Patents by Inventor Sergio Madrigal-Carballo
Sergio Madrigal-Carballo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240016147Abstract: The present disclosure provides biodegradable, bioactive biopolymer nanocoating platforms, compositions thereof, and methods for making and producing the biopolymer nanocoating platforms. The present disclosure also provides various agricultural applications of the biodegradable, bioactive biopolymer nanocoating platforms.Type: ApplicationFiled: October 8, 2021Publication date: January 18, 2024Inventors: Joseph FRANK, Sepehr ZOMORODI, Sergio Madrigal CARBALLO, Ameer Hamza SHAKEEL, Payam POURTAHERI
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Publication number: 20230413828Abstract: The present disclosure provides compositions and methods for suppressing growth of various plant species with bioactive agents. Also, the present disclosure provides agricultural compositions and methods of using the formulations containing minicells and bioactive agents for targeted delivery and controlled release to enhance control of various plant species in a stable and scalable manner.Type: ApplicationFiled: November 16, 2021Publication date: December 28, 2023Inventors: Joseph FRANK, Ameer Hamza SHAKEEL, Sergio Madrigal CARBALLO, Sepehr ZOMORODI, Payam POURTAHERI
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Patent number: 11306128Abstract: Methods of purifying mucin, purified mucin, and products comprising the purified mucin. The methods include combining a mucin-containing substance with water and one or more purification agents to form a purification mixture, incubating the purification mixture for a time sufficient to form a mucin precipitate in a liquid phase, and separating the mucin precipitate from the liquid phase. The purification agents include one or more of a surfactant, a chelating agent, and a protic solvent. The mucin purified from the methods can be used alone or in combination with a biopolymer such as a tannin and chitosan and can be used to generate materials in the form of a gel, a foam, a film, or a powder.Type: GrantFiled: December 20, 2019Date of Patent: April 19, 2022Assignee: Wisconsin Alumni Research FoundationInventors: Jess Dreher Reed, Sergio Madrigal-Carballo, Michael Allen Polewski, Christian Gerald Krueger, Emilia Alfaro-Viquez
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Publication number: 20210230777Abstract: Composite nanofibers comprising polymers and tannins, methods of making same, and methods of use. The nanofibers include a polymer, such as a synthetic polymer, and a tannin. The tannin can include condensed tannins (proanthocyanidins) and/or hydrolyzable tannins. The nanofibers exhibit a number of structural and functional characteristics, such as enhanced swelling in aqueous liquid, enhanced antibacterial activity, enhanced bacterial adsorption, enhanced fibroblast adhesion, enhanced fibroblast proliferation, and enhanced surface coating of silver nanoparticles, among others. The nanofibers can be made by electrospinning a solvent mixture comprising the synthetic polymer and the tannin in a solvent. The nanofibers can be used in methods of isolating cells, methods of filtration, and methods of detecting cells, among others.Type: ApplicationFiled: June 11, 2020Publication date: July 29, 2021Applicant: Wisconsin Alumni Research FoundationInventors: Jess Dreher Reed, Christian Gerald KRUEGER, Emilia ALFARO-VIQUEZ, Sergio MADRIGAL-CARBALLO, Hilary Urena SABORIO, Sundaram GUNASEKARAN
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Patent number: 10912822Abstract: Devices for guided tissue regeneration (GTR) include a matrix of chitosan and mutable collagenous tissue (MCT) wherein the chitosan is electrostatically bonded to the MCT to form MCT-chitosan composite material. The MCT can be isolated from invertebrate marine organisms, such as sponges, jellyfish, mollusks and echinoderms. The MCT-chitosan composite material can be formulated as a biofilm, a 3D-sponge, a hydrogel, or as an electrospun nanofiber, or the MCT-chitosan composite material can coat a biomaterial surface. The devices can include wound dressings and tissue sponges, including 3D sponges. Applications include tissue engineering and wound healing, as well as burns and other related guided tissue regeneration applications. MCT and MCT-chitosan composite material, contained in a pharmaceutically acceptable topical carrier, also has cosmeceutical applications, for treating scars, as well as skin discoloration and various pigmentation issues, including melasma/chloasma.Type: GrantFiled: September 6, 2018Date of Patent: February 9, 2021Assignee: Marine Essence Biosciences Corporation of USAInventors: Danny Qiu, Sergio Madrigal Carballo
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Publication number: 20200354431Abstract: The present disclosure relates generally to methods for extracting or purifying collagen type I from marine animals, and uses of the purified collagen type I. Disclosed herein are the methods for the purification of highly pure mutable collagenous tissue from echinoderms. The current disclosure also relates to pharmaceutical, cosmetic and nutritional applications of the mutable collagenous tissue purified using the methods disclosed herein, and to compositions, kits and articles of manufacture made from the mutable collagenous tissue purified using the methods disclosed herein.Type: ApplicationFiled: May 7, 2019Publication date: November 12, 2020Inventors: Danny Qiu, Sergio Madrigal Carballo
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Patent number: 10758594Abstract: Devices for guided tissue regeneration (GTR) include a matrix of chitosan and mutable collagenous tissue (MCT) wherein the chitosan is electrostatically bonded to the MCT to form MCT-chitosan composite material. The MCT can be isolated from invertebrate marine organisms, such as sponges, jellyfish, mollusks and echinoderms. The MCT-chitosan composite material can be formulated as a biofilm, a 3D-sponge, a hydrogel, or as an electrospun nanofiber, or the MCT-chitosan composite material can coat a biomaterial surface. The devices can include wound dressings and tissue sponges, including 3D sponges. Applications include tissue engineering and wound healing, as well as burns and other related guided tissue regeneration applications. MCT and MCT-chitosan composite material, contained in a pharmaceutically acceptable topical carrier, also has cosmeceutical applications, for treating scars, as well as skin discoloration and various pigmentation issues, including melasma/chloasma.Type: GrantFiled: September 6, 2018Date of Patent: September 1, 2020Assignee: Marine Essence Biosciences Corporation of USAInventors: Danny Qiu, Sergio Madrigal Carballo
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Publication number: 20200199185Abstract: Methods of purifying mucin, purified mucin, and products comprising the purified mucin. The methods include combining a mucin-containing substance with water and one or more purification agents to form a purification mixture, incubating the purification mixture for a time sufficient to form a mucin precipitate in a liquid phase, and separating the mucin precipitate from the liquid phase. The purification agents include one or more of a surfactant, a chelating agent, and a protic solvent. The mucin purified from the methods can be used alone or in combination with a biopolymer such as a tannin and chitosan and can be used to generate materials in the form of a gel, a foam, a film, or a powder.Type: ApplicationFiled: December 20, 2019Publication date: June 25, 2020Applicant: Wisconsin Alumni Research FoundationInventors: Jess Dreher Reed, Sergio Madrigal-Carballo, Michael Allen Polewski, Christian Gerald Krueger, Emilia Alfaro-Viquez
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Publication number: 20190388586Abstract: Devices for guided tissue regeneration (GTR) include a matrix of chitosan and mutable collagenous tissue (MCT) wherein the chitosan is electrostatically bonded to the MCT to form MCT-chitosan composite material. The MCT can be isolated from invertebrate marine organisms, such as sponges, jellyfish, mollusks and echinoderms. The MCT-chitosan composite material can be formulated as a biofilm, a 3D-sponge, a hydrogel, or as an electrospun nanofiber, or the MCT-chitosan composite material can coat a biomaterial surface. The devices can include wound dressings and tissue sponges, including 3D sponges. Applications include tissue engineering and wound healing, as well as burns and other related guided tissue regeneration applications. MCT and MCT-chitosan composite material, contained in a pharmaceutically acceptable topical carrier, also has cosmeceutical applications, for treating scars, as well as skin discoloration and various pigmentation issues, including melasma/chloasma.Type: ApplicationFiled: September 6, 2018Publication date: December 26, 2019Applicant: Marine Essence Biosciences Corporation of USAInventors: Danny Qiu, Sergio Madrigal Carballo
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Publication number: 20190388517Abstract: Devices for guided tissue regeneration (GTR) include a matrix of chitosan and mutable collagenous tissue (MCT) wherein the chitosan is electrostatically bonded to the MCT to form MCT-chitosan composite material. The MCT can be isolated from invertebrate marine organisms, such as sponges, jellyfish, mollusks and echinoderms. The MCT-chitosan composite material can be formulated as a biofilm, a 3D-sponge, a hydrogel, or as an electrospun nanofiber, or the MCT-chitosan composite material can coat a biomaterial surface. The devices can include wound dressings and tissue sponges, including 3D sponges. Applications include tissue engineering and wound healing, as well as burns and other related guided tissue regeneration applications. MCT and MCT-chitosan composite material, contained in a pharmaceutically acceptable topical carrier, also has cosmeceutical applications, for treating scars, as well as skin discoloration and various pigmentation issues, including melasma/chloasma.Type: ApplicationFiled: September 6, 2018Publication date: December 26, 2019Applicant: Marine Essence Biosciences Corporation of USAInventors: Danny Qiu, Sergio Madrigal Carballo
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Patent number: 10104888Abstract: The invention provides a composition comprising a matrix of chitosan and a tannin wherein the chitosan is electrostatically bonded to the tannin to form a chitosan-tannin composite material. The chitosan can be partially or fully deacetylated, and the tannin can be a monomeric or an oligomeric proanthocyanidin or a hydrolysable tannin. The chitosan-tannin composite material can be a nanoparticle, a hydrogel film, a bio-foam, or a biogel, or the chitosan-tannin composite material can coat a liposome. The composite materials can be used for drug delivery, for antibacterial and/or antifungal applications, for tissue engineering applications, for wound healing applications, or they can be used as adjuvants for vaccination, including oral vaccinations. The invention also provides methods of preparing the composite materials and their various forms.Type: GrantFiled: December 15, 2016Date of Patent: October 23, 2018Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATIONInventors: Jess Dreher Reed, Christian Gerald Krueger, Sergio Madrigal-Carballo
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Publication number: 20170142967Abstract: The invention provides a composition comprising a matrix of chitosan and a tannin wherein the chitosan is electrostatically bonded to the tannin to form a chitosan-tannin composite material. The chitosan can be partially or fully deacetylated, and the tannin can be a monomeric or an oligomeric proanthocyanidin or a hydrolysable tannin. The chitosan-tannin composite material can be a nanoparticle, a hydrogel film, a bio-foam, or a biogel, or the chitosan-tannin composite material can coat a liposome. The composite materials can be used for drug delivery, for antibacterial and/or antifungal applications, for tissue engineering applications, for wound healing applications, or they can be used as adjuvants for vaccination, including oral vaccinations. The invention also provides methods of preparing the composite materials and their various forms.Type: ApplicationFiled: December 15, 2016Publication date: May 25, 2017Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATIONInventors: Jess Dreher Reed, Christian Gerald Krueger, Sergio Madrigal-Carballo
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Patent number: 9545423Abstract: The invention provides a composition comprising a matrix of chitosan and a tannin wherein the chitosan is electrostatically bonded to the tannin to form a chitosan-tannin composite material. The chitosan can be partially or fully deacetylated, and the tannin can be a monomeric or an oligomeric proanthocyanidin or a hydrolysable tannin. The chitosan-tannin composite material can be a nanoparticle, a hydrogel film, a bio-foam, or a biogel, or the chitosan-tannin composite material can coat a liposome. The composite materials can be used for drug delivery, for antibacterial and/or antifungal applications, for tissue engineering applications, for wound healing applications, or they can be used as adjuvants for vaccination, including oral vaccinations. The invention also provides methods of preparing the composite materials and their various forms.Type: GrantFiled: December 23, 2013Date of Patent: January 17, 2017Assignee: Wisconsin Alumni Research FoundationInventors: Jess Dreher Reed, Christian Gerald Krueger, Sergio Madrigal-Carballo
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Publication number: 20140134238Abstract: The invention provides a composition comprising a matrix of chitosan and a tannin wherein the chitosan is electrostatically bonded to the tannin to form a chitosan-tannin composite material. The chitosan can be partially or fully deacetylated, and the tannin can be a monomeric or an oligomeric proanthocyanidin or a hydrolysable tannin. The chitosan-tannin composite material can be a nanoparticle, a hydrogel film, a bio-foam, or a biogel, or the chitosan-tannin composite material can coat a liposome. The composite materials can be used for drug delivery, for antibacterial and/or antifungal applications, for tissue engineering applications, for wound healing applications, or they can be used as adjuvants for vaccination, including oral vaccinations. The invention also provides methods of preparing the composite materials and their various forms.Type: ApplicationFiled: December 23, 2013Publication date: May 15, 2014Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATIONInventors: Jess Dreher Reed, Christian Gerald Krueger, Sergio Madrigal-Carballo
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Patent number: 8642088Abstract: The invention provides a composition comprising a matrix of chitosan and a tannin wherein the chitosan is electrostatically bonded to the tannin to form a chitosan-tannin composite material. The chitosan can be partially or fully deacetylated, and the tannin can be a monomeric or an oligomeric proanthocyanidin or a hydrolysable tannin. The chitosan-tannin composite material can be a nanoparticle, a hydrogel film, a bio-foam, or a biogel, or the chitosan-tannin composite material can coat a liposome. The composite materials can be used for drug delivery, for antibacterial and/or antifungal applications, for tissue engineering applications, for wound healing applications, or they can be used as adjuvants for vaccination, including oral vaccinations. The invention also provides methods of preparing the composite materials and their various forms.Type: GrantFiled: September 3, 2010Date of Patent: February 4, 2014Assignee: Wisconsin Alumni Research FoundationInventors: Jess Dreher Reed, Christian Gerald Krueger, Sergio Madrigal-Carballo
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Publication number: 20110059162Abstract: The invention provides a composition comprising a matrix of chitosan and a tannin wherein the chitosan is electrostatically bonded to the tannin to form a chitosan-tannin composite material. The chitosan can be partially or fully deacetylated, and the tannin can be a monomeric or an oligomeric proanthocyanidin or a hydrolysable tannin. The chitosan-tannin composite material can be a nanoparticle, a hydrogel film, a bio-foam, or a biogel, or the chitosan-tannin composite material can coat a liposome. The composite materials can be used for drug delivery, for antibacterial and/or antifungal applications, for tissue engineering applications, for wound healing applications, or they can be used as adjuvants for vaccination, including oral vaccinations. The invention also provides methods of preparing the composite materials and their various forms.Type: ApplicationFiled: September 3, 2010Publication date: March 10, 2011Inventors: Jess Dreher Reed, Christian Gerald Krueger, Sergio Madrigal-Carballo