Patents by Inventor Sergio Contrini

Sergio Contrini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of pure gabapentin “Form II”
    Patent number: 7151193
    Abstract: Pure gabapentin form II can be directly obtained adding the solution of the corresponding hydrochloride in dry ethanol (from which the inorganic salts have been filtered off) with a tertiary amine and a small amount of water.
    Type: Grant
    Filed: February 3, 2004
    Date of Patent: December 19, 2006
    Assignee: Farchemia s.r.l.
    Inventors: Gabriele Breviglieri, Sergio Contrini, Cinzia Assanelli
  • Process for the preparation of gabapentin free from inorganic acids anions
    Patent number: 6790986
    Abstract: Gabapentin free from mineral acids anions is obtained by precipitating from a gabapentin aqueous solution a corresponding hydroxybenzoate, from which pure gabapentin is subsequently obtained by dissolution in a lower alcohol and treatment with a tertiary base.
    Type: Grant
    Filed: May 27, 2003
    Date of Patent: September 14, 2004
    Assignee: Farchemia S.r.l.
    Inventors: Gabriele Breviglieri, Sergio Contrini, Cinzia Assanelli
  • Process for the preparation of pure gabapentin "Form II"
    Publication number: 20040176639
    Abstract: Pure gabapentin form II can be directly obtained adding the solution of the corresponding hydrochloride in dry ethanol (from which the inorganic salts have been filtered off) with a tertiary amine and a small amount of water.
    Type: Application
    Filed: February 3, 2004
    Publication date: September 9, 2004
    Inventors: Gabriele Breviglieri, Sergio Contrini, Cinzia Assanelli
  • Process for the preparation of metaxalone
    Patent number: 6538142
    Abstract: A process for the preparation of 5-(3,5-dimethylphenoxymethyl)-2-oxazolidinone, which includes: a) reacting 3,5-dimethylphonel with epichlorohydrin to obtain a mixture of 1-(3,5-dimethylphenoxy)2,3-epoxy propane (1) and 1-(3,5-dimethylphenoxy)-3-chloro-2-propanol (2); b) reacting the mixture of (1) and (2) obtained from step (a) with benzylamine to obtain a first compound; c) reducing the first compound with hydrogen in presence of ammonia, to obtain a second compound; and d) reacting the second compound with dimethylcarbonate in the presence of a strong base to obtain 5-(3,5-dimethlphenoxymethyl)-2-oxazolidinone.
    Type: Grant
    Filed: April 18, 2002
    Date of Patent: March 25, 2003
    Assignee: Farchemia S.r.l.
    Inventors: Gabriele Breviglieri, Sergio Contrini, Giacomo Bruno, Cinzia Assanelli
  • Process for the preparation of 4.5-diphenyloxazole-2-propanoic acid
    Patent number: 6096896
    Abstract: In a process for the preparation of 4,5-diphenyloxazole-2-propanoic acid, the improvement consisting in using toluene in the esterification reaction of benzoin, and acetic acid/formic acid in the subsequent cyclization, thereby obtaining higher yields and avoiding the use and the disposal of high amounts of pyridine.
    Type: Grant
    Filed: October 15, 1998
    Date of Patent: August 1, 2000
    Assignee: Farchemia s.r.l.
    Inventors: Gabriele Breviglieri, Giacomo Bruno, Sergio Contrini, Cinzia Assanelli
  • Process for the resolution of 6-methoxy-alpha-methyl-2-naphthaleneacetic racemic acid into its enantiomers
    Patent number: 5760287
    Abstract: Naproxene ((+)-6-methoxy-.alpha.-methyl-2-naphthaleneacetic acid) is recovered from the corresponding racemic acid by treatment of the latter with N-substituted R-(-)-2-amino-1-butanols and recovery of the resulting diastereomeric salt.
    Type: Grant
    Filed: April 16, 1996
    Date of Patent: June 2, 1998
    Assignee: Farchemia S.R.L.
    Inventors: Pierre Loosen, Gabriele Breviglieri, Bruno Giagomo, Sergio Contrini, Cineia Assanelli