting may be performed by translocating the tag/second binding member through a nanopore. Devices and systems that are programmed to carry out the disclosed methods are also provided. Also provided herein are instruments that are programmed to operate a cartridge that includes an array of electrodes for actuating a droplet and further includes an electrochemical species sensing region.Type: GrantFiled: October 5, 2017Date of Patent: May 25, 2021Assignee: Abbott LaboratoriesInventors: Jeffrey B. Huff, Mark A. Hayden, Graham Davis, Sergey Gershtein
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Patent number: 10981172Abstract: The invention relates to a thermal control system for controlling the temperature of a fluid. In particular, the invention relates to a control system having at least two heating elements, at least one of which is used for directly or indirectly heating a fluid, and at least one of which is used for heating a thermal probe used to determine the temperature of the fluid. The heating systems are controlled by at least one feedback controller.Type: GrantFiled: March 12, 2014Date of Patent: April 20, 2021Assignee: Abbott Point of Care Inc.Inventors: Gary J. Vandersleen, Sergey Gershtein, Mitchell Tilson, Jaymin Patel, Craig H. Schneider, Seth Hunter, Paul Wasserman, Pierre Emeric
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Publication number: 20200384470Abstract: Integrated devices that include a sample preparation component integrated with a detection component are disclosed. The sample preparation component may be a digital microfluidics module or a surface acoustic wave module which modules are used for combing a sample droplet with a reagent droplet and for performing additional sample preparation step leading to a droplet that contains beads/particles/labels that indicate presence or absence of an analyte of interest in the sample. The beads/particles/labels may be detected by moving the droplet to the detection component of the device, which detection component includes an array of wells. Additional analyte detection devices configured to operate an analyte detection chip to prepare a test sample and to detect an analyte related signal from the prepared test sample in the analyte detection chip are disclosed.Type: ApplicationFiled: April 16, 2020Publication date: December 10, 2020Inventors: Jeffrey B. Huff, Mark A. Hayden, Graham Davis, Sergey Gershtein
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Patent number: 10852299Abstract: This invention relates generally to devices and methods for performing optical and electrochemical assays and, more particularly, to test devices, e.g., cartridges, methods and systems, wherein the test devices have an entry port configured to receive a test sample into a holding chamber; a first conduit having at least one lateral flow test strip; and a displacement device, such as a pneumatic pump, configured to move a portion of said test sample from said holding chamber into said first conduit. The present invention is particularly useful for performing immunoassays and/or electrochemical assays at the point-of-care.Type: GrantFiled: July 27, 2018Date of Patent: December 1, 2020Assignee: Abbott Point of Care Inc.Inventors: Pierre Emeric, Graham Davis, Thomas Ewart, Sergey Gershtein
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Patent number: 10690664Abstract: This invention relates generally to devices and methods for performing optical and electrochemical assays and, more particularly, to test devices, e.g., cartridges, methods and systems, wherein the test devices have an entry port configured to receive a test sample into a holding chamber; a first conduit having at least one lateral flow test strip; and a displacement device, such as a pneumatic pump, configured to move a portion of said test sample from said holding chamber into said first conduit. The present invention is particularly useful for performing immunoassays and/or electrochemical assays at the point-of-care.Type: GrantFiled: May 25, 2016Date of Patent: June 23, 2020Assignee: Abbott Point of Care Inc.Inventors: Pierre Emeric, Graham Davis, Thomas Ewart, Sergey Gershtein
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Publication number: 20190056329Abstract: This present invention relates generally to devices, systems, and methods for performing optical and electrochemical assays and, more particularly, to devices and systems having universal channel circuitry configured to perform optical and electrochemical assays, and methods of performing the optical and electrochemical assays using the universal channel circuitry. The universal channel circuitry is circuitry that has electronic switching capabilities such that any contact pin, and thus any sensor contact pad in a testing device, can be connected to one or more channels capable of taking on one or more measurement modes or configurations (e.g., an amperometric measurement mode or a current drive mode).Type: ApplicationFiled: August 17, 2018Publication date: February 21, 2019Applicant: Abbott Point of Care Inc.Inventors: Michael Louie LOW, Barry Bass, Sergey Gershtein