Abstract: An iontophoresis method of delivering Vitamin C through the skin. The iontophoresis method includes applying to the skin of a biological subject a composition comprising one or more of Vitamin C, Vitamin C derivatives, ions of Vitamin C, and ions of Vitamin C derivatives, and at least an anionic or non-ionic polymer, and applying simultaneously, successively or sequentially overtime a selected current profile, either continuous direct current, pulsed current or a combination of both, from any device and/or support comprising at least one electrode to the skin, the continuous direct current, the pulsed current or the combination of both of a character and for a duration sufficient to transdermally deliver Vitamin C to the biological subject, and transporting different rates of Vitamin C across the skin in accordance to the selected current mode.

Abstract: An electrical method of delivering hyaluronic acid through the skin that includes applying a selected electroporation pulsatile current stimulus, from any device and/or support comprising at least one electrode, the electroporation pulsatile current stimulus being of a character and for a duration sufficient to transdermally deliver hyaluronic acid, for example an aqueous composition, to a biological subject, and transporting different rates of hyaluronic acid across the skin in accordance to the selected current mode.