Abstract: The brace includes one or more air inflatable bladders equipped with an automatic, regulated, and removable air pressure regulation valve, where different valves have different release settings. In addition, a removable, thermally responsive material for hot and cold therapy may be placed in a pocket between the outer and inner material for the brace. The inside surface of the brace is comprised of an absorbent material that absorbs body perspiration, and then releases it to the atmosphere. The brace is placed around the injured area of the patient so that the air bladder(s) lies against the injured area. Air is then introduced into the air bladder via an air inlet valve, forming a compressive force on the body part in contact. In another embodiment of the brace, pneumatic compression is obtained by the use of two or more overlapping air inflatable bladders, each having an air regulation valve with a different pressure release level, wherein the pressure is higher distally and lower ventrally.