Patents by Inventor Seth A. Fidel

Seth A. Fidel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Retroviral vector particles for transducing non-proliferating cells
    Patent number: 5580766
    Abstract: Retroviral vector particles are provided which contain: 1) oncoretroviral gag, pol, and env proteins, including an oncoretroviral gag capsid protein which has been mutated so as to contain a nuclear localization signal (NLS) sequence; and 2) at least one exogenous gene. The particles can be used to transduce non-proliferating cells, including stem cells and neurons. The presence of the NLS sequence allows the at least one exogenous gene to enter into the nucleus of a target cell, thus allowing integration of the gene into the genome of the target cell.
    Type: Grant
    Filed: January 14, 1994
    Date of Patent: December 3, 1996
    Assignee: Alexion Pharmaceuticals, Inc.
    Inventors: James M. Mason, Scott P. Kennedy, Seth A. Fidel