Patents by Inventor Serguei Kotenko

Serguei Kotenko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Accessory factory function for interferon gamma and its receptor
    Patent number: 6287853
    Abstract: This invention relates (a) to a 540 kb YAC which encodes the necessary species-specific factor(s) and is able to substitute for human Chromosome 21 to reconstitute the Hu-IFN-gamma receptor-mediated induction of class I HLA antigens; (b) to the construction of a plasmid to integrate the selective marker for antibiotic G418 resistance into YACs and to delete some of the human DNA fragments from YACs in order to facilitate the manipulation of human genomic DNA in yeast artificial chromosome (YAC) clones; (c) to two fragmentation vectors, pSE1 and pSE2, which contain a neomycin resistance and URA3 gene, developed for targeting yeast artificial chromosomes (YACs) containing human genomic DNA; (d) to a chromosomal fragmentation procedure employed to produce a deletion set of yeast artificial chromosomes (YACs) from a parental YAC (GART D142H8) known to map to Chromosome 21q and to encode the human interferon-gamma receptor (Hu-IFN-gamma R) accessory factor gene as well as the phosphoribosylglycinamide formyltranis
    Type: Grant
    Filed: June 9, 1997
    Date of Patent: September 11, 2001
    Assignee: University of Medicine & Dentistry of New Jersey
    Inventors: Sidney Pestka, Serguei Kotenko, Jaemog Soh, Robert J. Donnelly, Thomas M. Mariano, Jeffry R. Cook, Stuart Emanuel, Barbara Schwartz