Patents by Inventor Seth Kligerman

Seth Kligerman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and apparatus for individually optimizing uniform contrast enhancements in computed tomography imaging
    Patent number: 9456798
    Abstract: A method is provided for optimizing a contrast injection function for CT imaging. The method includes injecting, with an injector pump, a test bolus of a contrast agent into a subject. The method also includes computing, on a processor, an impulse enhancement function. The method also includes determining, on a processor, a target enhancement function for a region of interest. The method also includes determining, with a processor, a plurality of parameters for a functional form for a contrast injection function in a time domain. The method also includes determining for the contrast injection function a constraint. The method also includes determining, with a processor, particular values for the plurality of parameters, which satisfy the constraint and minimize a difference between a value of an enhancement function and the target enhancement function computed in the time domain at discrete time periods without use of a Fourier transform.
    Type: Grant
    Filed: May 12, 2015
    Date of Patent: October 4, 2016
    Assignee: The University of Maryland, Baltimore
    Inventors: Ming Xue, Wei Lu, Seth Kligerman, Hao Zhang, Warren D'Souza, Wookjin Choi
  • METHODS AND APPARATUS FOR INDIVIDUALLY OPTIMIZING UNIFORM CONTRAST ENHANCEMENTS IN COMPUTED TOMOGRAPHY IMAGING
    Publication number: 20150324979
    Abstract: A method is provided for optimizing a contrast injection function for CT imaging. The method includes injecting, with an injector pump, a test bolus of a contrast agent into a subject. The method also includes computing, on a processor, an impulse enhancement function. The method also includes determining, on a processor, a target enhancement function for a region of interest. The method also includes determining, with a processor, a plurality of parameters for a functional form for a contrast injection function in a time domain. The method also includes determining for the contrast injection function a constraint. The method also includes determining, with a processor, particular values for the plurality of parameters, which satisfy the constraint and minimize a difference between a value of an enhancement function and the target enhancement function computed in the time domain at discrete time periods without use of a Fourier transform.
    Type: Application
    Filed: May 12, 2015
    Publication date: November 12, 2015
    Applicant: The University of Maryland, Baltimore
    Inventors: Ming Xue, Wei Lu, Seth Kligerman, Hao Zhang, Warren D'Souza, Wookjin Choi