Patents by Inventor Sergio Castillo Fernandez

Sergio Castillo Fernandez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11814673
    Abstract: The invention relates to a method for the reclassification of a subject to a more appropriate risk assessment to that obtained using the algorithms for such risk estimation such us but not limited to Framingham, Regicor, Score, Procamor Qrisk based on the presence of different polymorphisms. The invention also relates to a method for determining the risk of suffering a cardiovascular disease by combining the absence or presence of one or more polymorphic markers in a sample from the subject with conventional risk factors for CVD as well as computer-implemented means for carrying out said method.
    Type: Grant
    Filed: August 1, 2012
    Date of Patent: November 14, 2023
    Assignee: GENinCode PLC
    Inventors: Eduardo Salas Pérez-Rasilla, Jaume Marrugat De La Iglesia, Roberto Elosua Llanos, Sergio Castillo Fernandez, Joan Salgado Gomez, José Maria Ordovás Munoz
  • Patent number: 10557170
    Abstract: The invention relates to a method for a more appropriate thromboembolic event risk assessment based on the presence of different genetic variant. The invention also relates to a method for determining the risk of suffering a thromboembolism disease by combining the absence or presence of one or more polymorphic markers in a sample from the subject with conventional risk factors for thromboembolism as well as computer-implemented means for carrying out said method.
    Type: Grant
    Filed: July 17, 2017
    Date of Patent: February 11, 2020
    Assignee: Gendiag.exe, S.L.
    Inventors: Eduardo Salas, José Manuel Soria, Miroslava Ogorelkova, Roberto Elosua Llanos, Joan Vila, Sergio Castillo Fernandez
  • Patent number: 9957565
    Abstract: The invention relates to a method for determining the risk of suffering a cardiovascular disease based on the presence of different polymorphisms as well as to kits for practicing the above method. The invention also relates to a method for determining the risk of suffering a cardiovascular disease by combining the absence or presence of one or more polymorphic markers in a sample from the subject with conventional risk factors for CVD as well as computer-implemented means for carrying out said method.
    Type: Grant
    Filed: June 9, 2010
    Date of Patent: May 1, 2018
    Assignee: Gendiag.exe, S.L.
    Inventors: Eduardo Salas Pérez-Rasilla, Jaume Marrugat De La Iglesia, Roberto Elosua Llanos, Sergio Castillo Fernandez, Joan Salgado Gómez, Jose Maria Ordovás Munoz
  • Publication number: 20180066313
    Abstract: The invention relates to a method for a more appropriate thromboembolic event risk assessment based on the presence of different genetic variant. The invention also relates to a method for determining the risk of suffering a thromboembolism disease by combining the absence or presence of one or more polymorphic markers in a sample from the subject with conventional risk factors for thromboembolism as well as computer-implemented means for carrying out said method.
    Type: Application
    Filed: July 17, 2017
    Publication date: March 8, 2018
    Applicant: Gendiag.exe, S.L.
    Inventors: Eduardo Salas, José Manuel Soria, Miroslava Ogorelkova, Roberto Elosua Llanos, Joan Vila, Sergio Castillo Fernandez
  • Publication number: 20160102355
    Abstract: The invention relates to a method for a more appropriate thromboembolic event risk assessment based on the presence of different genetic variant. The invention also relates to a method for determining the risk of suffering a thromboembolism disease by combining the absence or presence of one or more polymorphic markers in a sample from the subject with conventional risk factors for thromboembolism as well as computer-implemented means for carrying out said method.
    Type: Application
    Filed: October 19, 2015
    Publication date: April 14, 2016
    Applicant: Gendiag.exe, S.L.
    Inventors: Eduardo Salas, José Manuel Soria, Miroslava Ogorelkova, Roberto Elosua Llanos, Joan Vila, Sergio Castillo Fernandez
  • Publication number: 20140342355
    Abstract: The invention relates to a method for the reclassification of a subject to a more appropriate risk assessment to that obtained using the algorithms for such risk estimation such us but not limited to Framingham, Regicor, Score, Procamor Qrisk based on the presence of different polymorphisms. The invention also relates to a method for determining the risk of suffering a cardiovascular disease by combining the absence or presence of one or more polymorphic markers in a sample from the subject with conventional risk factors for CVD as well as computer-implemented means for carrying out said method.
    Type: Application
    Filed: August 1, 2012
    Publication date: November 20, 2014
    Applicant: Gendiag.exe, S.L.
    Inventors: Eduardo Salas Pérez-Rasilla, Jaume Marrrugat De La Iglesia, Roberto Elosua Llanos, Sergio Castillo Fernández, Joan Salgado Gómez, José Maria Ordovás Munoz
  • Patent number: 8669049
    Abstract: The invention relates to extracorporeal methods of analyzing the presence or absence of mutations which cause familial hypercholesterolemia. The inventive methods describe the way in which said mutations can be detected using a DNA sample from an individual and comprising the following: chain reaction of the polymerase with primers which are complementary to the low-density lipoprotein receptor gene; analysis of the amplified product by sequencing; restriction analysis; single strand conformation polymorphism techniques; heteroduplex analysis and analysis of a device on top of a biochip glass support on which oligonucleotide probes are disposed, which can be used to detect the aforementioned mutations in the DNA.
    Type: Grant
    Filed: January 21, 2004
    Date of Patent: March 11, 2014
    Assignee: Progenika Biopharma, S.A.
    Inventors: Pedro Mata Lopez, Rodrigo Alberto Alonso Karlezi, Pilar Mozas Alonso, Gilberto Reyes Leal, Miguel Pocovi Mieras, Sergio Castillo Fernandez, Diego Tejedor Hernandez, Antonio Martinez Martinez, Miguel Mallen Perez
  • Publication number: 20120141450
    Abstract: The invention relates to a method for determining the risk of suffering a cardiovascular disease based on the presence of different polymorphisms as well as to kits for practicing the above method. The invention also relates to a method for determining the risk of suffering a cardiovascular disease by combining the absence or presence of one or more polymorphic markers in a sample from the subject with conventional risk factors for CVD as well as computer-implemented means for carrying out said method.
    Type: Application
    Filed: June 9, 2010
    Publication date: June 7, 2012
    Applicant: GENDIAG.EXE, S.L.
    Inventors: Eduardo Salas Pérez-Rasilla, Jaume Marrugat De La Iglesia, Roberto Elosua Llanos, Sergio Castillo Fernandez, Joan Salgado Gómez, Jose Maria Ordovás Munoz