Patents by Inventor Sergiusz Markowicz

Sergiusz Markowicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptide preparations and peptides with antitumour activity
    Patent number: 9365633
    Abstract: The subject of the present invention are peptide preparations obtained via the enzymatic digestion of hair, wool, bristles, animal fur and individual peptides with sequences corresponding to individual components of a peptide preparation with antitumor activity, for use in the treatment of tumors or oncological prophylaxis as basal components or components of compositions of substances for treating tumors or components of substances used in oncological prophylaxis.
    Type: Grant
    Filed: December 6, 2011
    Date of Patent: June 14, 2016
    Assignee: Instytut Medycyny Doswiadczalnej I Klinicznej Pan
    Inventors: Andrzej Lipkowski, Sergiusz Markowicz
  • PEPTIDE PREPARATIONS AND PEPTIDES WITH ANTITUMOUR ACTIVITY
    Publication number: 20140315824
    Abstract: The subject of the present invention are peptide preparations obtained via the enzymatic digestion of hair, wool, bristles, animal fur and individual peptides with sequences corresponding to individual components of a peptide preparation with antitumour activity, for use in the treatment of tumours or oncological prophylaxis as basal components or components of compositions of substances for treating tumours or components of substances used in oncological prophylaxis.
    Type: Application
    Filed: December 6, 2011
    Publication date: October 23, 2014
    Applicant: Instytut Medycyny Doswiadczalnej i Klinicznej Pan
    Inventors: Andrzej Lipkowski, Sergiusz Markowicz
  • Methods for using dendritic cells to activate gamma/delta-T cell receptor-positive T cells
    Patent number: 6821778
    Abstract: This invention relates to methods of using human dendritic cells to present antigens for the induction of antigen-specific T cell-mediated immune responses. In particular, it relates to the isolation of dendritic cells from human blood, exposing the cells to antigens, co-culturing the antigen-pulsed dendritic cells with &ggr;&dgr;-T cell receptor-positive-T cells (&ggr;&dgr;-TCR+ T cells) obtained from unprimed or weakly primed individuals for the stimulation of antigen-specific T cell proliferative and cytotoxic activities. The dendritic cell antigen presentation system described herein has a wide range of applications, including but not limited to, activation and expansion of large numbers of antigen-specific major histocompatibility complex-unrestricted T cells for use in adoptive cellular immunotherapy against infectious diseases and cancer.
    Type: Grant
    Filed: February 28, 1996
    Date of Patent: November 23, 2004
    Assignee: The Board of Trustees of Leland Stanford Junior University
    Inventors: Edgar G. Engleman, Anita Mehta, Masaru Takamizawa, Francesco Fagnoni, Sergiusz Markowicz