Patents by Inventor Sergio Arce

Sergio Arce has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Adjuvant activities of mutants of LT-IIa and LT-IIb enterotoxin lacking binding to ganglioside
    Patent number: 7776338
    Abstract: The present invention describes the adjuvant activity of mutants of LT-IIa and LT-IIb enterotoxin which lack ganglioside binding activity. The adjuvant activity of the LT-IIb(T13I) mutant is comparable to that of the wild type LT-IIb. The adjuvant activity of LT-IIa(T34I) mutant is also described which exhibits a late onset adjuvant activity. These mutants are useful for enhancing immune response to antigens.
    Type: Grant
    Filed: November 5, 2008
    Date of Patent: August 17, 2010
    Assignee: The Research Foundation of State University of New York
    Inventors: Terry D. Connell, Michael W. Russell, Hesham Nawar, Sergio Arce
  • ADJUVANT ACTIVITIES OF MUTANTS OF LT-IIa AND LT-IIb ENTEROTOXIN LACKING BINDING TO GANGLIOSIDE
    Publication number: 20090136535
    Abstract: The present invention describes the adjuvant activity of mutants of LT-IIa and LT-IIb enterotoxin which lack ganglioside binding activity. The adjuvant activity of the LT-IIb(T13I) mutant is comparable to that of the wild type LT-IIb. The adjuvant activity of LT-IIa(T34I) mutant is also described which exhibits a late onset adjuvant activity. These mutants are useful for enhancing immune response to antigens.
    Type: Application
    Filed: November 5, 2008
    Publication date: May 28, 2009
    Inventors: Terry D. Connell, Michael W. Russell, Hesham Nawar, Sergio Arce
  • Adjuvant activities of mutants of LT-IIa and LT-IIb enterotoxin lacking binding to ganglioside
    Patent number: 7455843
    Abstract: The present invention describes the adjuvant activity of mutants of LT-IIa and LT-IIb enterotoxin which lack ganglioside binding activity. The adjuvant activity of the LT-IIb(T13I) mutant is comparable to that of the wild type LT-IIb. The adjuvant activity of LT-IIa(T34I) mutant is also described which exhibits a late onset adjuvant activity. These mutants are useful for enhancing immune response to antigens.
    Type: Grant
    Filed: September 27, 2004
    Date of Patent: November 25, 2008
    Assignee: Research Foundation of State University of New York, The
    Inventors: Terry D. Connell, Michael W. Russell, Hesham Nawar, Sergio Arce
  • Adjuvant activities of mutants of LT-Ila and LT-IIb enterotoxin lacking binding to ganglioside
    Publication number: 20050169848
    Abstract: The present invention describes the adjuvant activity of mutants of LT-IIa and LT-IIb enterotoxin which lack ganglioside binding activity. The adjuvant activity of the LT-IIb(T13I) mutant is comparable to that of the wild type LT-IIb. The adjuvant activity of LT-IIa(T34I) mutant is also described which exhibits a late onset adjuvant activity. These mutants are useful for enhancing immune response to antigens.
    Type: Application
    Filed: September 27, 2004
    Publication date: August 4, 2005
    Inventors: Terry Connell, Michael Russell, Hesham Nawar, Sergio Arce