Patents by Inventor Sergey V. Voronov

Sergey V. Voronov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reduced artifact denaturing capillary electrophoresis of nucleic acids
    Patent number: 9442091
    Abstract: Described are methods of reducing the incidence and/or magnitude of artifacts in denaturing nucleic acid capillary electrophoresis (CE). Methods and systems described serve to dismiss non-denatured DNA from the tip of the capillary after sample injection and prior to electrophoretic separation of loaded nucleic acids. Among the methods disclosed are the application of a brief reverse-polarity pulse to the capillary prior to separation but after removal of the capillary from the sample reservoir, and transiently heating the capillary to cause expansion of the separation matrix after removal of the capillary from the sample reservoir.
    Type: Grant
    Filed: January 30, 2012
    Date of Patent: September 13, 2016
    Assignee: QIAGEN MANSFIELD, INC.
    Inventors: Sergey V. Voronov, Jork Nolling
  • Methods of nucleic acid quantification and detection using anomalous migration
    Patent number: 9127309
    Abstract: Described are approaches for the identification, detection, and quantification of nucleic acids in a biological sample. These methods are based, in part, on the elucidation of anomalous migration properties of short nucleic acid molecules when conjugated to a fluorescent label, such as fluorescein labels, such that a smaller nucleic acid reliably migrates slower than a larger nucleic acid under the same conditions of separation.
    Type: Grant
    Filed: January 31, 2012
    Date of Patent: September 8, 2015
    Assignee: Qiagen Mansfield, Inc.
    Inventors: Ming-Chou Lee, Sergey V. Voronov, Laurence R. McCarthy, Lilly I. Kong, Vesselin Tenkov Diankov
  • METHODS OF NUCLEIC ACID QUANTIFICATION AND DETECTION USING ANOMALOUS MIGRATION
    Publication number: 20140178872
    Abstract: Described are approaches for the identification, detection, and quantification of nucleic acids in a biological sample. These methods are based, in part, on the elucidation of anomalous migration properties of short nucleic acid molecules when conjugated to a fluorescent label, such as fluorescein labels, such that a smaller nucleic acid reliably migrates slower than a larger nucleic acid under the same conditions of separation.
    Type: Application
    Filed: January 31, 2012
    Publication date: June 26, 2014
    Applicant: PRIMERADX, INC.
    Inventors: Ming-Chou Lee, Sergey V. Voronov, Laurence R. McCarthy, Lilly I. Kong, Vesselin Tenkov Diankov
  • REDUCED ARTIFACT DENATURING CAPILLARY ELECTROPHORESIS OF NUCLEIC ACIDS
    Publication number: 20140021050
    Abstract: Described are methods of reducing the incidence and/or magnitude of artifacts in denaturing nucleic acid capillary electrophoresis (CE). Methods and systems described serve to dismiss non-denatured DNA from the tip of the capillary after sample injection and prior to electrophoretic separation of loaded nucleic acids. Among the methods disclosed are the application of a brief reverse-polarity pulse to the capillary prior to separation but after removal of the capillary from the sample reservoir, and transiently heating the capillary to cause expansion of the separation matrix after removal of the capillary from the sample reservoir.
    Type: Application
    Filed: January 30, 2012
    Publication date: January 23, 2014
    Applicant: PRIMERADX, INC.
    Inventors: Sergey V. Voronov, Jork Nolling