Patents by Inventor Sergio Osti

Sergio Osti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for detecting and reducing impurities of Lapatinib and salts thereof
    Patent number: 9606089
    Abstract: Impurities of lapatinib such as N-{3-chloro-4-[(2-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)furan-2-yl]quinazoline-4-amine compound of formula (I) or a salt thereof: and analytical methods for identifying and quantifying such impurities of Lapatinib and salts thereof are provided. Also provided is Lapatinib containing less than about 0.05 percent of this and related impurities and methods for preparing such pure forms of Lapatinib.
    Type: Grant
    Filed: September 10, 2014
    Date of Patent: March 28, 2017
    Assignee: F.I.S.—FABBRICA ITALIANA SINTETICI S.P.A.
    Inventors: Francesco Fontana, Alessandro Leganza, Sergio Osti
  • METHODS FOR DETECTING AND REDUCING IMPURITIES OF LAPATINIB AND SALTS THEREOF
    Publication number: 20150260696
    Abstract: Impurities of lapatinib such as N-{3-chloro-4-[(2-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)furan-2-yl]quinazoline-4-amine compound of formula (I) or a salt thereof: and analytical methods for identifying and quantifying such impurities of Lapatinib and salts thereof are provided. Also provided is Lapatinib containing less than about 0.05 percent of this and related impurities and methods for preparing such pure forms of Lapatinib.
    Type: Application
    Filed: September 10, 2014
    Publication date: September 17, 2015
    Inventors: Francesco FONTANA, Alessandro Leganza, Sergio Osti
  • Moxifloxacin hydrochloride compounds and intermediates and methods for making same
    Patent number: 8975408
    Abstract: Methods for producing moxifloxacin hydrochloride compounds having very low levels of impurities are provided. Compounds produced using such methods and pharmaceutical compositions including such compounds are also provided.
    Type: Grant
    Filed: January 20, 2014
    Date of Patent: March 10, 2015
    Assignee: F.I.S.—Fabbrica Italiana Sintetici S.p.A.
    Inventors: Gianni Gottardo, Pierluigi Padovan, Sergio Osti
  • Methods for detecting and reducing impurities of Lapatinib and salts thereof
    Patent number: 8927558
    Abstract: Impurities of lapatinib such as N-{3-chloro-4-[(2-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)furan-2-yl]quinazoline-4-amine compound of formula (I) or a salt thereof: and analytical methods for identifying and quantifying such impurities of Lapatinib and salts thereof are provided. Also provided is Lapatinib containing less than about 0.05 percent of this and related impurities and methods for preparing such pure forms of Lapatinib.
    Type: Grant
    Filed: May 14, 2012
    Date of Patent: January 6, 2015
    Assignee: F.I.S.—Fabbrica Italiana Sintetici S.p.A.
    Inventors: Francesco Fontana, Alessandro Leganza, Sergio Osti
  • MOXIFLOXACIN HYDROCHLORIDE COMPOUNDS AND INTERMEDIATES AND METHODS FOR MAKING SAME
    Publication number: 20140135501
    Abstract: Methods for producing moxifloxacin hydrochloride compounds having very low levels of impurities are provided. Compounds produced using such methods and pharmaceutical compositions including such compounds are also provided.
    Type: Application
    Filed: January 20, 2014
    Publication date: May 15, 2014
    Applicant: F.I.S. - FABBRICA ITALIANA SINTETICI S.p.A.
    Inventors: Gianni Gottardo, Pierluigi Padovan, Sergio Osti
  • Moxifloxacin hydrochloride compounds and intermediates and methods for making same
    Patent number: 8664398
    Abstract: Methods for producing moxifloxacin hydrochloride compounds having very low levels of impurities are provided. Compounds produced using such methods and pharmaceutical compositions including such compounds are also provided.
    Type: Grant
    Filed: July 9, 2012
    Date of Patent: March 4, 2014
    Assignee: F.I.S.—Fabbrica Italiana Sintetici S.p.A.
    Inventors: Gianni Gottardo, Pierluigi Padovan, Sergio Osti
  • MOXIFLOXACIN HYDROCHLORIDE COMPOUNDS AND INTERMEDIATES AND METHODS FOR MAKING SAME
    Publication number: 20130059880
    Abstract: Methods for producing moxifloxacin hydrochloride compounds having very low levels of impurities are provided. Compounds produced using such methods and pharmaceutical compositions including such compounds are also provided.
    Type: Application
    Filed: July 9, 2012
    Publication date: March 7, 2013
    Applicant: F.I.S. - FABBRICA ITALIANA SINTETICI S.p.A.
    Inventors: Gianni Gottardo, Pierluigi Padovan, Sergio Osti
  • METHODS FOR DETECTING AND REDUCING IMPURITIES OF LAPATINIB AND SALTS THEREOF
    Publication number: 20120295928
    Abstract: Impurities of lapatinib such as N-{3-chloro-4-[(2-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)furan-2-yl]quinazoline-4-amine compound of formula (I) or a salt thereof: and analytical methods for identifying and quantifying such impurities of Lapatinib and salts thereof are provided. Also provided is Lapatinib containing less than about 0.05 percent of this and related impurities and methods for preparing such pure forms of Lapatinib.
    Type: Application
    Filed: May 14, 2012
    Publication date: November 22, 2012
    Applicant: F.I.S. FABBRICA ITALIANA SINTETICI S.p.A.
    Inventors: Francesco Fontana, Alessandro Leganza, Sergio Osti