Patents by Inventor Serguei Nabirochkin

Serguei Nabirochkin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS FOR TREATING CMT AND RELATED DISORDERS
    Publication number: 20230233552
    Abstract: The present invention relates to compositions and methods for the treatment of the Charcot-Marie-Tooth disease and related disorders.
    Type: Application
    Filed: January 18, 2023
    Publication date: July 27, 2023
    Inventors: Daniel COHEN, Serguei NABIROCHKIN, Ilya CHUMAKOV
  • Compositions for treating CMT and related disorders
    Patent number: 11672796
    Abstract: The present invention relates to compositions and methods for the treatment of the Charcot-Marie-Tooth disease and related disorders.
    Type: Grant
    Filed: December 23, 2020
    Date of Patent: June 13, 2023
    Assignee: PHARNEXT
    Inventors: Daniel Cohen, Serguei Nabirochkin, Ilya Chumakov
  • Compositions for treating CMT and related disorders
    Patent number: 11576908
    Abstract: The present invention relates to compositions and methods for the treatment of the Charcot-Marie-Tooth disease and related disorders.
    Type: Grant
    Filed: February 10, 2020
    Date of Patent: February 14, 2023
    Assignee: PHARNEXT
    Inventors: Daniel Cohen, Ilya Chumakov, Serguei Nabirochkin
  • Therapeutic approaches for treating Alzheimer disease and related disorders through a modulation of angiogenesis
    Patent number: 11291670
    Abstract: The present invention relates to compositions and methods for the treatment of Alzheimer's disease and related disorders. More particularly, the invention relates to combined therapies that modulate angiogenesis for treating said disease.
    Type: Grant
    Filed: October 29, 2010
    Date of Patent: April 5, 2022
    Assignee: PHARNEXT
    Inventors: Daniel Cohen, Ilya Chumakov, Serguei Nabirochkin, Esther Graudens
  • COMPOSITIONS FOR TREATING CMT AND RELATED DISORDERS
    Publication number: 20210322402
    Abstract: The present invention relates to compositions and methods for the treatment of the Charcot-Marie-Tooth disease and related disorders.
    Type: Application
    Filed: December 23, 2020
    Publication date: October 21, 2021
    Inventors: Daniel COHEN, Serguei NABIROCHKIN, Ilya CHUMAKOV
  • EARLY TREATMENT OF CMT DISEASE
    Publication number: 20210260053
    Abstract: The present invention provides methods for treating, preventing, or delaying the onset of Charcot-Marie-Tooth Disease type 1A (CMT1A), by administering to a subject in need thereof a combination comprising baclofen, sorbitol and naltrexone, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: March 8, 2021
    Publication date: August 26, 2021
    Inventors: Daniel Cohen, Ilya Chumakov, Rodolphe Hajj, Aude Milet, Serguei Nabirochkin, Klaus-Armin Nave, Thomas Prukop, Michael Sereda
  • BACLOFEN AND ACAMPROSATE BASED THERAPY OF ALZHEIMER'S DISEASE IN PATIENTS HAVING LOST RESPONSIVENESS TO ACETYLCHOLINESTERASE INHIBITOR THERAPY
    Publication number: 20210236445
    Abstract: The present invention relates to combinations and methods based on Baclofen and Acamprosate for the treatment of Alzheimer's disease or Alzheimer's related disorders in patients who do not respond to an inhibitor of acetylcholinesterase, typically in patients treated with an inhibitor of acetylcholinesterase and who have lost responsiveness to said inhibitor of acetylcholinesterase.
    Type: Application
    Filed: January 28, 2019
    Publication date: August 5, 2021
    Inventors: ANTHONY BRUREAU, NATHALIE CHOLET, DANIEL COHEN, RODOLPHE HAJJ, SERGUEI NABIROCHKIN
  • THERAPEUTIC APPROACHES FOR TREATING EPILEPSY AND RELATED DISORDERS THROUGH REDUCTION OF EPILEPTOGENESIS
    Publication number: 20210069135
    Abstract: The present invention relates to compositions and methods for the treatment of epilepsy and related disorders. More specifically, the present invention relates to novel combinatorial therapies of epilepsy and related disorders.
    Type: Application
    Filed: November 17, 2020
    Publication date: March 11, 2021
    Inventors: Daniel Cohen, Serguei Nabirochkin, llya Chumakov
  • Early treatment of CMT disease
    Patent number: 10940147
    Abstract: The present invention provides methods for treating, preventing, or delaying the onset of Charcot-Marie-Tooth Disease type 1A (CMT1A), by administering to a subject in need thereof a combination comprising baclofen, sorbitol and naltrexone, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: July 8, 2019
    Date of Patent: March 9, 2021
    Assignee: Pharnext
    Inventors: Daniel Cohen, Ilya Chumakov, Rodolphe Hajj, Aude Milet, Serguei Nabirochkin, Klaus-Armin Nave, Thomas Prukop, Michael Sereda
  • Combination of baclofen, acamprosate and medium chain triglycerides for the treatment of neurological disorders
    Patent number: 10905672
    Abstract: The present invention relates to combinations and methods for the treatment of neurological disorders related to amyloid beta toxicity and/or neuronal death and/or glucose-impaired neuronal metabolism. More specifically, the present invention relates to novel combinatorial therapies of Alzheimer's disease, Alzheimer's disease-related disorders, frontotemporal dementia, Parkinson's disease, Lewy body dementia, Huntington's disease, peripheral neuropathies, alcoholism or alcohol withdrawal, neurological manifestations of drug abuse or drug abuse withdrawal, amyotrophic lateral sclerosis, multiple sclerosis, spinal cord injury, epilepsy, traumatic brain injury or brain ischemic events based on baclofen, acamprosate and at least one medium chain triglyceride.
    Type: Grant
    Filed: February 10, 2015
    Date of Patent: February 2, 2021
    Assignee: PHARNEXT
    Inventors: Daniel Cohen, Ilya Chumakov, Serguei Nabirochkin, Rodolphe Hajj
  • Compositions for treating CMT and related disorders
    Patent number: 10905686
    Abstract: The present invention relates to compositions and methods for the treatment of the Charcot-Marie-Tooth disease and related disorders.
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: February 2, 2021
    Assignee: Pharnext
    Inventors: Daniel Cohen, Serguei Nabirochkin, Ilya Chumakov
  • Therapeutic approaches for treating Alzheimer disease and related disorders through a modulation of synapse function
    Patent number: 10874644
    Abstract: Compositions and methods for the treatment of Alzheimer's disease and related disorders. More particularly, disclosed are combined therapies that modulate synapse function for treating the disease.
    Type: Grant
    Filed: June 6, 2019
    Date of Patent: December 29, 2020
    Assignee: Pharnext
    Inventors: Daniel Cohen, Ilya Chumakov, Serguei Nabirochkin, Oxana Guerassimenko, Nathalie Cholet
  • Stable oral solutions for combined API
    Patent number: 10849851
    Abstract: The present invention relates to a homogeneous, stable, and palatable pharmaceutical solution comprising baclofen, sorbitol and naltrexone.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: December 1, 2020
    Assignee: Pharnext
    Inventors: Daniel Cohen, Ilya Chumakov, Serguei Nabirochkin, Viviane Bertrand
  • Idalopirdine-based combinatorial therapies of Alzheimer's disease
    Patent number: 10736876
    Abstract: The present invention relates to combinatorial therapies and methods for the treatment of Alzheimer's disease or an Alzheimer's disease related disorder based on idalopirdine, baclofen and acamprosate, wherein idalopirdine is provided as suboptimal doses.
    Type: Grant
    Filed: April 23, 2018
    Date of Patent: August 11, 2020
    Assignee: PHARNEXT
    Inventors: Daniel Cohen, Serguei Nabirochkin, Rodolphe Hajj, Anthony Brureau
  • COMPOSITIONS FOR TREATING CMT AND RELATED DISORDERS
    Publication number: 20200237750
    Abstract: The present invention relates to compositions and methods for the treatment of the Charcot-Marie-Tooth disease and related disorders.
    Type: Application
    Filed: February 10, 2020
    Publication date: July 30, 2020
    Inventors: Daniel COHEN, Ilya CHUMAKOV, Serguei NABIROCHKIN
  • COMPOSITIONS, METHODS AND USES FOR THE TREATMENT OF DIABETES AND RELATED CONDITIONS BY CONTROLLING BLOOD GLUCOSE LEVEL
    Publication number: 20200222409
    Abstract: The present invention relates to compositions and methods for controlling glycaemia in a mammalian in need thereof. The present invention relates to compositions and methods for the treatment of diabetes disease and related disorders. More specifically, the present invention relates to novel therapies or combinatorial therapies of diabetes and related disorders, based on compositions controlling the blood glucose level.
    Type: Application
    Filed: March 26, 2020
    Publication date: July 16, 2020
    Inventors: DANIEL COHEN, ILYA CHUMAKOV, SERGUEI NABIROCHKIN, RODOLPHE HAJJ
  • Compositions for treating amyotrophic lateral sclerosis
    Patent number: 10682342
    Abstract: The present invention relates to compositions and methods for the treatment of amyotrophic lateral sclerosis. More specifically, the present invention relates to novel combinatorial therapies for treating amyotrophic lateral sclerosis or a related disorder.
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: June 16, 2020
    Assignee: PHARNEXT
    Inventors: Daniel Cohen, Serguei Nabirochkin, Ilya Chumakov, Rodolphe Hajj
  • THERAPEUTIC APPROACHES FOR TREATING CMT AND RELATED DISORDERS
    Publication number: 20200155491
    Abstract: Compositions and methods for the treatment of Charcot-Marie-Tooth disease and related disorders. Also provided are combination therapies for treating this disease by decreasing PMP22 expression in a subject.
    Type: Application
    Filed: September 27, 2019
    Publication date: May 21, 2020
    Inventors: Daniel COHEN, Ilya CHUMAKOV, Oxana GUERASSIMENKO, Serguei NABIROCHKIN
  • IDALOPIRDINE-BASED COMBINATORIAL THERAPIES OF ALZHEIMER'S DISEASE
    Publication number: 20200129479
    Abstract: The present invention relates to combinatorial therapies and methods for the treatment of Alzheimer's disease or an Alzheimer's disease related disorder based on idalopirdine, baclofen and acamprosate, wherein idalopirdine is provided as suboptimal doses.
    Type: Application
    Filed: April 23, 2018
    Publication date: April 30, 2020
    Inventors: DANIEL COHEN, SERGUEI NABIROCHKIN, RODOLPHE HAJJ, ANTHONY BRUREAU
  • Compositions, methods and uses for the treatment of diabetes and related conditions by controlling blood glucose level
    Patent number: 10617689
    Abstract: The present invention relates to compositions and methods for controlling glycaemia in a mammalian in need thereof. The present invention relates to compositions and methods for the treatment of diabetes disease and related disorders. More specifically, the present invention relates to novel therapies or combinatorial therapies of diabetes and related disorders, based on compositions controlling the blood glucose level.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: April 14, 2020
    Assignee: PHARNEXT
    Inventors: Daniel Cohen, Ilya Chumakov, Serguei Nabirochkin, Rodolphe Hajj