Abstract: An esophageal ablation system including a positioner, an elongated, flexible shaft extending from the positioner, and a microwave emitter assembly disposed near the distal end of the shaft. The emitter assembly includes one or more microwave antennae and a balloon for spacing the antennae relative to target tissue. The device may have an inner balloon for deploying the antenna. The systems, devices and methods disclosed are useful for treating Barrett's Esophagus, Esophageal Adenocarcinoma, and Squamous Cell Carcinoma.

Abstract: An esophageal ablation system including a positioner, an elongated, flexible shaft extending from the positioner, and a microwave emitter assembly disposed near the distal end of the shaft. The emitter assembly includes one or more microwave antennae and a balloon for spacing the antennae relative to target tissue. The device may have an inner balloon for deploying the antenna. The systems, devices and methods disclosed are useful for treating Barrett's Esophagus, Esophageal Adenocarcinoma, and Squamous Cell Carcinoma.

Abstract: An esophageal ablation system including a positioner, an elongated, flexible shaft extending from the positioner, and a microwave emitter assembly disposed near the distal end of the shaft. The emitter assembly includes one or more microwave antennas and a balloon for spacing the antennas relative to target tissue. The device may have an inner balloon for deploying the antenna. The systems, devices and methods disclosed are useful for treating Barrett's Esophagus, Esophageal Adenocarcinoma, and Squamous Cell Carcinoma.

Abstract: An esophageal ablation system including a positioner, an elongated, flexible shaft extending from the positioner, and a microwave emitter, assembly disposed near the distal end of the shaft. The emitter assembly includes one or more microwave antennas and a balloon for spacing the antennas relative to target tissue. The device may have an inner balloon for deploying the antenna. The systems, devices and methods disclosed are useful for treating Barrett's Esophagus, Esophageal Adenocarcinoma, and Squamous Cell Carcinoma.

Abstract: An esophageal ablation system including a positioner, an elongated, flexible shaft extending from the positioner, and a microwave emitter assembly disposed near the distal end of the shaft. The emitter assembly includes one or more microwave antennae and a balloon for spacing the antennae relative to target tissue. The device may have an inner balloon for deploying the antenna. The systems, devices and methods disclosed are useful for treating Barrett's Esophagus, Esophageal Adenocarcinoma, and Squamous Cell Carcinoma.

Abstract: An esophageal ablation system including a positioner, an elongated, flexible shaft extending from the positioner, and a microwave emitter, assembly disposed near the distal end of the shaft. The emitter assembly includes one or more microwave antennas and a balloon for spacing the antennas relative to target tissue. The device may have an inner balloon for deploying the antenna. The systems, devices and methods disclosed are useful for treating Barrett's Esophagus, Esophageal Adenocarcinoma, and Squamous Cell Carcinoma.

Abstract: A microwave ablation system and method is disclosed comprising a balloon catheter apparatus and a control system. The balloon catheter apparatus comprises a catheter configured to house a coaxial cable and one or more coolant channels, an inflatable balloon located at the distal end of the catheter, and an antenna positioned in the inflatable balloon and in communication with the coaxial cable. The control system comprises a fluid pump configured to introduce fluid into a proximal end of the catheter, a power amplifier capable of generating microwave energy for delivery to the target tissue zone for at least one energy application cycle ranging from 60 seconds to 600 seconds at a frequency ranging from 2.4 GHz to 2.5 GHz, and a computer system configured to monitor and/or regulate the delivery of microwave energy to the target tissue, the fluid pump, at least one sensor, and antenna reflected power.

Abstract: An esophageal ablation system including a positioner, an elongated, flexible shaft extending from the positioner, and a microwave emitter assembly disposed near the distal end of the shaft. The emitter assembly includes one or more microwave antennae and a balloon tor spacing the antennae relative to target tissue. The device may have an inner balloon for deploying the antenna. The systems, devices and methods disclosed are useful for treating Barrett's Esophagus, Esophageal Adenocarcinoma, and Squamous Cell Carcinoma.

Abstract: A microware emitter cable system is disclosed. The system can have a coaxial cable that can have an outer conductor, dielectric insulator radially inside the outer conductor, and an inner conductor radially inside of the dielectric. The system can have multiple passageways radially inside of the outer conductor. The passageways can extend to the distal terminal end of the cable.

Abstract: A microware emitter cable system is disclosed. The system can have a coaxial cable that can have an outer conductor, dielectric insulator radially inside the outer conductor, and an inner conductor radially inside of the dielectric. The system can have multiple passageways radially inside of the outer conductor. The passageways can extend to the distal terminal end of the cable.

Abstract: A microwave ablation system and method is disclosed comprising a balloon catheter apparatus and a control system. The balloon catheter apparatus comprises a catheter configured to house a coaxial cable and one or more coolant channels, an inflatable balloon located at the distal end of the catheter, and an antenna positioned in the inflatable balloon and in communication with the coaxial cable. The control system comprises a fluid pump configured to introduce fluid into a proximal end of the catheter, a power amplifier capable of generating microwave energy for delivery to the target tissue zone for at least one energy application cycle ranging from 60 seconds to 600 seconds at a frequency ranging from 2.4 GHz to 2.5 GHz, and a computer system configured to monitor and/or regulate the delivery of microwave energy to the target tissue, the fluid pump, at least one sensor, and antenna reflected power.

Abstract: A method and balloon catheter apparatus for tissue ablation is disclosed. The apparatus comprises an elongated shaft having a proximal end, a distal end, one or more central lumens, adapted for positioning in an artery; an emitter capable of emitting microwave energy positioned at the distal end; an inflatable balloon associated with the emitter at the distal end configured to allow blood to pass through the artery while the balloon is inflated; and a control system at the proximal end. The method and balloon catheter apparatus is applicable at least to renal denervation procedures.