Abstract: Use of heterogeneous nucleation allows the localized reduction of metal salt and also cross-link the carbon precursor in the same region. This cross-linked matrix act as the secondary heterogeneous sites for spontaneous Nano particle synthesis and growth during the process of pyrolysis. Selectively creating heterogeneous sites and reducing the metal precursor using highly focused energy beams create various metal-carbon composites with controlled metal positioning. This is such a unique process where a pretreatment process will control the fabrication of complex metal-carbon composite nano and microstructures. This greatly simplifies the fabrication process, facilitating nanostructures like Nano metal bulbs, nanometal pointed nanogaps and metal sandwich structures with such process. With several advantages ranging from electronics, catalysis, optics and several other bio-functionalization technologies, this enables materials with unique and hybrid advantages.

Abstract: Microfluidic chips, systems, and methods of making and using thereof are described. The microfluid chip includes a disc-shaped transparent layer containing a plurality of cell traps, pillars, and filers, and a support layer attached thereto. The microfluid chip has at least one inlet port in center of the transparent layer for receiving a sample of liquid and cells, and optionally a plastic cover. The microfluid chip can be designed to be suitable for the forces used for cell pairing/fusion in stationary and spinning format, or suitable for a particular cell fusion method such chemical and electrical methods. The microfluid chip is particularly suited for fusing dendritic cells and tumor cells for immunotherapy, or for generating hybridoma.

Abstract: Disclosed is a bottom-up synthesis approach for the fabrication of gold nanoparticles composite carbon thin films based on in situ reduction of gold precursor within a photoresist matrix. This provides the possibility to accumulate noble metal nanostructures both on the surface as wells as in the bulk of a tough material like glassy carbon. With several advantages ranging from electronics, catalysis, optics and several other biofuntionalization technologies, this material is like a hybrid. Moreover, fabrication of micro and Nano level structures make it as a CMEMS and BIOMEMS relevant material for wide range of applications.

Abstract: Use of heterogeneous nucleation allows the localized reduction of metal salt and also cross-link the carbon precursor in the same region. This cross-linked matrix act as the secondary heterogeneous sites for spontaneous Nano particle synthesis and growth during the process of pyrolysis. Selectively creating heterogeneous sites and reducing the metal precursor using highly focused energy beams create various metal-carbon composites with controlled metal positioning. This is such a unique process where a pretreatment process will control the fabrication of complex metal-carbon composite nano and microstructures. This greatly simplifies the fabrication process, facilitating nanostructures like Nano metal bulbs, nanometal pointed nanogaps and metal sandwich structures with such process. With several advantages ranging from electronics, catalysis, optics and several other bio-functionalization technologies, this enables materials with unique and hybrid advantages.

Abstract: Disclosed is a bottom-up synthesis approach for the fabrication of gold nanoparticles composite carbon thin films based on in situ reduction of gold precursor within a photoresist matrix. This provides the possibility to accumulate noble metal nanostructures both on the surface as wells as in the bulk of a tough material like glassy carbon. With several advantages ranging from electronics, catalysis, optics and several other biofunctionalization technologies, this material is like a hybrid. Moreover, fabrication of micro and Nano level structures make it as a CMEMS and BIOMEMS relevant material for wide range of applications.