Patents by Inventor Sergio Oehninger

Sergio Oehninger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant, biologically active human zona pellucida protein 3 (HZP3) to test male fertility
    Patent number: 7019114
    Abstract: The invention relates to methods for producing recombinant human zona pellucida protein (“rhZP3”) and glycosylated peptide having biological activity of binding to human spermatozoa. A human ovarian cell line is used to produce rhZP3 having a glycosylation pattern required for full biological activity. Methods of determining useful peptides with binding activity for human sperm and their syntheses, as well as using such peptides and proteins in therapeutics and diagnostics are discussed.
    Type: Grant
    Filed: February 19, 1999
    Date of Patent: March 28, 2006
    Assignee: Eastern Virginia Medical School
    Inventors: Ke-Wen Dong, Sergio Oehninger, William E. Gibbons
  • RECOMBINANT, BIOLOGICALLY ACTIVE HUMAN ZONE PELLUCIDA PROTEINS 3 (HZP3) TO TEST MALE FERTILITY
    Publication number: 20020172982
    Abstract: The invention relates to methods for producing recombinant human zona pellucida protein (“rhZP3”) and glycosylated peptide having biological activity of binding to human spermatozoa. A human ovarian cell line is used to produce rhZP3 having a glycosylation pattern required for full biological activity. Methods of determining useful peptides with binding activity for human sperm and their syntheses, as well as using such peptides and proteins in therapeutics and diagnostics are discussed.
    Type: Application
    Filed: February 19, 1999
    Publication date: November 21, 2002
    Inventors: KE-WEN DONG, SERGIO OEHNINGER, WILLIAM E. GIBBONS